Annotation Detail for RGS10
Basic Information Top
| Gene Symbol: | RGS10 ( - ) |
|---|---|
| Gene Full Name: | regulator of G-protein signaling 10 |
| Band: | 10q26.11 |
| Quick Links | Entrez ID:6001; OMIM: 602856; Uniprot ID:RGS10_HUMAN; ENSEMBL ID: ENSG00000148908; HGNC ID: 9992 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.501200
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 24 / 564012 | 42 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 55 / 1939121 | 28 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 |  |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 5 / 106883 | 46 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 88 / 3360307 | 26 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 6 / 124949 | 48 | |
| soft tissue/muscle tissue tumor | 8 / 125191 | 63 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 3 / 123478 | 24 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 13 / 1100989 | 11 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 5 / 211054 | 23 | |
| heart | 11 / 89626 | 122 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 19 / 336974 | 56 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 18 / 91610 | 196 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 6 / 210574 | 28 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 0 / 330442 | 0 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204316_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.25 | |
| Adipocyte | 4.7 | |
| AdrenalCortex | 5.1 | |
| Adrenalgland | 4.05 | |
| Amygdala | 4.95 | |
| Appendix | 4.85 | |
| AtrioventricularNode | 3.7 | |
| BDCA4+_DentriticCells | 5.55 | |
| Bonemarrow | 5.3 | |
| BronchialEpithelialCells | 4.8 | |
| CD105+_Endothelial | 6 | |
| CD14+_Monocytes | 6.1 | |
| CD19+_BCells(neg._sel.) | 5.3 | |
| CD33+_Myeloid | 6.95 | |
| CD34+ | 6.3 | |
| CD4+_Tcells | 5.4 | |
| CD56+_NKCells | 5.85 | |
| CD71+_EarlyErythroid | 4.65 | |
| CD8+_Tcells | 6.6 | |
| CardiacMyocytes | 6.05 | |
| Caudatenucleus | 4.3 | |
| Cerebellum | 3.9 | |
| CerebellumPeduncles | 5.45 | |
| CiliaryGanglion | 3.45 | |
| CingulateCortex | 4.9 | |
| Colorectaladenocarcinoma | 4.8 | |
| DorsalRootGanglion | 3.65 | |
| FetalThyroid | 5.1 | |
| Fetalbrain | 4.7 | |
| Fetalliver | 4.3 | |
| Fetallung | 4 | |
| GlobusPallidus | 3.5 | |
| Heart | 6.05 | |
| Hypothalamus | 5.3 | |
| Kidney | 3.9 | |
| Leukemia_chronicMyelogenousK-562 | 4.4 | |
| Leukemia_promyelocytic-HL-60 | 4.35 | |
| Leukemialymphoblastic(MOLT-4) | 3.9 | |
| Liver | 6.35 | |
| Lung | 5.35 | |
| Lymphnode | 4.35 | |
| Lymphoma_burkitts(Daudi) | 6.35 | |
| Lymphoma_burkitts(Raji) | 7.1 | |
| MedullaOblongata | 4.4 | |
| OccipitalLobe | 4.35 | |
| OlfactoryBulb | 3.8 | |
| Ovary | 3.15 | |
| Pancreas | 3.9 | |
| PancreaticIslet | 5.15 | |
| ParietalLobe | 5.05 | |
| Pituitary | 5.6 | |
| Placenta | 4.95 | |
| Pons | 4.6 | |
| PrefrontalCortex | 5.85 | |
| Prostate | 5.7 | |
| Salivarygland | 3.8 | |
| SkeletalMuscle | 5.7 | |
| Skin | 3.75 | |
| SmoothMuscle | 5.55 | |
| Spinalcord | 5.2 | |
| SubthalamicNucleus | 4.35 | |
