AutismKB 2.0

Annotation Detail for RPL37


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Basic Information Top
Gene Symbol:RPL37 ( DKFZp686G1699,MGC99572 )
Gene Full Name: ribosomal protein L37
Band: 5p13.1
Quick LinksEntrez ID:6167; OMIM: 604181; Uniprot ID:RL37_HUMAN; ENSEMBL ID: ENSG00000145592; HGNC ID: 10347
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst36 / 62319577
fetus395 / 564012700
neonate14 / 31097450
infant2 / 2362084
juvenile8 / 55556143
adult698 / 1939121359
embryoid body27 / 70761381
blastocyst90 / 623191444
fetus92 / 564012163
neonate5 / 31097160
infant5 / 23620211
juvenile4 / 5555671
adult332 / 1939121171
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor6 / 34366174
chondrosarcoma4 / 8282348
colorectal tumor21 / 114246183
esophageal tumor4 / 17290231
gastrointestinal tumor14 / 119369117
germ cell tumor45 / 263845170
glioma28 / 106883261
head and neck tumor27 / 136302198
kidney tumor10 / 68959145
leukemia18 / 95842187
liver tumor13 / 96359134
lung tumor13 / 103127126
lymphoma8 / 71755111
non-neoplasia6 / 9725061
normal1089 / 3360307324
ovarian tumor14 / 76682182
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS23 / 125680183
prostate cancer302 / 1026802941
retinoblastoma11 / 46356237
skin tumor10 / 12494980
soft tissue/muscle tissue tumor27 / 125191215
uterine tumor7 / 9025777
adrenal tumor4 / 12794312
bladder carcinoma0 / 174750 
breast (mammary gland) tumor15 / 94178159
cervical tumor6 / 34366174
chondrosarcoma2 / 8282324
colorectal tumor17 / 114246148
esophageal tumor0 / 172900 
gastrointestinal tumor21 / 119369175
germ cell tumor17 / 26384564
glioma13 / 106883121
head and neck tumor5 / 13630236
kidney tumor15 / 68959217
leukemia12 / 95842125
liver tumor28 / 96359290
lung tumor20 / 103127193
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal831 / 3360307247
ovarian tumor16 / 76682208
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer56 / 102680545
retinoblastoma0 / 463560 
skin tumor10 / 12494980
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland2 / 3319760
ascites7 / 40015174
bladder1 / 2975733
blood187 / 1234781514
bone25 / 71655348
bone marrow41 / 48801840
brain173 / 1100989157
cervix7 / 48171145
connective tissue12 / 14925580
ear9 / 16212555
embryonic tissue119 / 215722551
esophagus4 / 20209197
eye27 / 211054127
heart60 / 89626669
intestine51 / 234472217
kidney35 / 211777165
larynx14 / 24145579
liver46 / 207743221
lung56 / 336974166
lymph3 / 4427067
lymph node12 / 91610130
mammary gland21 / 153271137
mouth9 / 67052134
muscle75 / 107715696
nerve1 / 1576863
ovary27 / 102051264
pancreas33 / 214812153
parathyroid17 / 20539827
pharynx10 / 41328241
pituitary gland2 / 16585120
placenta16 / 28082556
prostate345 / 1893451822
salivary gland1 / 2015549
skin48 / 210574227
spleen10 / 53952185
stomach13 / 96619134
testis26 / 33044278
thymus14 / 81131172
thyroid5 / 47473105
tonsil2 / 16999117
trachea4 / 5241376
umbilical cord10 / 13680730
uterus25 / 232878107
vascular36 / 51780695
adipose tissue3 / 13106228
adrenal gland7 / 33197210
ascites12 / 40015299
bladder0 / 297570 
blood88 / 123478712
bone25 / 71655348
bone marrow41 / 48801840
brain40 / 110098936
cervix6 / 48171124
connective tissue4 / 14925526
ear7 / 16212431
embryonic tissue311 / 2157221441
esophagus0 / 202090 
eye18 / 21105485
heart14 / 89626156
intestine33 / 234472140
kidney17 / 21177780
larynx0 / 241450 
liver54 / 207743259
lung50 / 336974148
lymph2 / 4427045
lymph node1 / 9161010
mammary gland16 / 153271104
mouth5 / 6705274
muscle170 / 1077151578
nerve1 / 1576863
ovary21 / 102051205
pancreas18 / 21481283
