Annotation Detail for BCR
Basic Information Top
| Gene Symbol: | BCR ( ALL,BCR1,CML,D22S11,D22S662,FLJ16453,PHL ) |
|---|---|
| Gene Full Name: | breakpoint cluster region |
| Band: | 22q11.23 |
| Quick Links | Entrez ID:613; OMIM: 151410; Uniprot ID:BCR_HUMAN; ENSEMBL ID: ENSG00000186716; HGNC ID: 1014 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.715409
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 24 / 564012 | 42 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 131 / 1939121 | 67 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 1 / 1939121 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 4 / 82823 | 48 | |
| colorectal tumor | 11 / 114246 | 96 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 16 / 263845 | 60 | |
| glioma | 21 / 106883 | 196 | |
| head and neck tumor | 6 / 136302 | 44 | |
| kidney tumor | 6 / 68959 | 87 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 11 / 103127 | 106 | |
| lymphoma | 16 / 71755 | 222 |  |
| non-neoplasia | 7 / 97250 | 71 | |
| normal | 203 / 3360307 | 60 | |
| ovarian tumor | 8 / 76682 | 104 | |
| pancreatic tumor | 19 / 104616 | 181 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 4 / 46356 | 86 | |
| skin tumor | 21 / 124949 | 168 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 8 / 90257 | 88 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 |  |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 0 / 3360307 | 0 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 6 / 40015 | 149 | |
| bladder | 1 / 29757 | 33 | |
| blood | 5 / 123478 | 40 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 78 / 1100989 | 70 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 17 / 211054 | 80 | |
| heart | 1 / 89626 | 11 | |
| intestine | 17 / 234472 | 72 | |
| kidney | 13 / 211777 | 61 | |
| larynx | 1 / 24145 | 41 | |
| liver | 6 / 207743 | 28 | |
| lung | 22 / 336974 | 65 | |
| lymph | 8 / 44270 | 180 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 12 / 153271 | 78 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 9 / 102051 | 88 | |
| pancreas | 21 / 214812 | 97 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 23 / 280825 | 81 | |
| prostate | 7 / 189345 | 36 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 28 / 210574 | 132 | |
| spleen | 6 / 53952 | 111 | |
| stomach | 2 / 96619 | 20 | |
| testis | 13 / 330442 | 39 | |
| thymus | 6 / 81131 | 73 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 4 / 13680 | 292 | |
| uterus | 15 / 232878 | 64 | |
| vascular | 5 / 51780 | 96 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 217223_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.65 | |
| Adipocyte | 3.7 | |
| AdrenalCortex | 3.85 | |
| Adrenalgland | 3.15 | |
| Amygdala | 4.8 | |
| Appendix | 3.75 | |
| AtrioventricularNode | 2.8 | |
| BDCA4+_DentriticCells | 4.1 | |
| Bonemarrow | 3.65 | |
| BronchialEpithelialCells | 3.65 | |
| CD105+_Endothelial | 3.75 | |
| CD14+_Monocytes | 4 | |
| CD19+_BCells(neg._sel.) | 4 | |
| CD33+_Myeloid | 4.75 | |
| CD34+ | 4.85 | |
| CD4+_Tcells | 4.15 | |
| CD56+_NKCells | 4.5 | |
| CD71+_EarlyErythroid | 3.45 | |
| CD8+_Tcells | 3.65 | |
| CardiacMyocytes | 4.6 | |
| Caudatenucleus | 7.65 | |
| Cerebellum | 3.05 | |
| CerebellumPeduncles | 4.2 | |
| CiliaryGanglion | 2.65 | |
| CingulateCortex | 3.8 | |
| Colorectaladenocarcinoma | 3.7 | |
| DorsalRootGanglion | 2.8 | |
| FetalThyroid | 3.65 | |
| Fetalbrain | 3.75 | |
| Fetalliver | 3.2 | |
