AutismKB 2.0

Annotation Detail for RPN2


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Basic Information Top
Gene Symbol:RPN2 ( RIBIIR,RPN-II,RPNII,SWP1 )
Gene Full Name: ribophorin II
Band: 20q11.23
Quick LinksEntrez ID:6185; OMIM: 180490; Uniprot ID:RPN2_HUMAN; ENSEMBL ID: ENSG00000118705; HGNC ID: 10382
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body17 / 70761240
blastocyst24 / 62319385
fetus73 / 564012129
neonate2 / 3109764
infant7 / 23620296
juvenile9 / 55556161
adult478 / 1939121246
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor10 / 12794781
bladder carcinoma11 / 17475629
breast (mammary gland) tumor31 / 94178329
cervical tumor22 / 34366640
chondrosarcoma29 / 82823350
colorectal tumor69 / 114246603
esophageal tumor12 / 17290694
gastrointestinal tumor44 / 119369368
germ cell tumor39 / 263845147
glioma10 / 10688393
head and neck tumor39 / 136302286
kidney tumor18 / 68959261
leukemia21 / 95842219
liver tumor25 / 96359259
lung tumor26 / 103127252
lymphoma20 / 71755278
non-neoplasia5 / 9725051
normal540 / 3360307160
ovarian tumor38 / 76682495
pancreatic tumor82 / 104616783
primitive neuroectodermal tumor of the CNS33 / 125680262
prostate cancer38 / 102680370
retinoblastoma9 / 46356194
skin tumor50 / 124949400
soft tissue/muscle tissue tumor36 / 125191287
uterine tumor32 / 90257354
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland10 / 33197301
ascites14 / 40015349
bladder4 / 29757134
blood29 / 123478234
bone20 / 71655279
bone marrow1 / 4880120
brain108 / 110098998
cervix25 / 48171518
connective tissue22 / 149255147
ear6 / 16212370
embryonic tissue64 / 215722296
esophagus12 / 20209593
eye51 / 211054241
heart9 / 89626100
intestine93 / 234472396
kidney33 / 211777155
larynx3 / 24145124
liver37 / 207743178
lung73 / 336974216
lymph8 / 44270180
lymph node22 / 91610240
mammary gland42 / 153271274
mouth8 / 67052119
muscle32 / 107715297
nerve7 / 15768443
ovary47 / 102051460
pancreas94 / 214812437
parathyroid3 / 20539146
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta124 / 280825441
prostate44 / 189345232
salivary gland0 / 201550 
skin72 / 210574341
spleen3 / 5395255
stomach25 / 96619258
testis115 / 330442348
thymus3 / 8113136
thyroid28 / 47473589
tonsil3 / 16999176
trachea0 / 524130 
umbilical cord2 / 13680146
uterus42 / 232878180
vascular11 / 51780212
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208689_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1224.1
Adipocyte535.75
AdrenalCortex143
Adrenalgland269.45
Amygdala58.85
Appendix97.3
AtrioventricularNode51.65
BDCA4+_DentriticCells1804.55
Bonemarrow307.15
BronchialEpithelialCells744.05
CD105+_Endothelial457.15
CD14+_Monocytes764.15
CD19+_BCells(neg._sel.)756
CD33+_Myeloid1082.25
CD34+1460.95
CD4+_Tcells563
CD56+_NKCells1042.7
CD71+_EarlyErythroid270.9
CD8+_Tcells472.35
CardiacMyocytes778.3
Caudatenucleus59
Cerebellum45.15
CerebellumPeduncles42.65
CiliaryGanglion25.45
CingulateCortex18.65
Colorectaladenocarcinoma716.55
DorsalRootGanglion89.1
FetalThyroid536.6
Fetalbrain149.65
Fetalliver304.8
