AutismKB 2.0

Annotation Detail for RPLP1


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Basic Information Top
Gene Symbol:RPLP1 ( FLJ27448,MGC5215,P1,RPP1 )
Gene Full Name: ribosomal protein, large, P1
Band: 15q23
Quick LinksEntrez ID:6176; OMIM: 180520; Uniprot ID:RLA1_HUMAN; ENSEMBL ID: ENSG00000137818; HGNC ID: 10372
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body55 / 70761777
blastocyst82 / 623191315
fetus165 / 564012292
neonate26 / 31097836
infant5 / 23620211
juvenile23 / 55556413
adult908 / 1939121468
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor11 / 12794859
bladder carcinoma14 / 17475801
breast (mammary gland) tumor49 / 94178520
cervical tumor14 / 34366407
chondrosarcoma13 / 82823156
colorectal tumor54 / 114246472
esophageal tumor10 / 17290578
gastrointestinal tumor97 / 119369812
germ cell tumor71 / 263845269
glioma34 / 106883318
head and neck tumor28 / 136302205
kidney tumor55 / 68959797
leukemia63 / 95842657
liver tumor29 / 96359300
lung tumor63 / 103127610
lymphoma45 / 71755627
non-neoplasia12 / 97250123
normal1506 / 3360307448
ovarian tumor19 / 76682247
pancreatic tumor181 / 1046161730
primitive neuroectodermal tumor of the CNS37 / 125680294
prostate cancer164 / 1026801597
retinoblastoma49 / 463561057
skin tumor69 / 124949552
soft tissue/muscle tissue tumor49 / 125191391
uterine tumor41 / 90257454
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue9 / 13106686
adrenal gland20 / 33197602
ascites56 / 400151399
bladder19 / 29757638
blood57 / 123478461
bone35 / 71655488
bone marrow82 / 488011680
brain166 / 1100989150
cervix23 / 48171477
connective tissue22 / 149255147
ear5 / 16212308
embryonic tissue313 / 2157221450
esophagus10 / 20209494
eye123 / 211054582
heart119 / 896261327
intestine98 / 234472417
kidney73 / 211777344
larynx9 / 24145372
liver121 / 207743582
lung98 / 336974290
lymph25 / 44270564
lymph node33 / 91610360
mammary gland63 / 153271411
mouth13 / 67052193
muscle161 / 1077151494
nerve2 / 15768126
ovary34 / 102051333
pancreas203 / 214812945
parathyroid4 / 20539194
pharynx23 / 41328556
pituitary gland12 / 16585723
placenta73 / 280825259
prostate229 / 1893451209
salivary gland23 / 201551141
skin100 / 210574474
spleen15 / 53952278
stomach36 / 96619372
testis34 / 330442102
thymus11 / 81131135
thyroid7 / 47473147
tonsil13 / 16999764
trachea0 / 524130 
umbilical cord28 / 136802046
uterus83 / 232878356
vascular49 / 51780946
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200763_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12861.2
Adipocyte7162.4
AdrenalCortex6714.85
Adrenalgland5750.8
Amygdala2517.75
Appendix6513.2
AtrioventricularNode1788.7
BDCA4+_DentriticCells13960.75
Bonemarrow7898.35
BronchialEpithelialCells7788.4
CD105+_Endothelial11072.85
CD14+_Monocytes11600.55
CD19+_BCells(neg._sel.)15070.85
CD33+_Myeloid14002.2
CD34+15936.55
CD4+_Tcells17899.3
CD56+_NKCells12470.4
CD71+_EarlyErythroid7529.65
