AutismKB 2.0

Annotation Detail for S100A8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:S100A8 ( 60B8AG,CAGA,CFAG,CGLA,CP-10,L1Ag,MA387,MIF,MRP8,NIF,P8 )
Gene Full Name: S100 calcium binding protein A8
Band: 1q21.3
Quick LinksEntrez ID:6279; OMIM: 123885; Uniprot ID:S10A8_HUMAN; ENSEMBL ID: ENSG00000143546; HGNC ID: 10498
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult218 / 1939121112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor5 / 17290289
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor120 / 136302880
kidney tumor0 / 689590 
leukemia60 / 95842626
liver tumor4 / 9635941
lung tumor12 / 103127116
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal219 / 336030765
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood67 / 123478542
bone1 / 7165513
bone marrow62 / 488011270
brain4 / 11009893
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus5 / 20209247
eye5 / 21105423
heart6 / 8962666
intestine2 / 2344728
kidney2 / 2117779
larynx12 / 24145496
liver4 / 20774319
lung22 / 33697465
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth92 / 670521372
muscle17 / 107715157
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx72 / 413281742
pituitary gland0 / 165850 
placenta8 / 28082528
prostate2 / 18934510
salivary gland0 / 201550 
skin7 / 21057433
spleen5 / 5395292
stomach4 / 9661941
testis4 / 33044212
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202917_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.4
Adipocyte4.45
AdrenalCortex8
Adrenalgland9.9
Amygdala4.9
Appendix20.3
AtrioventricularNode46.55
BDCA4+_DentriticCells4216
Bonemarrow17415.1
BronchialEpithelialCells3895.1
CD105+_Endothelial1776.1
CD14+_Monocytes16938
CD19+_BCells(neg._sel.)160.15
CD33+_Myeloid24674.9
CD34+691.9
CD4+_Tcells7.7
CD56+_NKCells58.05
CD71+_EarlyErythroid809.3
CD8+_Tcells4.25
CardiacMyocytes6
Caudatenucleus4.15
Cerebellum3.7
CerebellumPeduncles5.35
CiliaryGanglion19.35
CingulateCortex5
Colorectaladenocarcinoma4.55
DorsalRootGanglion10.5
FetalThyroid50.8
Fetalbrain16.5
Fetalliver89.25
Fetallung5169.1
GlobusPallidus3.3
Heart15.6
Hypothalamus8.65
Kidney3.95
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-604.05
Leukemialymphoblastic(MOLT-4)3.6
Liver6.35
Lung689.7
Lymphnode237.3
Lymphoma_burkitts(Daudi)5.85
Lymphoma_burkitts(Raji)6.8
MedullaOblongata4.3
OccipitalLobe4.1
OlfactoryBulb3.6
Ovary957.5
Pancreas149.3
PancreaticIslet1368.3
ParietalLobe4.75
Pituitary6.8
Placenta819.95
Pons5.6
PrefrontalCortex6.5
Prostate45.3
Salivarygland9.05
SkeletalMuscle100.3
Skin90.5
SmoothMuscle5.2
Spinalcord129.9
SubthalamicNucleus5.3
SuperiorCervicalGanglion5.9
TemporalLobe70.9
Testis6.5
TestisGermCell7.3
TestisIntersitial7.75
TestisLeydigCell9.15
TestisSeminiferousTubule6.6
Thalamus8.45
Thymus510.15
Thyroid22.05
Tongue27093.1
Tonsil14410.45
Trachea402.55
TrigeminalGanglion51.2
Uterus5.8
UterusCorpus5.1
WholeBlood23660.35
Wholebrain3.7
colon4.65
pineal_day6.04
pineal_night5.52
retina328.975
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P434809
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.63 ± 1.06
Basal Forebrain2.78 ± 0.44
Basal Part of Pons2.94 ± 0.83
Cerebellar Cortex2.21 ± 0.75
Cerebellar Nuclei2.59 ± 0.7
Claustrum2.61 ± 0.76
Epithalamus2.63 ± 0.6
Frontal Lobe2.46 ± 0.79
Globus Pallidus3.41 ± 1.05
Hypothalamus2.73 ± 0.64
Insula2.72 ± 0.78
Limbic Lobe2.54 ± 0.91
Mesencephalon2.89 ± 0.83
Myelencephalon2.67 ± 0.75
Occipital Lobe2.8 ± 0.93
Parietal Lobe2.6 ± 0.73
Pontine Tegmentum2.68 ± 0.99
Striatum3.18 ± 0.68
Subthalamus2.24 ± 0.85
Temporal Lobe2.62 ± 0.73
Thalamus2.5 ± 0.65
White Matter2.43 ± 0.33
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00004450 12 36 47 KLLETECPQYIR Peptide Atlas
S10A8_HUMAN_0 0 0 0 ALNSIIDVYHK PRIDE
S10A8_HUMAN_0 0 0 0 GNFHAVYR PRIDE
S10A8_HUMAN_0 0 0 0 KLLETECPQYIR PRIDE
S10A8_HUMAN_0 0 0 0 KLLETECPQYIRK PRIDE
S10A8_HUMAN_0 0 0 0 LLETECPQYIR PRIDE
S10A8_HUMAN_0 0 0 0 MLTELEK PRIDE
S10A8_HUMAN_0 0 0 0 MLTELEKALNSIIDVYHK PRIDE
S10A8_HUMAN_0 0 0 0 MLTELEKALNSIIDVYHKYSLIK PRIDE
S10A8_HUMAN_23 12 23 34 GNFHAVYRDDLK PRIDE
S10A8_HUMAN_23 13 23 35 GNFHAVYRDDLKK PRIDE
S10A8_HUMAN_23 8 23 30 GNFHAVYR PRIDE
S10A8_HUMAN_35 12 35 46 KLLETECPQYIR PRIDE
S10A8_HUMAN_35 13 35 47 KLLETECPQYIRK PRIDE
S10A8_HUMAN_36 11 36 46 LLETECPQYIR PRIDE
S10A8_HUMAN_36 12 36 47 LLETECPQYIRK PRIDE
S10A8_HUMAN_37 11 37 47 LLETECPQYIR PRIDE
S10A8_HUMAN_47 9 47 55 KKGADVWFK PRIDE
S10A8_HUMAN_48 8 48 55 KGADVWFK PRIDE
S10A8_HUMAN_7 11 7 17 ALNSIIDVYHK PRIDE
S10A8_HUMAN_7 16 7 22 ALNSIIDVYHKYSLIK PRIDE
S10A8_HUMAN_7 24 7 30 ALNSIIDVYHKYSLIKGNFHAVYR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved