AutismKB 2.0

Annotation Detail for NAPB


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Basic Information Top
Gene Symbol:NAPB ( MGC26066,MGC48335,SNAP-BETA,SNAPB )
Gene Full Name: N-ethylmaleimide-sensitive factor attachment protein, beta
Band: 20p11.21
Quick LinksEntrez ID:63908; OMIM: 611270; Uniprot ID:SNAB_HUMAN; ENSEMBL ID: ENSG00000125814; HGNC ID: 15751
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus53 / 56401293
neonate0 / 310970 
infant3 / 23620127
juvenile1 / 5555617
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor13 / 26384549
glioma3 / 10688328
head and neck tumor6 / 13630244
kidney tumor8 / 68959116
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal780 / 3360307232
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma5 / 46356107
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder5 / 29757168
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain725 / 1100989658
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye32 / 211054151
heart5 / 8962655
intestine6 / 23447225
kidney15 / 21177770
larynx0 / 241450 
liver2 / 2077439
lung22 / 33697465
lymph0 / 442700 
lymph node3 / 9161032
mammary gland4 / 15327126
mouth5 / 6705274
muscle3 / 10771527
nerve2 / 15768126
ovary0 / 1020510 
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta10 / 28082535
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis17 / 33044251
thymus6 / 8113173
thyroid0 / 474730 
tonsil0 / 169990 
trachea12 / 52413228
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6536_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.49 ± 0.41
Basal Forebrain8.56 ± 0.37
Basal Part of Pons9.94 ± 0.19
Cerebellar Cortex9.16 ± 0.22
Cerebellar Nuclei9.07 ± 0.41
Claustrum9.59 ± 0.18
Epithalamus7.93 ± 0.95
Frontal Lobe9.3 ± 0.46
Globus Pallidus7.89 ± 0.63
Hypothalamus9 ± 0.55
Insula9.22 ± 0.33
Limbic Lobe9.44 ± 0.46
Mesencephalon8.93 ± 0.64
Myelencephalon9.01 ± 0.7
Occipital Lobe8.84 ± 0.64
Parietal Lobe9.33 ± 0.49
Pontine Tegmentum9.02 ± 0.36
Striatum7.99 ± 0.68
Subthalamus9.54 ± 0.35
Temporal Lobe9.28 ± 0.29
Thalamus8.82 ± 0.42
White Matter6.88 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NapbCBCerebellum100
100
NapbCTXCerebral cortex100
100
NapbHIPHippocampal region100
100
NapbHPFHippocampal formation100
100
NapbHYHypothalamus100
100
NapbLSXLateral septal complex100
100
NapbMBMidbrain100
100
NapbMYMedulla100
100
NapbOLFOlfactory bulb100
100
NapbPPons100
100
NapbPALPallidum100
100
NapbRHPRetrohippocampal region100
100
NapbsAMYStriatum-like amygdalar nuclei100
100
NapbSTRStriatum100
100
NapbSTRdStriatum dorsal region100
95.58
NapbSTRvStriatum ventral region100
100
NapbTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000421 27 141 167 AIAHYEQSADYYKGEESNSSANKCLLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018