AutismKB 2.0

Annotation Detail for ANKRD5


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Basic Information Top
Gene Symbol:ANKRD5 ( FLJ21669,dJ839B4.6 )
Gene Full Name: ankyrin repeat domain 5
Band: 20pter-q11.23
Quick LinksEntrez ID:63926; OMIM: NA; Uniprot ID:ANKR5_HUMAN; ENSEMBL ID: ENSG00000132623; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal32 / 33603079
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain10 / 11009899
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine7 / 23447229
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis17 / 33044251
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220144_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.35
Adipocyte8.8
AdrenalCortex11.15
Adrenalgland7.45
Amygdala7.8
Appendix10.25
AtrioventricularNode8.5
BDCA4+_DentriticCells7.55
Bonemarrow8.95
BronchialEpithelialCells7.65
CD105+_Endothelial7.95
CD14+_Monocytes7.8
CD19+_BCells(neg._sel.)8.1
CD33+_Myeloid9.4
CD34+9.9
CD4+_Tcells8
CD56+_NKCells8.85
CD71+_EarlyErythroid7.4
CD8+_Tcells7.4
CardiacMyocytes13.4
Caudatenucleus7.3
Cerebellum6.8
CerebellumPeduncles10
CiliaryGanglion14.25
CingulateCortex8.65
Colorectaladenocarcinoma8.1
DorsalRootGanglion7.75
FetalThyroid8.25
Fetalbrain7.15
Fetalliver7.35
Fetallung5.9
GlobusPallidus7.15
Heart14.85
Hypothalamus8.7
Kidney7.75
Leukemia_chronicMyelogenousK-5627.25
Leukemia_promyelocytic-HL-607.1
Leukemialymphoblastic(MOLT-4)6
Liver13.05
Lung8.6
Lymphnode6.35
Lymphoma_burkitts(Daudi)10.4
Lymphoma_burkitts(Raji)12.4
MedullaOblongata7.2
OccipitalLobe7.25
OlfactoryBulb6.1
Ovary6.2
Pancreas6.95
PancreaticIslet8.85
ParietalLobe9.95
Pituitary9.45
Placenta7.85
Pons8.2
PrefrontalCortex9.35
Prostate9.15
Salivarygland6.75
SkeletalMuscle28.15
Skin7.65
SmoothMuscle9.05
Spinalcord8.55
SubthalamicNucleus8.45
SuperiorCervicalGanglion15.2
TemporalLobe13.65
Testis6.85
TestisGermCell6.2
TestisIntersitial7
TestisLeydigCell8.4
TestisSeminiferousTubule6.9
Thalamus8.65
Thymus5.55
Thyroid9.45
Tongue10.95
Tonsil7.95
Trachea7
TrigeminalGanglion12.2
Uterus6.25
UterusCorpus8.45
WholeBlood7.95
Wholebrain6.15
colon10.15
pineal_day9.7
pineal_night9.34
retina9.65
small_intestine8.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P365086
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.45 ± 0.91
Basal Forebrain1.86 ± 0.56
Basal Part of Pons2.76 ± 0.61
Cerebellar Cortex3.16 ± 0.45
Cerebellar Nuclei3.49 ± 0.66
Claustrum2.73 ± 0.81
Epithalamus3.72 ± 0.76
Frontal Lobe2.53 ± 0.72
Globus Pallidus2.41 ± 0.55
Hypothalamus2.53 ± 0.61
Insula2.2 ± 0.84
Limbic Lobe2.49 ± 0.75
Mesencephalon2.48 ± 0.7
Myelencephalon2.56 ± 0.79
Occipital Lobe2.6 ± 0.8
Parietal Lobe2.71 ± 0.84
Pontine Tegmentum2.7 ± 0.74
Striatum2.39 ± 0.76
Subthalamus2.58 ± 0.46
Temporal Lobe2.32 ± 0.74
Thalamus3.06 ± 0.75
White Matter1.78 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ankrd5CBCerebellum0
0
Ankrd5CTXCerebral cortex0
0
Ankrd5HIPHippocampal region0
0
Ankrd5HPFHippocampal formation0
0
Ankrd5HYHypothalamus0
0
Ankrd5LSXLateral septal complex0
0
Ankrd5MBMidbrain0
0
Ankrd5MYMedulla0
0
Ankrd5OLFOlfactory bulb0
0
Ankrd5PPons0
0
Ankrd5PALPallidum0
0
Ankrd5RHPRetrohippocampal region0
0
Ankrd5sAMYStriatum-like amygdalar nuclei0
0
Ankrd5STRStriatum0
0
Ankrd5STRdStriatum dorsal region0
0
Ankrd5STRvStriatum ventral region0
0
Ankrd5THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ANKR5_HUMAN_7 9 7 15 RLENLQIYK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018