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland7 / 16585422
placenta4 / 28082514
prostate79 / 189345417
salivary gland1 / 2015549
skin17 / 21057480
spleen1 / 5395218
stomach23 / 96619238
testis10 / 33044230
thymus4 / 8113149
thyroid1 / 4747321
tonsil5 / 16999294
trachea0 / 524130 
umbilical cord5 / 13680365
uterus9 / 23287838
vascular12 / 51780231
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200092_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5899.75
Adipocyte3707.45
AdrenalCortex2785
Adrenalgland2152.9
Amygdala1964.95
Appendix3224.4
AtrioventricularNode1163.45
BDCA4+_DentriticCells6035.35
Bonemarrow2936.25
BronchialEpithelialCells6097.65
CD105+_Endothelial5840.9
CD14+_Monocytes4968.3
CD19+_BCells(neg._sel.)7846.9
CD33+_Myeloid5031.55
CD34+7699.65
CD4+_Tcells7481.9
CD56+_NKCells6842.7
CD71+_EarlyErythroid2250.3
CD8+_Tcells6614.35
CardiacMyocytes4085.45
Caudatenucleus1496.6
Cerebellum1295.75
CerebellumPeduncles2442.8
CiliaryGanglion842
CingulateCortex1563.05
Colorectaladenocarcinoma2499.3
DorsalRootGanglion1292.2
FetalThyroid3122.4
Fetalbrain3032.5
Fetalliver2428.5
Fetallung3498.05
GlobusPallidus730.3
Heart2465.15
Hypothalamus2492.65
Kidney1532.9
Leukemia_chronicMyelogenousK-5627046.3
Leukemia_promyelocytic-HL-605344.6
Leukemialymphoblastic(MOLT-4)4778.4
Liver2667.95
Lung3805.15
Lymphnode5494.3
Lymphoma_burkitts(Daudi)7562.95
Lymphoma_burkitts(Raji)5657
MedullaOblongata1371.6
OccipitalLobe1217.85
OlfactoryBulb3152.4
Ovary3814
Pancreas2926.15
PancreaticIslet3979.6
ParietalLobe1014.45
Pituitary2589.35
Placenta2172.45
Pons1064.9
PrefrontalCortex2953
Prostate4012.5
Salivarygland3344.7
SkeletalMuscle1765.6
Skin2376.7
SmoothMuscle5510.9
Spinalcord2834.95
SubthalamicNucleus1112.05
SuperiorCervicalGanglion850.2
TemporalLobe1746.7
Testis1922.65
TestisGermCell2597.95
TestisIntersitial1963.5
TestisLeydigCell1633.75
TestisSeminiferousTubule1770.9
Thalamus1741.45
Thymus4202.75
Thyroid3867.6
Tongue3183.8
Tonsil3779.7
Trachea2505.8
TrigeminalGanglion1032.05
Uterus4596.2
UterusCorpus2908.8
WholeBlood6324.95
Wholebrain2329.1
colon4940.8
pineal_day1844.02
pineal_night1868.82
retina3793.2
small_intestine5729.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P196411
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.64 ± 0.42
Basal Forebrain5.98 ± 0.23
Basal Part of Pons5.65 ± 0.4
Cerebellar Cortex6 ± 0.26
Cerebellar Nuclei5.75 ± 0.46
Claustrum5.3 ± 0.59
Epithalamus5.62 ± 0.43
Frontal Lobe5.69 ± 0.4
Globus Pallidus6.26 ± 0.26
Hypothalamus6.04 ± 0.32
Insula5.79 ± 0.23
Limbic Lobe5.57 ± 0.39
Mesencephalon5.82 ± 0.51
Myelencephalon5.74 ± 0.4
Occipital Lobe5.55 ± 0.4
Parietal Lobe5.65 ± 0.37
Pontine Tegmentum5.73 ± 0.44
Striatum5.79 ± 0.42
Subthalamus5.78 ± 0.16
Temporal Lobe5.76 ± 0.36
Thalamus5.78 ± 0.39
White Matter6.61 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rpl37CBCerebellum6.76
7.62
Rpl37CTXCerebral cortex5.05
3.49
Rpl37HIPHippocampal region3.16
3.47
Rpl37HPFHippocampal formation3.4
3.29
Rpl37HYHypothalamus1.2
1.01
Rpl37LSXLateral septal complex0.22
0.17
Rpl37MBMidbrain4.03
4.73
Rpl37MYMedulla7.54
7.4
Rpl37OLFOlfactory bulb11.23
9.85
Rpl37PPons6.87
7.36
Rpl37PALPallidum2.14
1.77
Rpl37RHPRetrohippocampal region3.81
3.01
Rpl37sAMYStriatum-like amygdalar nuclei0.61
1.24
Rpl37STRStriatum2.97
2.51
Rpl37STRdStriatum dorsal region3.02
2.67
Rpl37STRvStriatum ventral region4.74
3.08
Rpl37THThalamus3.41
3.16
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00005844 8 13 20 NKTHTLCR Peptide Atlas
RL37_HUMAN_1 10 1 10 TKGTSSFGKR PRIDE
RL37_HUMAN_1 11 1 11 MTKGTSSFGKR PRIDE
RL37_HUMAN_2 10 2 11 TKGTSSFGKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018