AutismKB 2.0

Annotation Detail for RTN1


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Basic Information Top
Gene Symbol:RTN1 ( MGC133250,NSP )
Gene Full Name: reticulon 1
Band: 14q23.1
Quick LinksEntrez ID:6252; OMIM: 600865; Uniprot ID:RTN1_HUMAN; ENSEMBL ID: ENSG00000139970; HGNC ID: 10467
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus230 / 564012407
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult115 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma15 / 106883140
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal494 / 3360307147
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain572 / 1100989519
cervix0 / 481710 
connective tissue1 / 1492556
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye23 / 211054108
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung31 / 33697491
lymph0 / 442700 
lymph node1 / 9161010
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve3 / 15768190
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203485_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.35
Adipocyte7.2
AdrenalCortex9.3
Adrenalgland6.75
Amygdala8617.3
Appendix11.2
AtrioventricularNode7.4
BDCA4+_DentriticCells49.2
Bonemarrow7.95
BronchialEpithelialCells6.9
CD105+_Endothelial7.5
CD14+_Monocytes233.5
CD19+_BCells(neg._sel.)7.7
CD33+_Myeloid237.95
CD34+9.4
CD4+_Tcells7.6
CD56+_NKCells8.55
CD71+_EarlyErythroid7.05
CD8+_Tcells6.7
CardiacMyocytes11.3
Caudatenucleus1359.2
Cerebellum2862.2
CerebellumPeduncles2019.35
CiliaryGanglion33.95
CingulateCortex2841.45
Colorectaladenocarcinoma7.05
DorsalRootGanglion135.9
FetalThyroid7.2
Fetalbrain6974.9
Fetalliver6.45
Fetallung5.75
GlobusPallidus2042.4
Heart11.3
Hypothalamus3022.25
Kidney6.6
Leukemia_chronicMyelogenousK-5626.35
Leukemia_promyelocytic-HL-606.25
Leukemialymphoblastic(MOLT-4)5.7
Liver11.35
Lung9.05
Lymphnode6.15
Lymphoma_burkitts(Daudi)10.2
Lymphoma_burkitts(Raji)11.35
MedullaOblongata2107.25
OccipitalLobe4148.15
OlfactoryBulb11.05
Ovary5.5
Pancreas6.35
PancreaticIslet53.35
ParietalLobe2810.35
Pituitary363.4
Placenta7.45
Pons1146.55
PrefrontalCortex4327.4
Prostate43.8
Salivarygland6.1
SkeletalMuscle10.95
Skin6.45
SmoothMuscle8.4
Spinalcord844.65
SubthalamicNucleus2771.4
SuperiorCervicalGanglion43.9
TemporalLobe1904.85
Testis6.25
TestisGermCell5.85
TestisIntersitial6.45
TestisLeydigCell7.75
TestisSeminiferousTubule6.3
Thalamus1075.3
Thymus5.5
Thyroid8.8
Tongue8.25
Tonsil7.15
Trachea14
TrigeminalGanglion77.35
Uterus6
UterusCorpus7.6
WholeBlood33.9
Wholebrain4641.4
colon7.95
pineal_day50.06
pineal_night56.88
retina329.35
small_intestine17.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P140290
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.88 ± 0.31
Basal Forebrain9.37 ± 0.54
Basal Part of Pons10.3 ± 0.27
Cerebellar Cortex10.08 ± 0.32
Cerebellar Nuclei9.14 ± 0.57
Claustrum10.35 ± 0.37
Epithalamus9.71 ± 0.53
Frontal Lobe10.05 ± 0.49
Globus Pallidus7.91 ± 0.73
Hypothalamus10.47 ± 0.31
Insula10.09 ± 0.29
Limbic Lobe9.91 ± 0.7
Mesencephalon9.58 ± 0.59
Myelencephalon9.64 ± 0.77
Occipital Lobe9.13 ± 0.78
Parietal Lobe9.76 ± 0.51
Pontine Tegmentum9.69 ± 0.7
Striatum8.52 ± 0.65
Subthalamus9.64 ± 0.66
Temporal Lobe10.07 ± 0.47
Thalamus9.38 ± 0.46
White Matter8.03 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rtn1CBCerebellum100
100
Rtn1CTXCerebral cortex100
100
Rtn1HIPHippocampal region100
100
Rtn1HPFHippocampal formation100
100
Rtn1HYHypothalamus100
100
Rtn1LSXLateral septal complex100
100
Rtn1MBMidbrain100
100
Rtn1MYMedulla95.53
100
Rtn1OLFOlfactory bulb100
100
Rtn1PPons99.22
100
Rtn1PALPallidum100
100
Rtn1RHPRetrohippocampal region100
100
Rtn1sAMYStriatum-like amygdalar nuclei100
100
Rtn1STRStriatum100
100
Rtn1STRdStriatum dorsal region100
100
Rtn1STRvStriatum ventral region100
100
Rtn1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00517379 16 553 568 KPEEDSSSNQSPAATK Peptide Atlas
RTN1_HUMAN_500 10 500 509 EETGVRAEER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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