AutismKB 2.0

Annotation Detail for RPS2


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Basic Information Top
Gene Symbol:RPS2 ( LLREP3,MGC102851,MGC117344,MGC117345 )
Gene Full Name: ribosomal protein S2
Band: 16p13.3
Quick LinksEntrez ID:6187; OMIM: 603624; Uniprot ID:RS2_HUMAN; ENSEMBL ID: ENSG00000140988; HGNC ID: 10404
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst10 / 62319160
fetus38 / 56401267
neonate7 / 31097225
infant1 / 2362042
juvenile1 / 5555617
adult231 / 1939121119
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult40 / 193912120
embryoid body122 / 707611724
blastocyst156 / 623192503
fetus197 / 564012349
neonate32 / 310971029
infant6 / 23620254
juvenile25 / 55556449
adult2005 / 19391211033
embryoid body89 / 707611257
blastocyst114 / 623191829
fetus60 / 564012106
neonate4 / 31097128
infant1 / 2362042
juvenile11 / 55556197
adult968 / 1939121499
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma7 / 17475400
breast (mammary gland) tumor43 / 94178456
cervical tumor15 / 34366436
chondrosarcoma21 / 82823253
colorectal tumor32 / 114246280
esophageal tumor5 / 17290289
gastrointestinal tumor49 / 119369410
germ cell tumor78 / 263845295
glioma32 / 106883299
head and neck tumor7 / 13630251
kidney tumor31 / 68959449
leukemia7 / 9584273
liver tumor14 / 96359145
lung tumor60 / 103127581
lymphoma28 / 71755390
non-neoplasia5 / 9725051
normal253 / 336030775
ovarian tumor20 / 76682260
pancreatic tumor44 / 104616420
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer18 / 102680175
retinoblastoma11 / 46356237
skin tumor52 / 124949416
soft tissue/muscle tissue tumor36 / 125191287
uterine tumor33 / 90257365
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal24 / 33603077
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer22 / 102680214
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
adrenal tumor18 / 127941406
bladder carcinoma9 / 17475515
breast (mammary gland) tumor138 / 941781465
cervical tumor102 / 343662968
chondrosarcoma165 / 828231992
colorectal tumor225 / 1142461969
esophageal tumor4 / 17290231
gastrointestinal tumor314 / 1193692630
germ cell tumor370 / 2638451402
glioma139 / 1068831300
head and neck tumor89 / 136302652
kidney tumor184 / 689592668
leukemia54 / 95842563
liver tumor92 / 96359954
lung tumor524 / 1031275081
lymphoma256 / 717553567
non-neoplasia48 / 97250493
normal2094 / 3360307623
ovarian tumor136 / 766821773
pancreatic tumor287 / 1046162743
primitive neuroectodermal tumor of the CNS207 / 1256801647
prostate cancer359 / 1026803496
retinoblastoma156 / 463563365
skin tumor244 / 1249491952
soft tissue/muscle tissue tumor362 / 1251912891
uterine tumor161 / 902571783
adrenal tumor25 / 127941954
bladder carcinoma4 / 17475228
breast (mammary gland) tumor165 / 941781752
cervical tumor129 / 343663753
chondrosarcoma57 / 82823688
colorectal tumor124 / 1142461085
esophageal tumor2 / 17290115
gastrointestinal tumor50 / 119369418
germ cell tumor441 / 2638451671
glioma150 / 1068831403
head and neck tumor66 / 136302484
kidney tumor125 / 689591812
leukemia18 / 95842187
liver tumor68 / 96359705
lung tumor595 / 1031275769
lymphoma239 / 717553330
non-neoplasia13 / 97250133
normal1419 / 3360307422
ovarian tumor126 / 766821643
pancreatic tumor236 / 1046162255
primitive neuroectodermal tumor of the CNS175 / 1256801392
prostate cancer135 / 1026801314
retinoblastoma224 / 463564832
skin tumor315 / 1249492521
soft tissue/muscle tissue tumor393 / 1251913139
uterine tumor66 / 90257731
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland7 / 33197210
ascites12 / 40015299
bladder3 / 29757100
blood5 / 12347840
bone9 / 71655125
bone marrow4 / 4880181
brain83 / 110098975
cervix15 / 48171311
connective tissue30 / 149255200
ear0 / 162120 
embryonic tissue33 / 215722152
esophagus5 / 20209247
eye34 / 211054161
heart1 / 8962611
intestine48 / 234472204
kidney48 / 211777226
larynx1 / 2414541
liver15 / 20774372
lung94 / 336974278
lymph12 / 44270271
lymph node31 / 91610338
mammary gland51 / 153271332
mouth1 / 6705214
muscle8 / 10771574
nerve1 / 1576863
ovary40 / 102051391
pancreas74 / 214812344
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta32 / 280825113
prostate39 / 189345205
salivary gland5 / 20155248
skin56 / 210574265
spleen2 / 5395237
stomach38 / 96619393
testis34 / 330442102
thymus0 / 811310 
thyroid0 / 474730 
tonsil9 / 16999529
trachea0 / 524130 
umbilical cord7 / 13680511
uterus48 / 232878206
vascular7 / 51780135
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow2 / 4880140
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine6 / 23447225
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary4 / 10205139
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate24 / 189345126
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular3 / 5178057
adipose tissue7 / 13106534
adrenal gland20 / 33197602
ascites109 / 400152723
bladder10 / 29757336
blood85 / 123478688
bone203 / 716552833
bone marrow85 / 488011741
brain415 / 1100989376
cervix103 / 481712138
connective tissue183 / 1492551226
ear11 / 16212678
embryonic tissue542 / 2157222512
esophagus4 / 20209197
eye299 / 2110541416
heart15 / 89626167
intestine296 / 2344721262
kidney228 / 2117771076
larynx8 / 24145331
liver137 / 207743659
lung615 / 3369741825
lymph207 / 442704675
lymph node168 / 916101833
mammary gland151 / 153271985
mouth7 / 67052104
muscle185 / 1077151717
nerve11 / 15768697
ovary203 / 1020511989
pancreas374 / 2148121741
parathyroid7 / 20539340
pharynx10 / 41328241
pituitary gland5 / 16585301
placenta229 / 280825815
prostate396 / 1893452091
salivary gland59 / 201552927
skin286 / 2105741358
spleen28 / 53952518
stomach232 / 966192401
testis77 / 330442233
thymus4 / 8113149
thyroid12 / 47473252
tonsil65 / 169993823
trachea0 / 524130 
umbilical cord32 / 136802339
uterus341 / 2328781464
vascular17 / 51780328
adipose tissue1 / 1310676
adrenal gland26 / 33197783
ascites14 / 40015349
bladder23 / 29757772
blood54 / 123478437
bone69 / 71655962
bone marrow105 / 488012151
brain353 / 1100989320
cervix129 / 481712677
connective tissue31 / 149255207
ear0 / 162120 
embryonic tissue401 / 2157221858
esophagus2 / 2020998
eye330 / 2110541563
heart5 / 8962655
intestine153 / 234472652
kidney127 / 211777599
larynx2 / 2414582
liver73 / 207743351
lung653 / 3369741937
lymph230 / 442705195
lymph node15 / 91610163
mammary gland168 / 1532711096
mouth0 / 670520 
muscle113 / 1077151049
nerve10 / 15768634
ovary200 / 1020511959
pancreas256 / 2148121191
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland2 / 16585120
placenta284 / 2808251011
prostate141 / 189345744
salivary gland63 / 201553125
skin337 / 2105741600