| Fetallung | 3.15 | |
| GlobusPallidus | 2.75 | |
| Heart | 4.75 | |
| Hypothalamus | 4.15 | |
| Kidney | 3.05 | |
| Leukemia_chronicMyelogenousK-562 | 3.35 | |
| Leukemia_promyelocytic-HL-60 | 3.3 | |
| Leukemialymphoblastic(MOLT-4) | 3 | |
| Liver | 4.9 | |
| Lung | 4.1 | |
| Lymphnode | 3.25 | |
| Lymphoma_burkitts(Daudi) | 4.75 | |
| Lymphoma_burkitts(Raji) | 5.15 | |
| MedullaOblongata | 3.45 | |
| OccipitalLobe | 3.35 | |
| OlfactoryBulb | 2.95 | |
| Ovary | 2.45 | |
| Pancreas | 2.95 | |
| PancreaticIslet | 4 | |
| ParietalLobe | 3.9 | |
| Pituitary | 4.35 | |
| Placenta | 5.8 | |
| Pons | 3.55 | |
| PrefrontalCortex | 6.25 | |
| Prostate | 4.4 | |
| Salivarygland | 2.95 | |
| SkeletalMuscle | 4.3 | |
| Skin | 2.85 | |
| SmoothMuscle | 4.25 | |
| Spinalcord | 4.05 | |
| SubthalamicNucleus | 3.4 | |
| SuperiorCervicalGanglion | 4.15 | |
| TemporalLobe | 3.4 | |
| Testis | 3.8 | |
| TestisGermCell | 3.2 | |
| TestisIntersitial | 3.1 | |
| TestisLeydigCell | 3.65 | |
| TestisSeminiferousTubule | 3.75 | |
| Thalamus | 3.8 | |
| Thymus | 3.25 | |
| Thyroid | 4.75 | |
| Tongue | 3.6 | |
| Tonsil | 3.6 | |
| Trachea | 3.1 | |
| TrigeminalGanglion | 3.6 | |
| Uterus | 3.05 | |
| UterusCorpus | 3.3 | |
| WholeBlood | 4.05 | |
| Wholebrain | 3.35 | |
| colon | 3.7 | |
| pineal_day | 4.72 | |
| pineal_night | 4.6 | |
| retina | 4.5 | |
| small_intestine | 3.6 | |
- Probe name: A_24_P459963
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.73 ± 1.11 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.38 ± 0.37 | |
| Basal Part of Pons | 1.94 ± 0.41 | |
| Cerebellar Cortex | 2.06 ± 0.68 | |
| Cerebellar Nuclei | 2.39 ± 0.66 | |
| Claustrum | 3.15 ± 0.85 | |
| Epithalamus | 2.08 ± 0.79 | |
| Frontal Lobe | 2.16 ± 0.69 | |
| Globus Pallidus | 2.72 ± 0.55 | |
| Hypothalamus | 2.27 ± 0.8 | |
| Insula | 2.19 ± 1.18 | |
| Limbic Lobe | 2.24 ± 0.7 | |
| Mesencephalon | 2.48 ± 0.79 | |
| Myelencephalon | 2.31 ± 0.68 | |
| Occipital Lobe | 2.38 ± 0.78 | |
| Parietal Lobe | 2.22 ± 0.79 | |
| Pontine Tegmentum | 2.33 ± 0.78 | |
| Striatum | 2.92 ± 0.77 | |
| Subthalamus | 2.37 ± 0.7 | |
| Temporal Lobe | 2.14 ± 0.68 | |
| Thalamus | 2.25 ± 0.64 | |
| White Matter | 2.27 ± 0.2 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Bcr | CB | Cerebellum | 4.89 | |
| 5.24 | | |||
| Bcr | CTX | Cerebral cortex | 11.88 | |
| 8.08 | | |||
| Bcr | HIP | Hippocampal region | 7.74 | |
| 7.46 | | |||
| Bcr | HPF | Hippocampal formation | 8.53 | |
| 7.19 | | |||
| Bcr | HY | Hypothalamus | 4.55 | |
| 3.03 | | |||
| Bcr | LSX | Lateral septal complex | 1.85 | |
| 1.66 | | |||
| Bcr | MB | Midbrain | 2.78 | |
| 2.74 | | |||
| Bcr | MY | Medulla | 7.39 | |
| 7.89 | | |||
| Bcr | OLF | Olfactory bulb | 12.06 | |
| 9.27 | | |||
| Bcr | P | Pons | 6.15 | |
| 6.14 | | |||
| Bcr | PAL | Pallidum | 9.52 | |
| 8.09 | | |||
| Bcr | RHP | Retrohippocampal region | 9.98 | |
| 6.91 | | |||
| Bcr | sAMY | Striatum-like amygdalar nuclei | 9.4 | |
| 6.06 | | |||
| Bcr | STR | Striatum | 37.62 | |
| 26.89 | | |||
| Bcr | STRd | Striatum dorsal region | 47.1 | |
| 33.9 | | |||
| Bcr | STRv | Striatum ventral region | 39.85 | |
| 27.84 | | |||
| Bcr | TH | Thalamus | 2.53 | |
| 1.95 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| BCR_HUMAN_1073 | 9 | 1073 | 1081 | QCVEEIERR | PRIDE |
| BCR_HUMAN_91 | 34 | 91 | 124 | ASASRPQPAPADGADPPPAEEPEARPDGEGSPGK | PRIDE |
| PAp00040805 | 17 | 392 | 408 | HRHCPVVVSEATIVGVR | Peptide Atlas |