AutismKB 2.0

Annotation Detail for SC4MOL


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Basic Information Top
Gene Symbol:SC4MOL ( DESP4,ERG25,MGC104344 )
Gene Full Name: sterol-C4-methyl oxidase-like
Band: 4q32-q34
Quick LinksEntrez ID:6307; OMIM: 607545; Uniprot ID:ERG25_HUMAN; ENSEMBL ID: ENSG00000052802; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst7 / 62319112
fetus45 / 56401279
neonate4 / 31097128
infant5 / 23620211
juvenile11 / 55556197
adult115 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor10 / 11936983
germ cell tumor22 / 26384583
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor14 / 68959203
leukemia8 / 9584283
liver tumor12 / 96359124
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal273 / 336030781
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer2 / 10268019
retinoblastoma6 / 46356129
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland8 / 33197240
ascites2 / 4001549
bladder4 / 29757134
blood10 / 12347880
bone5 / 7165569
bone marrow4 / 4880181
brain103 / 110098993
cervix3 / 4817162
connective tissue7 / 14925546
ear2 / 16212123
embryonic tissue20 / 21572292
esophagus1 / 2020949
eye13 / 21105461
heart2 / 8962622
intestine14 / 23447259
kidney21 / 21177799
larynx2 / 2414582
liver30 / 207743144
lung14 / 33697441
lymph0 / 442700 
lymph node1 / 9161010
mammary gland8 / 15327152
mouth1 / 6705214
muscle1 / 1077159
nerve4 / 15768253
ovary8 / 10205178
pancreas13 / 21481260
parathyroid5 / 20539243
pharynx9 / 41328217
pituitary gland0 / 165850 
placenta20 / 28082571
prostate12 / 18934563
salivary gland7 / 20155347
skin18 / 21057485
spleen1 / 5395218
stomach5 / 9661951
testis24 / 33044272
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209146_at
Cell line Expression level Expression bar
721_B_lymphoblasts669.45
Adipocyte664
AdrenalCortex493.6
Adrenalgland708.7
Amygdala218
Appendix17.2
AtrioventricularNode14.8
BDCA4+_DentriticCells38.5
Bonemarrow14.95
BronchialEpithelialCells1855.85
CD105+_Endothelial18.4
CD14+_Monocytes11.6
CD19+_BCells(neg._sel.)40.25
CD33+_Myeloid19.85
CD34+17.5
CD4+_Tcells19.6
CD56+_NKCells42.1
CD71+_EarlyErythroid11.45
CD8+_Tcells18.4
CardiacMyocytes29.95
Caudatenucleus38
Cerebellum17.35
CerebellumPeduncles23.75
CiliaryGanglion15.25
CingulateCortex51.4
Colorectaladenocarcinoma88.55
DorsalRootGanglion22.05
FetalThyroid17.95
Fetalbrain277.25
Fetalliver907.8
Fetallung333.7
GlobusPallidus34.2
Heart22.8
Hypothalamus319.35
Kidney28.7
Leukemia_chronicMyelogenousK-562217.7
Leukemia_promyelocytic-HL-60114.15
Leukemialymphoblastic(MOLT-4)174.4
Liver46.75
Lung115.25
Lymphnode13.05
Lymphoma_burkitts(Daudi)99.3
Lymphoma_burkitts(Raji)91.8
MedullaOblongata29.6
OccipitalLobe169.75
OlfactoryBulb197.4
Ovary9.95
Pancreas93.65
PancreaticIslet46.25
ParietalLobe63.6
Pituitary18.15
Placenta27.65
Pons23.25
PrefrontalCortex338.35
Prostate514.8
Salivarygland13.1
SkeletalMuscle21.85
Skin20.25
SmoothMuscle50.1
Spinalcord407.35
SubthalamicNucleus51.55
SuperiorCervicalGanglion19.85
TemporalLobe42.35
Testis78.9
TestisGermCell216.1
TestisIntersitial45.15
TestisLeydigCell44.4
TestisSeminiferousTubule28.9
Thalamus92.85
Thymus11.9
Thyroid31.7
Tongue30.05
Tonsil19.9
Trachea29.3
TrigeminalGanglion22.5
Uterus17.35
UterusCorpus14.6
WholeBlood20.15
Wholebrain145.9
colon177.2
pineal_day166.42
pineal_night193.94
retina237.9
small_intestine197.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P110184
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.47 ± 0.62
Basal Forebrain4.32 ± 0.4
Basal Part of Pons4.74 ± 0.42
Cerebellar Cortex4.33 ± 0.49
Cerebellar Nuclei4.46 ± 0.61
Claustrum5.27 ± 0.44
Epithalamus4.45 ± 0.58
Frontal Lobe4.93 ± 0.46
Globus Pallidus3.67 ± 0.7
Hypothalamus5.03 ± 0.74
Insula4.93 ± 0.3
Limbic Lobe4.58 ± 0.57
Mesencephalon4.77 ± 0.63
Myelencephalon4.68 ± 0.65
Occipital Lobe4.24 ± 0.6
Parietal Lobe4.58 ± 0.58
Pontine Tegmentum4.71 ± 0.57
Striatum4.05 ± 0.93
Subthalamus5.05 ± 0.6
Temporal Lobe4.84 ± 0.48
Thalamus4.7 ± 0.6
White Matter5.18 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sc4molCBCerebellum18.61
21.59
Sc4molCTXCerebral cortex50.06
43.47
Sc4molHIPHippocampal region28.63
37.01
Sc4molHPFHippocampal formation34.74
38.96
Sc4molHYHypothalamus34.09
32.55
Sc4molLSXLateral septal complex9.58
8.15
Sc4molMBMidbrain34.12
36.68
Sc4molMYMedulla53.81
65.14
Sc4molOLFOlfactory bulb41.59
35.16
Sc4molPPons43.34
50.51
Sc4molPALPallidum22.49
27.41
Sc4molRHPRetrohippocampal region44.27
41.32
Sc4molsAMYStriatum-like amygdalar nuclei32.2
28.92
Sc4molSTRStriatum25.1
21.55
Sc4molSTRdStriatum dorsal region29.13
25.49
Sc4molSTRvStriatum ventral region16.22
12.37
Sc4molTHThalamus27.81
28.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00502606 14 271 284 IFGTDSQYNAYNEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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