Fetallung402.6
GlobusPallidus15.15
Heart30.55
Hypothalamus95.3
Kidney240.1
Leukemia_chronicMyelogenousK-562584.9
Leukemia_promyelocytic-HL-60302.1
Leukemialymphoblastic(MOLT-4)562.55
Liver185.65
Lung415.45
Lymphnode307.25
Lymphoma_burkitts(Daudi)524.55
Lymphoma_burkitts(Raji)438.85
MedullaOblongata36.65
OccipitalLobe60.15
OlfactoryBulb208.05
Ovary234.55
Pancreas334.65
PancreaticIslet402.9
ParietalLobe23.5
Pituitary319.7
Placenta1758.3
Pons31.55
PrefrontalCortex67.55
Prostate582
Salivarygland156.65
SkeletalMuscle30.45
Skin55.6
SmoothMuscle1555
Spinalcord97.3
SubthalamicNucleus12.4
SuperiorCervicalGanglion41.2
TemporalLobe18.85
Testis407.55
TestisGermCell444.85
TestisIntersitial262.45
TestisLeydigCell419
TestisSeminiferousTubule290.1
Thalamus51.15
Thymus299.85
Thyroid892.45
Tongue140.75
Tonsil314
Trachea388.55
TrigeminalGanglion57.5
Uterus117
UterusCorpus220.95
WholeBlood294.8
Wholebrain96.5
colon300.15
pineal_day894.56
pineal_night961.68
retina364.925
small_intestine384.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P108994
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.15 ± 0.24
Basal Forebrain7.86 ± 0.1
Basal Part of Pons7.74 ± 0.24
Cerebellar Cortex7.7 ± 0.2
Cerebellar Nuclei7.96 ± 0.25
Claustrum8.05 ± 0.36
Epithalamus8.11 ± 0.15
Frontal Lobe7.8 ± 0.26
Globus Pallidus8.2 ± 0.17
Hypothalamus8.05 ± 0.34
Insula7.81 ± 0.21
Limbic Lobe7.95 ± 0.36
Mesencephalon7.95 ± 0.27
Myelencephalon7.87 ± 0.24
Occipital Lobe7.92 ± 0.26
Parietal Lobe7.86 ± 0.31
Pontine Tegmentum7.96 ± 0.26
Striatum8.08 ± 0.27
Subthalamus7.74 ± 0.14
Temporal Lobe7.89 ± 0.24
Thalamus7.89 ± 0.2
White Matter8.3 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rpn2CBCerebellum29.62
52.92
Rpn2CTXCerebral cortex39.81
39.25
Rpn2HIPHippocampal region62.03
59.29
Rpn2HPFHippocampal formation56.67
55.78
Rpn2HYHypothalamus36.7
36.52
Rpn2LSXLateral septal complex51.69
50.89
Rpn2MBMidbrain19.38
20.97
Rpn2MYMedulla31.41
33.62
Rpn2OLFOlfactory bulb54.99
52.75
Rpn2PPons19.67
20.32
Rpn2PALPallidum29.66
29.72
Rpn2RHPRetrohippocampal region48.51
51.24
Rpn2sAMYStriatum-like amygdalar nuclei43.45
39.43
Rpn2STRStriatum29.94
27.33
Rpn2STRdStriatum dorsal region19.96
18.2
Rpn2STRvStriatum ventral region43.25
36.28
Rpn2THThalamus13.96
12.59
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000701 31 39 69 ASLDRPFTNLESAFYSIVGLSSLGAQVPDAK Peptide Atlas
RPN2_HUMAN_151 27 151 177 LSKEETVLATVQALQTASHLSQQADLR PRIDE
RPN2_HUMAN_155 24 155 178 EETVLATVQALQTASHLSQQADLR PRIDE
RPN2_HUMAN_178 12 178 189 SIVEEIEDLVAR PRIDE
RPN2_HUMAN_179 12 179 190 SIVEEIEDLVAR PRIDE
RPN2_HUMAN_23 14 23 36 LTPTHYLTKHDVER PRIDE
RPN2_HUMAN_244 22 244 265 NFESLSEAFSVASAAAVLSHNR PRIDE
RPN2_HUMAN_245 22 245 266 NFESLSEAFSVASAAAVLSHNR PRIDE
RPN2_HUMAN_266 23 266 288 YHVPVVVVPEGSASDTHEQAILR PRIDE
RPN2_HUMAN_322 18 322 339 TSFTPVGDVFELNFMNVK PRIDE
RPN2_HUMAN_323 18 323 340 TSFTPVGDVFELNFMNVK PRIDE
RPN2_HUMAN_442 14 442 455 TGQEVVFVAEPDNK PRIDE
RPN2_HUMAN_524 8 524 531 QEIQHLFR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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