AutismKB 2.0

Annotation Detail for RXRB


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Basic Information Top
Gene Symbol:RXRB ( DAUDI6,H-2RIIBP,MGC1831,NR2B2,RCoR-1 )
Gene Full Name: retinoid X receptor, beta
Band: 6p21.32
Quick LinksEntrez ID:6257; OMIM: 180246; Uniprot ID:RXRB_HUMAN; ENSEMBL ID: ENSG00000204231; HGNC ID: 10478
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus27 / 56401247
neonate2 / 3109764
infant4 / 23620169
juvenile3 / 5555653
adult122 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor3 / 3436687
chondrosarcoma3 / 8282336
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor10 / 26384537
glioma11 / 106883102
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor4 / 9635941
lung tumor11 / 103127106
lymphoma7 / 7175597
non-neoplasia4 / 9725041
normal160 / 336030747
ovarian tumor5 / 7668265
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer13 / 102680126
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites1 / 4001524
bladder0 / 297570 
blood10 / 12347880
bone1 / 7165513
bone marrow1 / 4880120
brain61 / 110098955
cervix5 / 48171103
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye9 / 21105442
heart8 / 8962689
intestine12 / 23447251
kidney11 / 21177751
larynx1 / 2414541
liver11 / 20774352
lung15 / 33697444
lymph4 / 4427090
lymph node2 / 9161021
mammary gland6 / 15327139
mouth4 / 6705259
muscle1 / 1077159
nerve0 / 157680 
ovary6 / 10205158
pancreas15 / 21481269
parathyroid5 / 20539243
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate16 / 18934584
salivary gland0 / 201550 
skin13 / 21057461
spleen4 / 5395274
stomach5 / 9661951
testis15 / 33044245
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus15 / 23287864
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209148_at
Cell line Expression level Expression bar
721_B_lymphoblasts79.45
Adipocyte52.8
AdrenalCortex55.3
Adrenalgland45.4
Amygdala53.3
Appendix65.15
AtrioventricularNode45.25
BDCA4+_DentriticCells124.65
Bonemarrow52.1
BronchialEpithelialCells46.45
CD105+_Endothelial56.6
CD14+_Monocytes68
CD19+_BCells(neg._sel.)90.9
CD33+_Myeloid122.95
CD34+73.15
CD4+_Tcells129.65
CD56+_NKCells181.2
CD71+_EarlyErythroid48.65
CD8+_Tcells173.75
CardiacMyocytes56.4
Caudatenucleus47.15
Cerebellum65.8
CerebellumPeduncles114.3
CiliaryGanglion42.85
CingulateCortex64.65
Colorectaladenocarcinoma44.7
DorsalRootGanglion40.65
FetalThyroid58.5
Fetalbrain56.4
Fetalliver19.7
Fetallung44.3
GlobusPallidus38.6
Heart97.4
Hypothalamus66.8
Kidney42.7
Leukemia_chronicMyelogenousK-56247.2
Leukemia_promyelocytic-HL-6047.05
Leukemialymphoblastic(MOLT-4)51.35
Liver80.1
Lung72.8
Lymphnode51.1
Lymphoma_burkitts(Daudi)57.6
Lymphoma_burkitts(Raji)73.5
MedullaOblongata58.6
OccipitalLobe47.95
OlfactoryBulb41.7
Ovary33
Pancreas42.55
PancreaticIslet49.7
ParietalLobe55.4
Pituitary55.85
Placenta56.4
Pons52.1
PrefrontalCortex137
Prostate80.3
Salivarygland31.55
SkeletalMuscle56.95
Skin40.35
SmoothMuscle53
Spinalcord56.85
SubthalamicNucleus51.8
SuperiorCervicalGanglion66.2
TemporalLobe92.05
Testis41.15
TestisGermCell44.7
TestisIntersitial46.75
TestisLeydigCell47.6
TestisSeminiferousTubule46.6
Thalamus53.85
Thymus43.35
Thyroid75
Tongue51.55
Tonsil51.95
Trachea40.15
TrigeminalGanglion52.8
Uterus43.85
UterusCorpus50.05
WholeBlood58.85
Wholebrain72.5
colon48.4
pineal_day85.86
pineal_night76.5
retina74.175
small_intestine32.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12992_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4 ± 0.8
Basal Forebrain3.87 ± 0.55
Basal Part of Pons4.24 ± 0.53
Cerebellar Cortex4.28 ± 0.48
Cerebellar Nuclei3.95 ± 0.6
Claustrum3.76 ± 0.83
Epithalamus4.05 ± 0.59
Frontal Lobe4.05 ± 0.53
Globus Pallidus3.6 ± 0.47
Hypothalamus3.97 ± 0.45
Insula3.91 ± 0.49
Limbic Lobe4.06 ± 0.57
Mesencephalon4.07 ± 0.73
Myelencephalon3.99 ± 0.57
Occipital Lobe4.16 ± 0.5
Parietal Lobe4.01 ± 0.45
Pontine Tegmentum3.88 ± 0.46
Striatum3.82 ± 0.5
Subthalamus4.02 ± 0.26
Temporal Lobe4.02 ± 0.57
Thalamus3.94 ± 0.55
White Matter4.3 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RxrbCBCerebellum14.07
11
RxrbCTXCerebral cortex11.94
7.22
RxrbHIPHippocampal region21.83
11.65
RxrbHPFHippocampal formation18.37
10.53
RxrbHYHypothalamus7.24
4.68
RxrbLSXLateral septal complex3.67
2.25
RxrbMBMidbrain3.87
2.73
RxrbMYMedulla7.19
5.32
RxrbOLFOlfactory bulb14.77
9.21
RxrbPPons6.66
4.99
RxrbPALPallidum3.83
2.37
RxrbRHPRetrohippocampal region13.63
9.36
RxrbsAMYStriatum-like amygdalar nuclei8.27
5.15
RxrbSTRStriatum7.42
4.05
RxrbSTRdStriatum dorsal region7.38
4.02
RxrbSTRvStriatum ventral region8.97
4.23
RxrbTHThalamus14.36
8.68
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010238 15 188 202 GLHCPPPPGGPGAGK Peptide Atlas
RXRB_HUMAN_281 22 281 302 GKDKDGDGEGAGGAPEEMPVDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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