AutismKB 2.0

Annotation Detail for TNFRSF17


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Basic Information Top
Gene Symbol:TNFRSF17 ( BCM,BCMA,CD269 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 17
Band: 16p13.13
Quick LinksEntrez ID:608; OMIM: 109545; Uniprot ID:TNR17_HUMAN; ENSEMBL ID: ENSG00000048462; HGNC ID: 11913
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206641_at
Cell line Expression level Expression bar
721_B_lymphoblasts170
Adipocyte3.8
AdrenalCortex4.1
Adrenalgland3.25
Amygdala4.1
Appendix4.05
AtrioventricularNode3.05
BDCA4+_DentriticCells435.25
Bonemarrow4
BronchialEpithelialCells3.75
CD105+_Endothelial3.85
CD14+_Monocytes4.15
CD19+_BCells(neg._sel.)185.15
CD33+_Myeloid4.9
CD34+5.95
CD4+_Tcells4.15
CD56+_NKCells19.7
CD71+_EarlyErythroid3.65
CD8+_Tcells3.7
CardiacMyocytes5.05
Caudatenucleus3.45
Cerebellum3.1
CerebellumPeduncles4.4
CiliaryGanglion2.8
CingulateCortex3.95
Colorectaladenocarcinoma3.9
DorsalRootGanglion3
FetalThyroid3.75
Fetalbrain3.75
Fetalliver3.35
Fetallung3.15
GlobusPallidus2.85
Heart5.1
Hypothalamus4.15
Kidney3.05
Leukemia_chronicMyelogenousK-5623.45
Leukemia_promyelocytic-HL-603.4
Leukemialymphoblastic(MOLT-4)3.1
Liver5.2
Lung4.2
Lymphnode6.4
Lymphoma_burkitts(Daudi)5.5
Lymphoma_burkitts(Raji)5.55
MedullaOblongata3.5
OccipitalLobe3.45
OlfactoryBulb3
Ovary2.6
Pancreas3.1
PancreaticIslet4.1
ParietalLobe4.1
Pituitary4.45
Placenta3.95
Pons3.7
PrefrontalCortex4.75
Prostate4.5
Salivarygland3.25
SkeletalMuscle4.55
Skin3.1
SmoothMuscle4.35
Spinalcord4.05
SubthalamicNucleus3.55
SuperiorCervicalGanglion4.8
TemporalLobe3.55
Testis3.3
TestisGermCell3.2
TestisIntersitial3.25
TestisLeydigCell3.8
TestisSeminiferousTubule3.25
Thalamus3.9
Thymus3.35
Thyroid4.85
Tongue3.8
Tonsil4.25
Trachea3.3
TrigeminalGanglion4.2
Uterus3.1
UterusCorpus3.5
WholeBlood4.2
Wholebrain3.25
colon6.7
pineal_day4.82
pineal_night4.72
retina4.625
small_intestine40.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P37736
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.25 ± 1.13
Basal Forebrain1.82 ± 0.22
Basal Part of Pons1.48 ± 0.46
Cerebellar Cortex1.31 ± 0.38
Cerebellar Nuclei2.04 ± 0.72
Claustrum2.45 ± 0.68
Epithalamus1.48 ± 0.95
Frontal Lobe1.58 ± 0.76
Globus Pallidus2.17 ± 0.52
Hypothalamus1.92 ± 0.81
Insula1.6 ± 0.47
Limbic Lobe1.73 ± 0.67
Mesencephalon2.05 ± 0.87
Myelencephalon1.9 ± 0.84
Occipital Lobe1.99 ± 0.93
Parietal Lobe1.78 ± 0.69
Pontine Tegmentum1.92 ± 0.84
Striatum4.37 ± 0.99
Subthalamus2.06 ± 0.86
Temporal Lobe1.56 ± 0.47
Thalamus1.79 ± 0.69
White Matter2.04 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tnfrsf17CBCerebellum7.02
7.75
Tnfrsf17CTXCerebral cortex7.23
4.86
Tnfrsf17HIPHippocampal region9.53
8.9
Tnfrsf17HPFHippocampal formation10.77
8.95
Tnfrsf17HYHypothalamus7.79
5.93
Tnfrsf17LSXLateral septal complex0.7
0.53
Tnfrsf17MBMidbrain5.6
5
Tnfrsf17MYMedulla4.32
5.7
Tnfrsf17OLFOlfactory bulb10.56
7.61
Tnfrsf17PPons7.5
8.87
Tnfrsf17PALPallidum5.91
4.57
Tnfrsf17RHPRetrohippocampal region13.86
9.54
Tnfrsf17sAMYStriatum-like amygdalar nuclei6.92
4.87
Tnfrsf17STRStriatum5.77
4.11
Tnfrsf17STRdStriatum dorsal region4.37
3.3
Tnfrsf17STRvStriatum ventral region12.83
8.11
Tnfrsf17THThalamus7.43
5.43
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018