AutismKB 2.0

Annotation Detail for CCL25


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Basic Information Top
Gene Symbol:CCL25 ( Ckb15,MGC150327,SCYA25,TECK )
Gene Full Name: chemokine (C-C motif) ligand 25
Band: 19p13.2
Quick LinksEntrez ID:6370; OMIM: 602565; Uniprot ID:CCL25_HUMAN; ENSEMBL ID: ENSG00000131142; HGNC ID: 10624
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult5 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal10 / 33603072
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206988_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.3
Adipocyte5.4
AdrenalCortex5.7
Adrenalgland4.6
Amygdala5.6
Appendix5.75
AtrioventricularNode5.9
BDCA4+_DentriticCells5.6
Bonemarrow5.35
BronchialEpithelialCells5.25
CD105+_Endothelial5.3
CD14+_Monocytes5.6
CD19+_BCells(neg._sel.)5.65
CD33+_Myeloid6.75
CD34+6.8
CD4+_Tcells5.6
CD56+_NKCells6.25
CD71+_EarlyErythroid4.95
CD8+_Tcells5.15
CardiacMyocytes6.85
Caudatenucleus4.9
Cerebellum4.85
CerebellumPeduncles6.1
CiliaryGanglion4.05
CingulateCortex5.55
Colorectaladenocarcinoma5.3
DorsalRootGanglion4.1
FetalThyroid5.7
Fetalbrain5.45
Fetalliver4.7
Fetallung4.35
GlobusPallidus3.9
Heart6.85
Hypothalamus5.85
Kidney5.7
Leukemia_chronicMyelogenousK-5624.9
Leukemia_promyelocytic-HL-605.05
Leukemialymphoblastic(MOLT-4)4.4
Liver7.05
Lung5.85
Lymphnode4.75
Lymphoma_burkitts(Daudi)6.9
Lymphoma_burkitts(Raji)8.65
MedullaOblongata5.35
OccipitalLobe4.85
OlfactoryBulb4.3
Ovary3.65
Pancreas4.25
PancreaticIslet5.7
ParietalLobe5.7
Pituitary6.35
Placenta5.5
Pons6.9
PrefrontalCortex6.85
Prostate6.35
Salivarygland4.35
SkeletalMuscle6.35
Skin4.25
SmoothMuscle5.95
Spinalcord5.8
SubthalamicNucleus4.95
SuperiorCervicalGanglion6.6
TemporalLobe4.95
Testis4.75
TestisGermCell4.3
TestisIntersitial4.55
TestisLeydigCell5.35
TestisSeminiferousTubule5.1
Thalamus5.45
Thymus1053.8
Thyroid6.5
Tongue5.3
Tonsil5.25
Trachea5.25
TrigeminalGanglion8.7
Uterus4.4
UterusCorpus16.05
WholeBlood5.9
Wholebrain4.55
colon5.45
pineal_day6.56
pineal_night6.42
retina6.5
small_intestine657.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13207_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.19 ± 0.87
Basal Forebrain5.02 ± 0.75
Basal Part of Pons4.92 ± 0.63
Cerebellar Cortex4.91 ± 0.65
Cerebellar Nuclei4.87 ± 0.5
Claustrum5.13 ± 0.91
Epithalamus4.47 ± 0.56
Frontal Lobe5.06 ± 0.64
Globus Pallidus5.68 ± 0.74
Hypothalamus4.71 ± 0.84
Insula4.97 ± 0.74
Limbic Lobe5.26 ± 0.73
Mesencephalon5.02 ± 0.74
Myelencephalon5.13 ± 0.72
Occipital Lobe5.35 ± 0.71
Parietal Lobe5.06 ± 0.61
Pontine Tegmentum5.06 ± 0.71
Striatum5.36 ± 0.67
Subthalamus4.69 ± 0.92
Temporal Lobe4.99 ± 0.77
Thalamus5.15 ± 0.58
White Matter5.23 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccl25CBCerebellum1.73
3.49
Ccl25CTXCerebral cortex0.6
0.87
Ccl25HIPHippocampal region0.74
0.96
Ccl25HPFHippocampal formation0.53
0.76
Ccl25HYHypothalamus0.03
0.14
Ccl25LSXLateral septal complex0
0
Ccl25MBMidbrain0.35
0.7
Ccl25MYMedulla0.41
0.62
Ccl25OLFOlfactory bulb1.63
3.25
Ccl25PPons0.18
0.37
Ccl25PALPallidum0.16
0.28
Ccl25RHPRetrohippocampal region0.1
0.4
Ccl25sAMYStriatum-like amygdalar nuclei0.43
0.36
Ccl25STRStriatum0.27
0.3
Ccl25STRdStriatum dorsal region0.34
0.41
Ccl25STRvStriatum ventral region0.08
0.08
Ccl25THThalamus0.26
0.34
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018