AutismKB 2.0

Annotation Detail for SCD


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Basic Information Top
Gene Symbol:SCD ( FADS5,MSTP008,SCD1,SCDOS )
Gene Full Name: stearoyl-CoA desaturase (delta-9-desaturase)
Band: 10q24.31
Quick LinksEntrez ID:6319; OMIM: 604031; Uniprot ID:ACOD_HUMAN; ENSEMBL ID: ENSG00000099194; HGNC ID: 10571
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body32 / 70761452
blastocyst25 / 62319401
fetus155 / 564012274
neonate6 / 31097192
infant8 / 23620338
juvenile52 / 55556935
adult684 / 1939121352
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor7 / 12794547
bladder carcinoma1 / 1747557
breast (mammary gland) tumor192 / 941782038
cervical tumor25 / 34366727
chondrosarcoma27 / 82823325
colorectal tumor54 / 114246472
esophageal tumor3 / 17290173
gastrointestinal tumor61 / 119369511
germ cell tumor181 / 263845686
glioma40 / 106883374
head and neck tumor37 / 136302271
kidney tumor36 / 68959522
leukemia11 / 95842114
liver tumor129 / 963591338
lung tumor28 / 103127271
lymphoma34 / 71755473
non-neoplasia21 / 97250215
normal1375 / 3360307409
ovarian tumor41 / 76682534
pancreatic tumor74 / 104616707
primitive neuroectodermal tumor of the CNS46 / 125680366
prostate cancer68 / 102680662
retinoblastoma19 / 46356409
skin tumor61 / 124949488
soft tissue/muscle tissue tumor33 / 125191263
uterine tumor30 / 90257332
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue102 / 131067782
adrenal gland12 / 33197361
ascites14 / 40015349
bladder14 / 29757470
blood27 / 123478218
bone30 / 71655418
bone marrow2 / 4880140
brain873 / 1100989792
cervix27 / 48171560
connective tissue20 / 149255133
ear5 / 16212308
embryonic tissue99 / 215722458
esophagus3 / 20209148
eye69 / 211054326
heart26 / 89626290
intestine108 / 234472460
kidney56 / 211777264
larynx9 / 24145372
liver153 / 207743736
lung85 / 336974252
lymph34 / 44270768
lymph node5 / 9161054
mammary gland220 / 1532711435
mouth25 / 67052372
muscle55 / 107715510
nerve5 / 15768317
ovary71 / 102051695
pancreas76 / 214812353
parathyroid9 / 20539438
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta45 / 280825160
prostate85 / 189345448
salivary gland4 / 20155198
skin94 / 210574446
spleen2 / 5395237
stomach23 / 96619238
testis109 / 330442329
thymus20 / 81131246
thyroid2 / 4747342
tonsil0 / 169990 
trachea19 / 52413362
umbilical cord2 / 13680146
uterus38 / 232878163
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200832_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1256.5
Adipocyte10797.55
AdrenalCortex331.55
Adrenalgland710.95
Amygdala1984
Appendix17.45
AtrioventricularNode74.85
BDCA4+_DentriticCells33.3
Bonemarrow41.45
BronchialEpithelialCells2507.4
CD105+_Endothelial50.65
CD14+_Monocytes7.55
CD19+_BCells(neg._sel.)14.85
CD33+_Myeloid9.9
CD34+46.8
CD4+_Tcells10.05
CD56+_NKCells28.7
CD71+_EarlyErythroid5.45
CD8+_Tcells10.05
CardiacMyocytes107.4
Caudatenucleus1429.55
Cerebellum847.55
CerebellumPeduncles1431.05
CiliaryGanglion324.3
CingulateCortex1483.75
Colorectaladenocarcinoma368.3
DorsalRootGanglion266.4
FetalThyroid29.4
Fetalbrain518.7
Fetalliver1638.3
Fetallung546.2
GlobusPallidus570.9
Heart25.85
Hypothalamus3937.7
Kidney26.6
Leukemia_chronicMyelogenousK-562636.05
Leukemia_promyelocytic-HL-60353.15
Leukemialymphoblastic(MOLT-4)731.15
Liver459
Lung276.6
Lymphnode66.4
Lymphoma_burkitts(Daudi)378.6
Lymphoma_burkitts(Raji)616.25
MedullaOblongata1578.55
OccipitalLobe1896.55
OlfactoryBulb804.25
Ovary35.65
Pancreas514.55
PancreaticIslet351.65
ParietalLobe2078.45
Pituitary42
Placenta21.7
Pons1013.05
PrefrontalCortex2062.55
Prostate439.8
Salivarygland19.85
SkeletalMuscle9.75
Skin35.65
SmoothMuscle526.1
Spinalcord3636.1
SubthalamicNucleus800.5
SuperiorCervicalGanglion105.5
TemporalLobe422.65
Testis153.35
TestisGermCell283.55
TestisIntersitial106
TestisLeydigCell85.45
TestisSeminiferousTubule142.25
Thalamus2201.15
Thymus145.7
Thyroid16.8
Tongue70.9
Tonsil48.3
Trachea56.55
TrigeminalGanglion81.7
Uterus22
UterusCorpus58.55
WholeBlood13.05
Wholebrain783.9
colon260.5
pineal_day316.12
pineal_night208.18
retina2019.275
small_intestine181.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P626920
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.27 ± 0.48
Basal Forebrain7.71 ± 0.47
Basal Part of Pons6.8 ± 0.54
Cerebellar Cortex6.63 ± 0.41
Cerebellar Nuclei7.43 ± 0.86
Claustrum7.77 ± 0.51
Epithalamus7.24 ± 0.69
Frontal Lobe7.08 ± 0.71
Globus Pallidus8.65 ± 0.37
Hypothalamus7.04 ± 1.27
Insula6.73 ± 0.33
Limbic Lobe6.86 ± 0.76
Mesencephalon7.33 ± 0.63
Myelencephalon7.21 ± 0.59
Occipital Lobe7.08 ± 0.65
Parietal Lobe7 ± 0.7
Pontine Tegmentum7.3 ± 0.45
Striatum7.13 ± 0.69
Subthalamus6.91 ± 0.36
Temporal Lobe6.87 ± 0.59
Thalamus7.46 ± 0.42
White Matter9.6 ± 0.55
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scd2CBCerebellum86.58
100
Scd2CTXCerebral cortex100
100
Scd2HIPHippocampal region100
100
Scd2HPFHippocampal formation100
100
Scd2HYHypothalamus100
100
Scd2LSXLateral septal complex100
100
Scd2MBMidbrain100
100
Scd2MYMedulla100
100
Scd2OLFOlfactory bulb100
100
Scd2PPons100
100
Scd2PALPallidum100
100
Scd2RHPRetrohippocampal region100
100
Scd2sAMYStriatum-like amygdalar nuclei100
100
Scd2STRStriatum100
100
Scd2STRdStriatum dorsal region100
100
Scd2STRvStriatum ventral region100
100
Scd2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ACOD_HUMAN_2 25 2 26 PAHLLQDDISSSYTTTTTITAPPSR PRIDE
PAp00004847 26 35 60 LETMPLYLEDDIRPDIKDDIYDPTYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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