AutismKB 2.0

Annotation Detail for SDC4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SDC4 ( MGC22217,SYND4 )
Gene Full Name: syndecan 4
Band: 20q13.12
Quick LinksEntrez ID:6385; OMIM: 600017; Uniprot ID:SDC4_HUMAN; ENSEMBL ID: ENSG00000124145; HGNC ID: 10661
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst2 / 6231932
fetus28 / 56401249
neonate5 / 31097160
infant0 / 236200 
juvenile1 / 5555617
adult123 / 193912163
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor7 / 11424661
esophageal tumor8 / 17290462
gastrointestinal tumor8 / 11936967
germ cell tumor12 / 26384545
glioma1 / 1068839
head and neck tumor11 / 13630280
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor12 / 96359124
lung tumor8 / 10312777
lymphoma1 / 7175513
non-neoplasia5 / 9725051
normal191 / 336030756
ovarian tumor6 / 7668278
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites6 / 40015149
bladder8 / 29757268
blood0 / 1234780 
bone7 / 7165597
bone marrow2 / 4880140
brain34 / 110098930
cervix6 / 48171124
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus8 / 20209395
eye7 / 21105433
heart6 / 8962666
intestine17 / 23447272
kidney19 / 21177789
larynx0 / 241450 
liver16 / 20774377
lung31 / 33697491
lymph0 / 442700 
lymph node1 / 9161010
mammary gland8 / 15327152
mouth6 / 6705289
muscle5 / 10771546
nerve0 / 157680 
ovary7 / 10205168
pancreas12 / 21481255
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta12 / 28082542
prostate14 / 18934573
salivary gland0 / 201550 
skin16 / 21057475
spleen1 / 5395218
stomach6 / 9661962
testis8 / 33044224
thymus1 / 8113112
thyroid6 / 47473126
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus11 / 23287847
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202071_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.1
Adipocyte192
AdrenalCortex692.5
Adrenalgland249.2
Amygdala117.3
Appendix30.3
AtrioventricularNode21.7
BDCA4+_DentriticCells9.7
Bonemarrow13.8
BronchialEpithelialCells1671
CD105+_Endothelial59.3
CD14+_Monocytes11.1
CD19+_BCells(neg._sel.)9.75
CD33+_Myeloid13.85
CD34+12
CD4+_Tcells15.9
CD56+_NKCells13.1
CD71+_EarlyErythroid18.05
CD8+_Tcells10.75
CardiacMyocytes101.65
Caudatenucleus159.7
Cerebellum68.15
CerebellumPeduncles68.65
CiliaryGanglion36.8
CingulateCortex276.65
Colorectaladenocarcinoma1266.3
DorsalRootGanglion15.15
FetalThyroid240.75
Fetalbrain9.6
Fetalliver78.05
Fetallung864.75
GlobusPallidus29.8
Heart267.2
Hypothalamus322.35
Kidney659.95
Leukemia_chronicMyelogenousK-56211.6
Leukemia_promyelocytic-HL-608.75
Leukemialymphoblastic(MOLT-4)7.35
Liver1482.2
Lung1480.4
Lymphnode16.95
Lymphoma_burkitts(Daudi)13.85
Lymphoma_burkitts(Raji)14.3
MedullaOblongata62.3
OccipitalLobe121.95
OlfactoryBulb139.35
Ovary27.45
Pancreas509.15
PancreaticIslet659.65
ParietalLobe97.45
Pituitary109.8
Placenta381.15
Pons84.9
PrefrontalCortex269.3
Prostate464.9
Salivarygland66.3
SkeletalMuscle28.95
Skin286.35
SmoothMuscle664.4
Spinalcord243.35
SubthalamicNucleus59.9
SuperiorCervicalGanglion16.8
TemporalLobe51.6
Testis260.7
TestisGermCell670.85
TestisIntersitial59.9
TestisLeydigCell96.4
TestisSeminiferousTubule343.75
Thalamus106.35
Thymus16.95
Thyroid318.2
Tongue130.85
Tonsil170.65
Trachea457.05
TrigeminalGanglion19.7
Uterus215.2
UterusCorpus35.9
WholeBlood14.1
Wholebrain287.6
colon346.35
pineal_day1003.48
pineal_night828.48
retina474.375
small_intestine140.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P373976
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.08 ± 0.63
Basal Forebrain4.11 ± 0.47
Basal Part of Pons3.49 ± 0.45
Cerebellar Cortex3.52 ± 0.55
Cerebellar Nuclei4.49 ± 0.68
Claustrum4.09 ± 0.74
Epithalamus3.85 ± 0.51
Frontal Lobe3.93 ± 0.76
Globus Pallidus5.65 ± 0.52
Hypothalamus3.73 ± 0.79
Insula3.73 ± 0.75
Limbic Lobe3.82 ± 0.7
Mesencephalon4.33 ± 0.69
Myelencephalon4.19 ± 0.73
Occipital Lobe4.4 ± 0.65
Parietal Lobe4.11 ± 0.7
Pontine Tegmentum4.35 ± 0.71
Striatum4.64 ± 0.81
Subthalamus4.43 ± 0.67
Temporal Lobe3.98 ± 0.71
Thalamus4.61 ± 0.53
White Matter4.5 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sdc4CBCerebellum11.02
24.77
Sdc4CTXCerebral cortex1.3
1.91
Sdc4HIPHippocampal region3.99
6.17
Sdc4HPFHippocampal formation4.24
6.11
Sdc4HYHypothalamus12.84
15.29
Sdc4LSXLateral septal complex1.05
1.13
Sdc4MBMidbrain2.17
4.04
Sdc4MYMedulla4.05
7.26
Sdc4OLFOlfactory bulb8.98
7.79
Sdc4PPons8.28
12.61
Sdc4PALPallidum1.89
1.66
Sdc4RHPRetrohippocampal region3.36
4.08
Sdc4sAMYStriatum-like amygdalar nuclei6.9
8.88
Sdc4STRStriatum2.07
2.33
Sdc4STRdStriatum dorsal region0.94
1.11
Sdc4STRvStriatum ventral region4.09
3.45
Sdc4THThalamus1.44
2.07
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved