AutismKB 2.0

Annotation Detail for ACSM3


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Basic Information Top
Gene Symbol:ACSM3 ( SA,SAH )
Gene Full Name: acyl-CoA synthetase medium-chain family member 3
Band: 16p12.3
Quick LinksEntrez ID:6296; OMIM: 145505; Uniprot ID:ACSM3_HUMAN; ENSEMBL ID: ENSG00000005187; HGNC ID: 10522
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor4 / 6895958
leukemia22 / 95842229
liver tumor6 / 9635962
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal74 / 336030722
ovarian tumor5 / 7668265
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer9 / 10268087
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood4 / 12347832
bone4 / 7165555
bone marrow21 / 48801430
brain10 / 11009899
cervix2 / 4817141
connective tissue9 / 14925560
ear1 / 1621261
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine19 / 23447281
kidney40 / 211777188
larynx0 / 241450 
liver10 / 20774348
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary6 / 10205158
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate9 / 18934547
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach4 / 9661941
testis9 / 33044227
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210377_at
Cell line Expression level Expression bar
721_B_lymphoblasts32.8
Adipocyte4.75
AdrenalCortex5.2
Adrenalgland4.3
Amygdala4.9
Appendix5
AtrioventricularNode4.15
BDCA4+_DentriticCells5.25
Bonemarrow4.8
BronchialEpithelialCells4.65
CD105+_Endothelial4.85
CD14+_Monocytes5.1
CD19+_BCells(neg._sel.)5
CD33+_Myeloid6
CD34+8.45
CD4+_Tcells5.2
CD56+_NKCells5.6
CD71+_EarlyErythroid4.5
CD8+_Tcells4.65
CardiacMyocytes6.55
Caudatenucleus4.3
Cerebellum3.85
CerebellumPeduncles5.7
CiliaryGanglion3.7
CingulateCortex5
Colorectaladenocarcinoma4.75
DorsalRootGanglion4.25
FetalThyroid4.6
Fetalbrain4.7
Fetalliver5.2
Fetallung4
GlobusPallidus3.55
Heart6.85
Hypothalamus5.2
Kidney4.65
Leukemia_chronicMyelogenousK-562305.3
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.8
Liver6.4
Lung5.2
Lymphnode4.05
Lymphoma_burkitts(Daudi)6.2
Lymphoma_burkitts(Raji)6.75
MedullaOblongata4.4
OccipitalLobe4.3
OlfactoryBulb3.8
Ovary15.7
Pancreas4.6
PancreaticIslet5.7
ParietalLobe5.1
Pituitary5.6
Placenta4.85
Pons5.8
PrefrontalCortex5.85
Prostate5.6
Salivarygland3.85
SkeletalMuscle6.4
Skin4.15
SmoothMuscle5.4
Spinalcord5.1
SubthalamicNucleus4.45
SuperiorCervicalGanglion6.7
TemporalLobe4.45
Testis4.1
TestisGermCell4.05
TestisIntersitial4.3
TestisLeydigCell6.25
TestisSeminiferousTubule4.1
Thalamus5
Thymus3.65
Thyroid5.85
Tongue4.85
Tonsil4.7
Trachea3.95
TrigeminalGanglion5
Uterus3.8
UterusCorpus4.8
WholeBlood5.25
Wholebrain3.85
colon4.8
pineal_day5.96
pineal_night5.76
retina5.75
small_intestine4.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P934800
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.89 ± 0.65
Basal Forebrain3.72 ± 0.42
Basal Part of Pons3.43 ± 0.46
Cerebellar Cortex3.64 ± 0.54
Cerebellar Nuclei3.84 ± 0.52
Claustrum3.38 ± 0.66
Epithalamus4.5 ± 0.55
Frontal Lobe3.84 ± 0.49
Globus Pallidus4.41 ± 0.46
Hypothalamus3.93 ± 0.55
Insula3.88 ± 0.41
Limbic Lobe3.67 ± 0.43
Mesencephalon3.89 ± 0.57
Myelencephalon3.82 ± 0.53
Occipital Lobe3.62 ± 0.61
Parietal Lobe3.61 ± 0.6
Pontine Tegmentum3.83 ± 0.56
Striatum4.05 ± 0.52
Subthalamus4.2 ± 0.48
Temporal Lobe3.77 ± 0.58
Thalamus3.82 ± 0.53
White Matter5.13 ± 0.13
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Acsm3CBCerebellum19.01
29.99
Acsm3CTXCerebral cortex59.2
55.85
Acsm3HIPHippocampal region25.71
44.46
Acsm3HPFHippocampal formation26.98
40.67
Acsm3HYHypothalamus13.84
14.23
Acsm3LSXLateral septal complex6.17
8.86
Acsm3MBMidbrain16.94
18.92
Acsm3MYMedulla21.27
30.61
Acsm3OLFOlfactory bulb34.67
31.99
Acsm3PPons16.93
25.16
Acsm3PALPallidum8.26
7.24
Acsm3RHPRetrohippocampal region30.47
35.88
Acsm3sAMYStriatum-like amygdalar nuclei20.26
19.69
Acsm3STRStriatum14.1
13.18
Acsm3STRdStriatum dorsal region7.85
7.58
Acsm3STRvStriatum ventral region30.66
23.72
Acsm3THThalamus14.76
15.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00072008 12 77 88 KPSNPAFWWINR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018