AutismKB 2.0

Annotation Detail for RPS15


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Basic Information Top
Gene Symbol:RPS15 ( MGC111130,RIG )
Gene Full Name: ribosomal protein S15
Band: 19p13.3
Quick LinksEntrez ID:6209; OMIM: 180535; Uniprot ID:RS15_HUMAN; ENSEMBL ID: ENSG00000115268; HGNC ID: 10388
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst30 / 62319481
fetus60 / 564012106
neonate29 / 31097932
infant6 / 23620254
juvenile5 / 5555689
adult662 / 1939121341
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor8 / 12794625
bladder carcinoma0 / 174750 
breast (mammary gland) tumor46 / 94178488
cervical tumor8 / 34366232
chondrosarcoma20 / 82823241
colorectal tumor38 / 114246332
esophageal tumor1 / 1729057
gastrointestinal tumor35 / 119369293
germ cell tumor53 / 263845200
glioma27 / 106883252
head and neck tumor8 / 13630258
kidney tumor27 / 68959391
leukemia55 / 95842573
liver tumor37 / 96359383
lung tumor41 / 103127397
lymphoma31 / 71755432
non-neoplasia13 / 97250133
normal732 / 3360307217
ovarian tumor23 / 76682299
pancreatic tumor146 / 1046161395
primitive neuroectodermal tumor of the CNS39 / 125680310
prostate cancer119 / 1026801158
retinoblastoma14 / 46356302
skin tumor59 / 124949472
soft tissue/muscle tissue tumor32 / 125191255
uterine tumor17 / 90257188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland12 / 33197361
ascites23 / 40015574
bladder4 / 29757134
blood56 / 123478453
bone27 / 71655376
bone marrow33 / 48801676
brain190 / 1100989172
cervix8 / 48171166
connective tissue15 / 149255100
ear6 / 16212370
embryonic tissue102 / 215722472
esophagus1 / 2020949
eye64 / 211054303
heart15 / 89626167
intestine66 / 234472281
kidney40 / 211777188
larynx2 / 2414582
liver50 / 207743240
lung56 / 336974166
lymph21 / 44270474
lymph node10 / 91610109
mammary gland54 / 153271352
mouth0 / 670520 
muscle76 / 107715705
nerve1 / 1576863
ovary39 / 102051382
pancreas162 / 214812754
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland13 / 16585783
placenta38 / 280825135
prostate141 / 189345744
salivary gland4 / 20155198
skin66 / 210574313
spleen12 / 53952222
stomach14 / 96619144
testis27 / 33044281
thymus2 / 8113124
thyroid5 / 47473105
tonsil15 / 16999882
trachea0 / 524130 
umbilical cord25 / 136801827
uterus46 / 232878197
vascular11 / 51780212
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200819_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts12570.55
Adipocyte5514.05
AdrenalCortex5470.5
Adrenalgland5243.05
Amygdala5567.45
Appendix5817.25
AtrioventricularNode1597.9
BDCA4+_DentriticCells12275.9
Bonemarrow4850.25
BronchialEpithelialCells7066.6
CD105+_Endothelial10158.3
CD14+_Monocytes10507
CD19+_BCells(neg._sel.)15784.65
CD33+_Myeloid10459.85
CD34+14304.45
CD4+_Tcells13041.2
CD56+_NKCells11517.2
CD71+_EarlyErythroid5807.1
CD8+_Tcells11607.15
CardiacMyocytes5622.5
Caudatenucleus4075.1
Cerebellum5168.2
CerebellumPeduncles8975.5
CiliaryGanglion1446.95
CingulateCortex3922.05
Colorectaladenocarcinoma9880
DorsalRootGanglion2164.9
FetalThyroid6919.75
Fetalbrain5547.7