| SuperiorCervicalGanglion | 7.3 | |
| TemporalLobe | 4.4 | |
| Testis | 4.05 | |
| TestisGermCell | 4.1 | |
| TestisIntersitial | 4 | |
| TestisLeydigCell | 4.8 | |
| TestisSeminiferousTubule | 4.15 | |
| Thalamus | 4.9 | |
| Thymus | 3.9 | |
| Thyroid | 6.15 | |
| Tongue | 4.7 | |
| Tonsil | 4.7 | |
| Trachea | 4.05 | |
| TrigeminalGanglion | 4.85 | |
| Uterus | 4 | |
| UterusCorpus | 4.3 | |
| WholeBlood | 5.4 | |
| Wholebrain | 4.05 | |
| colon | 4.85 | |
| pineal_day | 5.96 | |
| pineal_night | 5.82 | |
| retina | 5.8 | |
| small_intestine | 4.7 | |
- Probe name: CUST_5055_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.02 ± 0.64 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.07 ± 0.65 | |
| Basal Part of Pons | 4.84 ± 0.63 | |
| Cerebellar Cortex | 3.53 ± 0.54 | |
| Cerebellar Nuclei | 5.34 ± 0.52 | |
| Claustrum | 3.48 ± 0.98 | |
| Epithalamus | 5.14 ± 0.6 | |
| Frontal Lobe | 4.06 ± 0.69 | |
| Globus Pallidus | 5.83 ± 0.46 | |
| Hypothalamus | 3.89 ± 1.27 | |
| Insula | 3.87 ± 0.61 | |
| Limbic Lobe | 3.74 ± 0.85 | |
| Mesencephalon | 3.96 ± 0.93 | |
| Myelencephalon | 3.94 ± 0.87 | |
| Occipital Lobe | 3.36 ± 0.79 | |
| Parietal Lobe | 3.99 ± 0.83 | |
| Pontine Tegmentum | 3.81 ± 0.75 | |
| Striatum | 4.42 ± 0.64 | |
| Subthalamus | 4.55 ± 0.25 | |
| Temporal Lobe | 4.12 ± 0.76 | |
| Thalamus | 3.87 ± 0.71 | |
| White Matter | 5.21 ± 0.48 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Rgs10 | CB | Cerebellum | 30 | |
| 51.56 | | |||
| Rgs10 | CTX | Cerebral cortex | 27.27 | |
| 23.12 | | |||
| Rgs10 | HIP | Hippocampal region | 23.15 | |
| 35.86 | | |||
| Rgs10 | HPF | Hippocampal formation | 22.03 | |
| 28.43 | | |||
| Rgs10 | HY | Hypothalamus | 44.78 | |
| 46.96 | | |||
| Rgs10 | LSX | Lateral septal complex | 65.95 | |
| 66.28 | | |||
| Rgs10 | MB | Midbrain | 39.96 | |
| 43.83 | | |||
| Rgs10 | MY | Medulla | 50.05 | |
| 62.75 | | |||
| Rgs10 | OLF | Olfactory bulb | 36.02 | |
| 31.96 | | |||
| Rgs10 | P | Pons | 37.21 | |
| 43.03 | | |||
| Rgs10 | PAL | Pallidum | 48.09 | |
| 58.31 | | |||
| Rgs10 | RHP | Retrohippocampal region | 21.44 | |
| 20.3 | | |||
| Rgs10 | sAMY | Striatum-like amygdalar nuclei | 24.02 | |
| 21.5 | | |||
| Rgs10 | STR | Striatum | 33.54 | |
| 29.76 | | |||
| Rgs10 | STRd | Striatum dorsal region | 27.61 | |
| 24.54 | | |||
| Rgs10 | STRv | Striatum ventral region | 46.33 | |
| 37.73 | | |||
| Rgs10 | TH | Thalamus | 10.84 | |
| 12.11 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00486841 | 10 | 130 | 139 | LQDQIFNLMK | Peptide Atlas |
| RGS10_HUMAN_0 | 0 | 0 | 0 | LQDQIFNLMK | PRIDE |
| RGS10_HUMAN_0 | 0 | 0 | 0 | TEEEEEDLPDAQTAAK | PRIDE |
| RGS10_HUMAN_109 | 12 | 109 | 120 | ILEEPHPLMFQK | PRIDE |
| RGS10_HUMAN_121 | 10 | 121 | 130 | LQDQIFNLMK | PRIDE |
| RGS10_HUMAN_122 | 10 | 122 | 131 | LQDQIFNLMK | PRIDE |
| RGS10_HUMAN_148 | 17 | 148 | 164 | RTEEEEEDLPDAQTAAK | PRIDE |
| RGS10_HUMAN_149 | 16 | 149 | 164 | TEEEEEDLPDAQTAAK | PRIDE |
| RGS10_HUMAN_149 | 17 | 149 | 165 | TEEEEEDLPDAQTAAKR | PRIDE |
| RGS10_HUMAN_29 | 17 | 29 | 45 | WAASLENLLEDPEGVKR | PRIDE |