CD8+_Tcells13663.35
CardiacMyocytes7733.4
Caudatenucleus1748.6
Cerebellum1914.8
CerebellumPeduncles3058.55
CiliaryGanglion1601.2
CingulateCortex1485.75
Colorectaladenocarcinoma9973.25
DorsalRootGanglion2370.15
FetalThyroid6690.05
Fetalbrain5233.5
Fetalliver3533.7
Fetallung5757.75
GlobusPallidus787.7
Heart18943.75
Hypothalamus3230.4
Kidney3742.8
Leukemia_chronicMyelogenousK-5629644.05
Leukemia_promyelocytic-HL-605954.85
Leukemialymphoblastic(MOLT-4)7519.8
Liver11118.5
Lung14719.3
Lymphnode7811.35
Lymphoma_burkitts(Daudi)10435.4
Lymphoma_burkitts(Raji)14765.8
MedullaOblongata1820.05
OccipitalLobe1487.2
OlfactoryBulb4579.1
Ovary5003
Pancreas4370.1
PancreaticIslet5033.55
ParietalLobe1386.1
Pituitary4289.05
Placenta5337.5
Pons1291.2
PrefrontalCortex3943.75
Prostate17051.8
Salivarygland5991.55
SkeletalMuscle7377.5
Skin5715.8
SmoothMuscle9150.2
Spinalcord3211.45
SubthalamicNucleus1039.35
SuperiorCervicalGanglion1599.45
TemporalLobe2821.35
Testis5033.65
TestisGermCell4461.5
TestisIntersitial2749.75
TestisLeydigCell2560.1
TestisSeminiferousTubule3233.8
Thalamus1747.1
Thymus10038.25
Thyroid10757.65
Tongue7942.55
Tonsil7622.75
Trachea5202.15
TrigeminalGanglion2648.7
Uterus11373.4
UterusCorpus6822.1
WholeBlood9888
Wholebrain4672.65
colon7086.75
pineal_day5416.2
pineal_night5249.08
retina8693.2
small_intestine7447.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P37445
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala14.98 ± 0.24
Basal Forebrain15.05 ± 0.23
Basal Part of Pons14.55 ± 0.27
Cerebellar Cortex14.56 ± 0.14
Cerebellar Nuclei14.92 ± 0.3
Claustrum14.59 ± 0.28
Epithalamus14.73 ± 0.43
Frontal Lobe14.64 ± 0.29
Globus Pallidus15.73 ± 0.17
Hypothalamus14.95 ± 0.36
Insula14.79 ± 0.22
Limbic Lobe14.57 ± 0.34
Mesencephalon14.84 ± 0.41
Myelencephalon14.71 ± 0.36
Occipital Lobe14.5 ± 0.31
Parietal Lobe14.64 ± 0.29
Pontine Tegmentum14.79 ± 0.24
Striatum15.15 ± 0.33
Subthalamus14.85 ± 0.34
Temporal Lobe14.68 ± 0.29
Thalamus14.67 ± 0.25
White Matter15.43 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rplp1CBCerebellum16.75
21.33
Rplp1CTXCerebral cortex57.83
46.41
Rplp1HIPHippocampal region63.49
100
Rplp1HPFHippocampal formation60.77
79.11
Rplp1HYHypothalamus43.22
43.03
Rplp1LSXLateral septal complex35.21
28.27
Rplp1MBMidbrain42.17
44.36
Rplp1MYMedulla46.03
58.71
Rplp1OLFOlfactory bulb38.29
31.74
Rplp1PPons39.58
48.51
Rplp1PALPallidum42.05
45.34
Rplp1RHPRetrohippocampal region56.13
47.35
Rplp1sAMYStriatum-like amygdalar nuclei75.53
65.53
Rplp1STRStriatum29.74
24.01
Rplp1STRdStriatum dorsal region20.72
16.8
Rplp1STRvStriatum ventral region33.49
23.61
Rplp1THThalamus25.5
24.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000158 16 34 49 AAGVNVEPFWPGLFAK Peptide Atlas
RLA1_HUMAN_33 16 33 48 AAGVNVEPFWPGLFAK PRIDE
RLA1_HUMAN_98 17 98 114 KEESEESDDDMGFGLFD PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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