spleen14 / 53952259
stomach19 / 96619196
testis17 / 33044251
thymus5 / 8113161
thyroid3 / 4747363
tonsil131 / 169997706
trachea0 / 524130 
umbilical cord5 / 13680365
uterus347 / 2328781490
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 221798_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts8830.7
Adipocyte5064.15
AdrenalCortex5781.1
Adrenalgland4212.85
Amygdala3312.6
Appendix5060.85
AtrioventricularNode1645.1
BDCA4+_DentriticCells8255.5
Bonemarrow6107.85
BronchialEpithelialCells10452.75
CD105+_Endothelial8845.1
CD14+_Monocytes6330.4
CD19+_BCells(neg._sel.)7410.85
CD33+_Myeloid8485.85
CD34+11091.25
CD4+_Tcells6828.5
CD56+_NKCells7228.25
CD71+_EarlyErythroid4261.7
CD8+_Tcells6874.15
CardiacMyocytes8651.8
Caudatenucleus3238.4
Cerebellum1707.3
CerebellumPeduncles2420.45
CiliaryGanglion1475.15
CingulateCortex1185.4
Colorectaladenocarcinoma6358
DorsalRootGanglion2393.65
FetalThyroid8203.55
Fetalbrain9502.05
Fetalliver4441.3
Fetallung6115.75
GlobusPallidus915.15
Heart8305.65
Hypothalamus2877
Kidney2957.1
Leukemia_chronicMyelogenousK-5628969.85
Leukemia_promyelocytic-HL-6010018.1
Leukemialymphoblastic(MOLT-4)8091.95
Liver8034.55
Lung9741.35
Lymphnode6675.15
Lymphoma_burkitts(Daudi)14708.6
Lymphoma_burkitts(Raji)17612.4
MedullaOblongata1787.05
OccipitalLobe1934.35
OlfactoryBulb2589.85
Ovary5330.85
Pancreas5397.65
PancreaticIslet8085.4
ParietalLobe1601.9
Pituitary4890.8
Placenta4408.05
Pons1223.6
PrefrontalCortex2809
Prostate9582.3
Salivarygland3957.35
SkeletalMuscle5209.8
Skin3943.6
SmoothMuscle10263.1
Spinalcord3935.7
SubthalamicNucleus1549.4
SuperiorCervicalGanglion1613.85
TemporalLobe1986.9
Testis4796.1
TestisGermCell3956.5
TestisIntersitial2640.9
TestisLeydigCell3289.35
TestisSeminiferousTubule3661.35
Thalamus2426.05
Thymus6838
Thyroid6487.9
Tongue6354.4
Tonsil6760
Trachea4193.1
TrigeminalGanglion2726.05
Uterus5261.35
UterusCorpus4024
WholeBlood5994.4
Wholebrain3784.85
colon8120.5
pineal_day4704.08
pineal_night3757.14
retina4636.425
small_intestine7706.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P14544
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.93 ± 0.46
Basal Forebrain7.37 ± 0.16
Basal Part of Pons6.99 ± 0.44
Cerebellar Cortex6.97 ± 0.51
Cerebellar Nuclei6.62 ± 0.43
Claustrum6.48 ± 0.84
Epithalamus7.1 ± 0.4
Frontal Lobe6.94 ± 0.54
Globus Pallidus7.41 ± 0.38
Hypothalamus7.06 ± 0.6
Insula7.03 ± 0.46
Limbic Lobe6.74 ± 0.49
Mesencephalon6.78 ± 0.58
Myelencephalon6.9 ± 0.52
Occipital Lobe6.34 ± 0.47
Parietal Lobe6.78 ± 0.47
Pontine Tegmentum6.88 ± 0.55
Striatum7.06 ± 0.39
Subthalamus6.87 ± 0.43
Temporal Lobe7.04 ± 0.46
Thalamus6.75 ± 0.56
White Matter7.4 ± 0.49
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000324 17 126 142 AFVAIGDYNGHVGLGVK Peptide Atlas
RS2_HUMAN_174 10 174 183 IGKPHTVPCK PRIDE
RS2_HUMAN_2 21 2 22 ADDAGAAGGPGGPGGPGMGNR PRIDE
RS2_HUMAN_200 11 200 210 GTGIVSAPVPK PRIDE
RS2_HUMAN_211 16 211 226 KLLMMAGIDDCYTSAR PRIDE
RS2_HUMAN_227 11 227 237 GCTATLGNFAK PRIDE
RS2_HUMAN_228 11 228 238 GCTATLGNFAK PRIDE
RS2_HUMAN_246 11 246 256 TYSYLTPDLWK PRIDE
RS2_HUMAN_263 12 263 274 SPYQEFTDHLVK PRIDE
RS2_HUMAN_55 11 55 65 AEDKEWMPVTK PRIDE
RS2_HUMAN_76 13 76 88 SLEEIYLFSLPIK PRIDE
RS2_HUMAN_77 13 77 89 SLEEIYLFSLPIK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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