AutismKB 2.0

Annotation Detail for MIIP


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MIIP ( FLJ12438,FLJ38609,IIP45 )
Gene Full Name: migration and invasion inhibitory protein
Band: 1p36.22
Quick LinksEntrez ID:60672; OMIM: 608772; Uniprot ID:MIIP_HUMAN; ENSEMBL ID: ENSG00000116691; HGNC ID: 25715
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus27 / 56401247
neonate2 / 3109764
infant1 / 2362042
juvenile5 / 5555689
adult90 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor10 / 11936983
germ cell tumor26 / 26384598
glioma6 / 10688356
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia13 / 95842135
liver tumor4 / 9635941
lung tumor11 / 103127106
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal198 / 336030758
ovarian tumor5 / 7668265
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma10 / 46356215
skin tumor18 / 124949144
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites7 / 40015174
bladder2 / 2975767
blood17 / 123478137
bone0 / 716550 
bone marrow6 / 48801122
brain68 / 110098961
cervix11 / 48171228
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye21 / 21105499
heart6 / 8962666
intestine12 / 23447251
kidney5 / 21177723
larynx0 / 241450 
liver9 / 20774343
lung16 / 33697447
lymph1 / 4427022
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary10 / 10205197
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta15 / 28082553
prostate6 / 18934531
salivary gland0 / 201550 
skin22 / 210574104
spleen12 / 53952222
stomach5 / 9661951
testis26 / 33044278
thymus9 / 81131110
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus16 / 23287868
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 48659_at
Cell line Expression level Expression bar
721_B_lymphoblasts35.8
Adipocyte14.9
AdrenalCortex11.35
Adrenalgland8.3
Amygdala11.2
Appendix23.35
AtrioventricularNode7.05
BDCA4+_DentriticCells60.45
Bonemarrow31.15
BronchialEpithelialCells21.3
CD105+_Endothelial15.35
CD14+_Monocytes34.05
CD19+_BCells(neg._sel.)29.15
CD33+_Myeloid44.65
CD34+18.85
CD4+_Tcells17.15
CD56+_NKCells18.9
CD71+_EarlyErythroid12.85
CD8+_Tcells11.5
CardiacMyocytes16
Caudatenucleus9.55
Cerebellum9.35
CerebellumPeduncles15.1
CiliaryGanglion6.05
CingulateCortex11.15
Colorectaladenocarcinoma34.9
DorsalRootGanglion7.35
FetalThyroid13.5
Fetalbrain15.25
Fetalliver20.15
Fetallung14.5
GlobusPallidus6.95
Heart36
Hypothalamus12.55
Kidney8.35
Leukemia_chronicMyelogenousK-562174.5
Leukemia_promyelocytic-HL-6045.1
Leukemialymphoblastic(MOLT-4)39.95
Liver17.6
Lung32.1
Lymphnode19.95
Lymphoma_burkitts(Daudi)21.3
Lymphoma_burkitts(Raji)96.4
MedullaOblongata8.85
OccipitalLobe8.5
OlfactoryBulb10.7
Ovary7.15
Pancreas10.6
PancreaticIslet13.95
ParietalLobe12.5
Pituitary14.3
Placenta11.85
Pons9.85
PrefrontalCortex11.95
Prostate16.85
Salivarygland7.9
SkeletalMuscle24.6
Skin7.55
SmoothMuscle13.35
Spinalcord17.85
SubthalamicNucleus9.3
SuperiorCervicalGanglion10.6
TemporalLobe9.65
Testis21.75
TestisGermCell19.85
TestisIntersitial9.4
TestisLeydigCell9.3
TestisSeminiferousTubule18.95
Thalamus9.85
Thymus17.25
Thyroid21
Tongue9.9
Tonsil12.45
Trachea8.3
TrigeminalGanglion9.4
Uterus20.95
UterusCorpus26.85
WholeBlood32.45
Wholebrain14.5
colon9.4
pineal_day6.94
pineal_night8.54
retina12.775
small_intestine9.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15409_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.71 ± 0.57
Basal Forebrain2.96 ± 0.8
Basal Part of Pons3.81 ± 0.56
Cerebellar Cortex3.83 ± 0.5
Cerebellar Nuclei3.54 ± 0.5
Claustrum3.42 ± 0.8
Epithalamus3.68 ± 0.24
Frontal Lobe3.67 ± 0.56
Globus Pallidus3.59 ± 0.55
Hypothalamus3.31 ± 0.43
Insula3.76 ± 0.33
Limbic Lobe3.47 ± 0.63
Mesencephalon3.52 ± 0.55
Myelencephalon3.65 ± 0.55
Occipital Lobe3.16 ± 0.69
Parietal Lobe3.48 ± 0.5
Pontine Tegmentum3.57 ± 0.65
Striatum3.38 ± 0.62
Subthalamus3.58 ± 0.33
Temporal Lobe3.6 ± 0.58
Thalamus3.59 ± 0.55
White Matter3.71 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D4Wsu114eCBCerebellum68.04
91.43
D4Wsu114eCTXCerebral cortex100
88.42
D4Wsu114eHIPHippocampal region68.67
96.14
D4Wsu114eHPFHippocampal formation91.97
100
D4Wsu114eHYHypothalamus62.62
52.37
D4Wsu114eLSXLateral septal complex68.53
46.71
D4Wsu114eMBMidbrain66.87
63.79
D4Wsu114eMYMedulla67.23
78.27
D4Wsu114eOLFOlfactory bulb100
97.01
D4Wsu114ePPons64.59
71.65
D4Wsu114ePALPallidum70.69
64.99
D4Wsu114eRHPRetrohippocampal region100
100
D4Wsu114esAMYStriatum-like amygdalar nuclei93.78
68.88
D4Wsu114eSTRStriatum85.01
63.19
D4Wsu114eSTRdStriatum dorsal region89.67
67.32
D4Wsu114eSTRvStriatum ventral region79.01
59.05
D4Wsu114eTHThalamus75.59
70.03
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018