AutismKB 2.0

Annotation Detail for PRDM1


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Basic Information Top
Gene Symbol:PRDM1 ( BLIMP1,MGC118922,MGC118923,MGC118924,MGC118925,PRDI-BF1 )
Gene Full Name: PR domain containing 1, with ZNF domain
Band: 6q21
Quick LinksEntrez ID:639; OMIM: 603423; Uniprot ID:PRDM1_HUMAN; ENSEMBL ID: ENSG00000057657; HGNC ID: 9346
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor3 / 26384511
glioma1 / 1068839
head and neck tumor14 / 136302102
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal40 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain2 / 11009891
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus1 / 2020949
eye4 / 21105418
heart0 / 896260 
intestine11 / 23447246
kidney3 / 21177714
larynx2 / 2414582
liver1 / 2077434
lung13 / 33697438
lymph0 / 442700 
lymph node7 / 9161076
mammary gland2 / 15327113
mouth11 / 67052164
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate0 / 1893450 
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach3 / 9661931
testis0 / 3304420 
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217192_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.6
Adipocyte8.65
AdrenalCortex9.35
Adrenalgland7.4
Amygdala8.85
Appendix13.9
AtrioventricularNode9.7
BDCA4+_DentriticCells14.8
Bonemarrow12.2
BronchialEpithelialCells8.65
CD105+_Endothelial6.85
CD14+_Monocytes7.45
CD19+_BCells(neg._sel.)9.4
CD33+_Myeloid9.8
CD34+9.35
CD4+_Tcells8.75
CD56+_NKCells12.8
CD71+_EarlyErythroid7.4
CD8+_Tcells8.05
CardiacMyocytes10.5
Caudatenucleus9.05
Cerebellum7.8
CerebellumPeduncles9.95
CiliaryGanglion6.65
CingulateCortex10.45
Colorectaladenocarcinoma8.65
DorsalRootGanglion6.65
FetalThyroid8.95
Fetalbrain8.65
Fetalliver8.3
Fetallung6.65
GlobusPallidus6.5
Heart12.25
Hypothalamus9.4
Kidney7.8
Leukemia_chronicMyelogenousK-5627.85
Leukemia_promyelocytic-HL-606.7
Leukemialymphoblastic(MOLT-4)6.7
Liver12.4
Lung11.05
Lymphnode7.95
Lymphoma_burkitts(Daudi)11
Lymphoma_burkitts(Raji)12.15
MedullaOblongata10.5
OccipitalLobe7.55
OlfactoryBulb6.9
Ovary10.3
Pancreas7.2
PancreaticIslet8.25
ParietalLobe9.55
Pituitary10.15
Placenta10.35
Pons8.65
PrefrontalCortex9.6
Prostate9.25
Salivarygland7.05
SkeletalMuscle19.05
Skin7.05
SmoothMuscle7.55
Spinalcord9.4
SubthalamicNucleus8.15
SuperiorCervicalGanglion31.65
TemporalLobe7.95
Testis7.4
TestisGermCell7.2
TestisIntersitial7.55
TestisLeydigCell10.45
TestisSeminiferousTubule8.75
Thalamus8.9
Thymus6.3
Thyroid11
Tongue10.8
Tonsil10.45
Trachea7.85
TrigeminalGanglion10.15
Uterus7.55
UterusCorpus9.95
WholeBlood11.1
Wholebrain7.35
colon8.8
pineal_day8.82
pineal_night8.96
retina10.65
small_intestine8.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P169550
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.77 ± 0.69
Basal Forebrain2.37 ± 0.44
Basal Part of Pons2.16 ± 0.43
Cerebellar Cortex2.64 ± 0.64
Cerebellar Nuclei2.74 ± 0.54
Claustrum2.91 ± 0.76
Epithalamus2.3 ± 0.55
Frontal Lobe2.56 ± 0.6
Globus Pallidus2.37 ± 0.7
Hypothalamus2.55 ± 0.5
Insula2.7 ± 0.36
Limbic Lobe2.61 ± 0.67
Mesencephalon2.76 ± 0.73
Myelencephalon2.56 ± 0.61
Occipital Lobe2.42 ± 0.77
Parietal Lobe2.76 ± 0.59
Pontine Tegmentum2.59 ± 0.65
Striatum2.59 ± 0.75
Subthalamus2.44 ± 0.63
Temporal Lobe2.57 ± 0.66
Thalamus2.64 ± 0.67
White Matter1.89 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Prdm1CBCerebellum0.67
1.11
Prdm1CTXCerebral cortex0.92
0.85
Prdm1HIPHippocampal region0.76
0.83
Prdm1HPFHippocampal formation0.66
0.72
Prdm1HYHypothalamus0.48
0.46
Prdm1LSXLateral septal complex0.7
0.86
Prdm1MBMidbrain0.42
0.43
Prdm1MYMedulla0.26
0.2
Prdm1OLFOlfactory bulb1.01
1.98
Prdm1PPons0.38
0.29
Prdm1PALPallidum0.21
0.35
Prdm1RHPRetrohippocampal region0.48
0.57
Prdm1sAMYStriatum-like amygdalar nuclei0.26
0.36
Prdm1STRStriatum0.36
0.34
Prdm1STRdStriatum dorsal region0.28
0.2
Prdm1STRvStriatum ventral region0.43
0.5
Prdm1THThalamus0.72
0.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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