AutismKB 2.0

Annotation Detail for SCP2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SCP2 ( DKFZp686C12188,DKFZp686D11188,NLTP,NSL-TP,SCP-2,SCP-CHI,SCP-X,SCPX )
Gene Full Name: sterol carrier protein 2
Band: 1p32.3
Quick LinksEntrez ID:6342; OMIM: 184755; Uniprot ID:NLTP_HUMAN; ENSEMBL ID: ENSG00000116171; HGNC ID: 10606
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus43 / 56401276
neonate3 / 3109796
infant0 / 236200 
juvenile3 / 5555653
adult221 / 1939121113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma65 / 174753719
breast (mammary gland) tumor14 / 94178148
cervical tumor0 / 343660 
chondrosarcoma13 / 82823156
colorectal tumor7 / 11424661
esophageal tumor3 / 17290173
gastrointestinal tumor5 / 11936941
germ cell tumor67 / 263845253
glioma43 / 106883402
head and neck tumor7 / 13630251
kidney tumor25 / 68959362
leukemia44 / 95842459
liver tumor33 / 96359342
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia9 / 9725092
normal537 / 3360307159
ovarian tumor1 / 7668213
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer28 / 102680272
retinoblastoma2 / 4635643
skin tumor22 / 124949176
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland8 / 33197240
ascites2 / 4001549
bladder69 / 297572318
blood7 / 12347856
bone8 / 71655111
bone marrow48 / 48801983
brain225 / 1100989204
cervix2 / 4817141
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue16 / 21572274
esophagus3 / 20209148
eye15 / 21105471
heart15 / 89626167
intestine26 / 234472110
kidney85 / 211777401
larynx1 / 2414541
liver89 / 207743428
lung33 / 33697497
lymph2 / 4427045
lymph node6 / 9161065
mammary gland19 / 153271123
mouth5 / 6705274
muscle18 / 107715167
nerve4 / 15768253
ovary5 / 10205148
pancreas33 / 214812153
parathyroid2 / 2053997
pharynx10 / 41328241
pituitary gland7 / 16585422
placenta22 / 28082578
prostate48 / 189345253
salivary gland18 / 20155893
skin39 / 210574185
spleen1 / 5395218
stomach7 / 9661972
testis91 / 330442275
thymus7 / 8113186
thyroid4 / 4747384
tonsil0 / 169990 
trachea14 / 52413267
umbilical cord0 / 136800 
uterus26 / 232878111
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201339_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts166.95
Adipocyte235.85
AdrenalCortex26.6
Adrenalgland25.4
Amygdala59.2
Appendix32.45
AtrioventricularNode23.15
BDCA4+_DentriticCells292.15
Bonemarrow28.15
BronchialEpithelialCells138.4
CD105+_Endothelial60.75
CD14+_Monocytes322.45
CD19+_BCells(neg._sel.)215.25
CD33+_Myeloid281.95
CD34+124.45
CD4+_Tcells133.1
CD56+_NKCells431.35
CD71+_EarlyErythroid24
CD8+_Tcells142.55
CardiacMyocytes96
Caudatenucleus25.1
Cerebellum11.75
CerebellumPeduncles15.65
CiliaryGanglion27.5
CingulateCortex29.4
Colorectaladenocarcinoma22.35
DorsalRootGanglion23.65
FetalThyroid107.65
Fetalbrain32.45
Fetalliver164.7
Fetallung59.4
GlobusPallidus14.1
Heart20.5
Hypothalamus64.85
Kidney36.65
Leukemia_chronicMyelogenousK-56264.35