Fetalliver2931.3
Fetallung5757.9
GlobusPallidus2275.1
Heart12604.65
Hypothalamus6107.55
Kidney4363.45
Leukemia_chronicMyelogenousK-5628407.35
Leukemia_promyelocytic-HL-607636.4
Leukemialymphoblastic(MOLT-4)7622
Liver11052.55
Lung16664.25
Lymphnode7291.7
Lymphoma_burkitts(Daudi)14086.15
Lymphoma_burkitts(Raji)22990.3
MedullaOblongata3938.2
OccipitalLobe3481.7
OlfactoryBulb4815.2
Ovary4900.25
Pancreas5004.25
PancreaticIslet7273.05
ParietalLobe3752.8
Pituitary7189.35
Placenta5064.65
Pons3119.7
PrefrontalCortex7414.8
Prostate19613.1
Salivarygland5094.7
SkeletalMuscle4099.7
Skin4812.3
SmoothMuscle7146.4
Spinalcord5187.8
SubthalamicNucleus3522.6
SuperiorCervicalGanglion1364.5
TemporalLobe4905.4
Testis5775.85
TestisGermCell4814.15
TestisIntersitial3099.5
TestisLeydigCell2810.75
TestisSeminiferousTubule3412.65
Thalamus4548.75
Thymus8135.3
Thyroid13636.85
Tongue6357.65
Tonsil6861.8
Trachea4067.3
TrigeminalGanglion2508.05
Uterus6969.7
UterusCorpus4965.25
WholeBlood7669.1
Wholebrain7123.1
colon7433
pineal_day7613.72
pineal_night7206
retina7188.05
small_intestine6437.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P272590
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.37 ± 0.23
Basal Forebrain13.52 ± 0.19
Basal Part of Pons13.42 ± 0.49
Cerebellar Cortex13.3 ± 0.58
Cerebellar Nuclei13.36 ± 0.42
Claustrum13.05 ± 0.45
Epithalamus13.38 ± 0.25
Frontal Lobe13.24 ± 0.34
Globus Pallidus13.91 ± 0.32
Hypothalamus13.45 ± 0.25
Insula13.29 ± 0.33
Limbic Lobe13.05 ± 0.37
Mesencephalon13.25 ± 0.45
Myelencephalon13.24 ± 0.39
Occipital Lobe12.87 ± 0.37
Parietal Lobe13.21 ± 0.31
Pontine Tegmentum13.25 ± 0.33
Striatum13.36 ± 0.29
Subthalamus13.33 ± 0.1
Temporal Lobe13.29 ± 0.33
Thalamus13.19 ± 0.29
White Matter13.92 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rps15CBCerebellum16.37
21.95
Rps15CTXCerebral cortex92.89
86.24
Rps15HIPHippocampal region95.98
100
Rps15HPFHippocampal formation98.46
100
Rps15HYHypothalamus98.45
86.93
Rps15LSXLateral septal complex100
84.04
Rps15MBMidbrain56.22
54.8
Rps15MYMedulla45.38
51.65
Rps15OLFOlfactory bulb76.4
69.66
Rps15PPons54.17
58.37
Rps15PALPallidum86.71
79.81
Rps15RHPRetrohippocampal region81.29
83.2
Rps15sAMYStriatum-like amygdalar nuclei100
88.09
Rps15STRStriatum70
57.38
Rps15STRdStriatum dorsal region58.11
45.13
Rps15STRvStriatum ventral region69.18
54.09
Rps15THThalamus73.08
65.76
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001744 19 82 100 DMIILPEMVGSMVGVYNGK Peptide Atlas
RS15_HUMAN_1 9 1 9 AEVEQKKKR PRIDE
RS15_HUMAN_100 27 100 126 TFNQVEIKPEMIGHYLGEFSITYKPVK PRIDE
RS15_HUMAN_127 13 127 139 HGRPGIGATHSSR PRIDE
RS15_HUMAN_130 10 130 139 PGIGATHSSR PRIDE
RS15_HUMAN_18 22 18 39 GVDLDQLLDMSYEQLMQLYSAR PRIDE
RS15_HUMAN_2 9 2 10 AEVEQKKKR PRIDE
RS15_HUMAN_33 7 33 39 MQLYSAR PRIDE
RS15_HUMAN_51 8 51 58 KQHSLLKR PRIDE
RS15_HUMAN_64 13 64 76 KEAPPMEKPEVVK PRIDE
RS15_HUMAN_65 12 65 76 EAPPMEKPEVVK PRIDE
RS15_HUMAN_81 19 81 99 DMIILPEMVGSMVGVYNGK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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