AutismKB 2.0

Annotation Detail for SLC22A23


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Basic Information Top
Gene Symbol:SLC22A23 ( C6orf85,DKFZp434F011,FLJ22174 )
Gene Full Name: solute carrier family 22, member 23
Band: 6p25.2
Quick LinksEntrez ID:63027; OMIM: 611697; Uniprot ID:S22AN_HUMAN; ENSEMBL ID: ENSG00000137266; HGNC ID: 21106
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus52 / 56401292
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor20 / 26384575
glioma5 / 10688346
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal165 / 336030749
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder2 / 2975767
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain62 / 110098956
cervix5 / 48171103
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye5 / 21105423
heart4 / 8962644
intestine19 / 23447281
kidney9 / 21177742
larynx0 / 241450 
liver8 / 20774338
lung21 / 33697462
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth1 / 6705214
muscle4 / 10771537
nerve1 / 1576863
ovary1 / 1020519
pancreas7 / 21481232
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta15 / 28082553
prostate6 / 18934531
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach3 / 9661931
testis9 / 33044227
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P7882
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.14 ± 0.23
Basal Forebrain9.43 ± 0.26
Basal Part of Pons9.54 ± 0.25
Cerebellar Cortex9.03 ± 0.15
Cerebellar Nuclei10.25 ± 0.33
Claustrum8.96 ± 0.3
Epithalamus8.8 ± 0.62
Frontal Lobe9.38 ± 0.38
Globus Pallidus10.05 ± 0.24
Hypothalamus9.01 ± 0.35
Insula9.26 ± 0.23
Limbic Lobe9.17 ± 0.24
Mesencephalon9.54 ± 0.49
Myelencephalon9.45 ± 0.47
Occipital Lobe9.66 ± 0.36
Parietal Lobe9.48 ± 0.33
Pontine Tegmentum9.49 ± 0.42
Striatum10.14 ± 0.3
Subthalamus9.81 ± 0.45
Temporal Lobe9.32 ± 0.29
Thalamus9.76 ± 0.29
White Matter11.08 ± 0.19
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
3110004L20RikCBCerebellum13.75
17.08
3110004L20RikCTXCerebral cortex13.7
11.18
3110004L20RikHIPHippocampal region8.38
10.13
3110004L20RikHPFHippocampal formation9.9
10.77
3110004L20RikHYHypothalamus4.94
4.53
3110004L20RikLSXLateral septal complex6.93
6.65
3110004L20RikMBMidbrain11.3
13.25
3110004L20RikMYMedulla16.52
23.87
3110004L20RikOLFOlfactory bulb14.95
14.74
3110004L20RikPPons17.35
22.55
3110004L20RikPALPallidum16.51
19.57
3110004L20RikRHPRetrohippocampal region11.45
10.86
3110004L20RiksAMYStriatum-like amygdalar nuclei5.6
5.28
3110004L20RikSTRStriatum10.62
8.29
3110004L20RikSTRdStriatum dorsal region12.36
9.59
3110004L20RikSTRvStriatum ventral region9.37
6.58
3110004L20RikTHThalamus8.66
8.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018