Leukemia_promyelocytic-HL-6032.7
Leukemialymphoblastic(MOLT-4)96.3
Liver66.45
Lung13.9
Lymphnode51.75
Lymphoma_burkitts(Daudi)37.7
Lymphoma_burkitts(Raji)21.45
MedullaOblongata21.95
OccipitalLobe38.45
OlfactoryBulb58.1
Ovary30.85
Pancreas51.95
PancreaticIslet124.9
ParietalLobe23.6
Pituitary108.9
Placenta27.7
Pons15.1
PrefrontalCortex65.3
Prostate108.6
Salivarygland79.5
SkeletalMuscle23.4
Skin31.05
SmoothMuscle245.3
Spinalcord73
SubthalamicNucleus24.9
SuperiorCervicalGanglion20.7
TemporalLobe21.2
Testis12.65
TestisGermCell121.85
TestisIntersitial37.05
TestisLeydigCell29
TestisSeminiferousTubule29.7
Thalamus46
Thymus12.45
Thyroid150.2
Tongue39.5
Tonsil69.55
Trachea84.15
TrigeminalGanglion22.05
Uterus75.35
UterusCorpus14.2
WholeBlood164.65
Wholebrain22.25
colon442.95
pineal_day278.7
pineal_night251.58
retina92.075
small_intestine453.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P156922
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.18 ± 0.49
Basal Forebrain5.33 ± 0.3
Basal Part of Pons4.91 ± 0.56
Cerebellar Cortex5.09 ± 0.46
Cerebellar Nuclei4.79 ± 0.45
Claustrum4.75 ± 0.65
Epithalamus5.48 ± 0.43
Frontal Lobe5.09 ± 0.46
Globus Pallidus5.73 ± 0.26
Hypothalamus5.41 ± 0.44
Insula4.96 ± 0.39
Limbic Lobe4.92 ± 0.43
Mesencephalon5.25 ± 0.51
Myelencephalon5.04 ± 0.49
Occipital Lobe5.07 ± 0.41
Parietal Lobe5.22 ± 0.49
Pontine Tegmentum5.08 ± 0.51
Striatum5.01 ± 0.47
Subthalamus5.2 ± 0.56
Temporal Lobe5.04 ± 0.43
Thalamus5.24 ± 0.44
White Matter5.03 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scp2CBCerebellum0.46
0.95
Scp2CTXCerebral cortex1.47
1.67
Scp2HIPHippocampal region2.55
3.13
Scp2HPFHippocampal formation2.14
2.69
Scp2HYHypothalamus0.58
1.33
Scp2LSXLateral septal complex0.22
0.42
Scp2MBMidbrain0.72
1.18
Scp2MYMedulla1.11
1.51
Scp2OLFOlfactory bulb8.28
10.35
Scp2PPons3.44
6.99
Scp2PALPallidum0.47
1.09
Scp2RHPRetrohippocampal region0.74
1.18
Scp2sAMYStriatum-like amygdalar nuclei1.41
1.61
Scp2STRStriatum1.01
1.28
Scp2STRdStriatum dorsal region0.13
0.26
Scp2STRvStriatum ventral region4.6
5
Scp2THThalamus0.43
0.41
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NLTP_HUMAN_0 0 0 0 LQNLQLQPGNAK PRIDE
NLTP_HUMAN_0 0 0 0 LQNLQLQPGNAKL PRIDE
NLTP_HUMAN_151 18 151 168 YGLSAHPVAPQMFGYAGK PRIDE
NLTP_HUMAN_432 10 432 441 ANLVFKEIEK PRIDE
NLTP_HUMAN_442 11 442 452 KLEEEGEQFVK PRIDE
NLTP_HUMAN_443 10 443 452 LEEEGEQFVK PRIDE
NLTP_HUMAN_453 9 453 461 KIGGIFAFK PRIDE
NLTP_HUMAN_454 8 454 461 IGGIFAFK PRIDE
NLTP_HUMAN_470 9 470 478 EATWVVDVK PRIDE
NLTP_HUMAN_491 20 491 510 KADCTITMADSDFLALMTGK PRIDE
NLTP_HUMAN_511 11 511 521 MNPQSAFFQGK PRIDE
NLTP_HUMAN_512 11 512 522 MNPQSAFFQGK PRIDE
NLTP_HUMAN_525 10 525 534 ITGNMGLAMK PRIDE
NLTP_HUMAN_534 12 534 545 LQNLQLQPGNAK PRIDE
NLTP_HUMAN_534 13 534 546 LQNLQLQPGNAKL PRIDE
PAp00391800 12 298 309 WVINPSGGLISK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved