AutismKB 2.0

Annotation Detail for NECAB3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NECAB3 ( APBA2BP,EFCBP3,NIP1,STIP3,SYTIP2,XB51,dJ63M2.4,dJ63M2.5 )
Gene Full Name: N-terminal EF-hand calcium binding protein 3
Band: 20q11.22
Quick LinksEntrez ID:63941; OMIM: 612478; Uniprot ID:NECA3_HUMAN; ENSEMBL ID: ENSG00000125967; HGNC ID: 15851
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor4 / 34366116
chondrosarcoma7 / 8282384
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor6 / 26384522
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma7 / 7175597
non-neoplasia0 / 972500 
normal117 / 336030734
ovarian tumor3 / 7668239
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor8 / 12494964
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood3 / 12347824
bone6 / 7165583
bone marrow2 / 4880140
brain46 / 110098941
cervix12 / 48171249
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine11 / 23447246
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph3 / 4427067
lymph node0 / 916100 
mammary gland5 / 15327132
mouth2 / 6705229
muscle1 / 1077159
nerve1 / 1576863
ovary8 / 10205178
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta10 / 28082535
prostate9 / 18934547
salivary gland1 / 2015549
skin8 / 21057437
spleen1 / 5395218
stomach6 / 9661962
testis13 / 33044239
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210720_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.7
Adipocyte41.45
AdrenalCortex88.5
Adrenalgland192.85
Amygdala86.3
Appendix77
AtrioventricularNode27.25
BDCA4+_DentriticCells9.45
Bonemarrow29.85
BronchialEpithelialCells20.65
CD105+_Endothelial14.25
CD14+_Monocytes23.75
CD19+_BCells(neg._sel.)16.9
CD33+_Myeloid25.1
CD34+24.1
CD4+_Tcells29.6
CD56+_NKCells18.65
CD71+_EarlyErythroid24.1
CD8+_Tcells12.85
CardiacMyocytes67.85
Caudatenucleus30.7
Cerebellum32.8
CerebellumPeduncles41.75
CiliaryGanglion24.6
CingulateCortex74.25
Colorectaladenocarcinoma55.1
DorsalRootGanglion26.2
FetalThyroid34.2
Fetalbrain46.9
Fetalliver30.55
Fetallung45.05
GlobusPallidus30.55
Heart444.9
Hypothalamus48.6
Kidney49.9
Leukemia_chronicMyelogenousK-56269.2
Leukemia_promyelocytic-HL-6049.6
Leukemialymphoblastic(MOLT-4)27.15
Liver102.4
Lung111.4
Lymphnode19.8
Lymphoma_burkitts(Daudi)59.95
Lymphoma_burkitts(Raji)213.9
MedullaOblongata53.55
OccipitalLobe35.85
OlfactoryBulb22.8
Ovary48.45
Pancreas24.85
PancreaticIslet29.05
ParietalLobe56.9
Pituitary34.6
Placenta19.85
Pons37.25
PrefrontalCortex130.3
Prostate123.8
Salivarygland28.95
SkeletalMuscle149.85
Skin23.45
SmoothMuscle30.6
Spinalcord41.55
SubthalamicNucleus31.9
SuperiorCervicalGanglion39.4
TemporalLobe69.75
Testis114.7
TestisGermCell45.1
TestisIntersitial68.35
TestisLeydigCell42.05
TestisSeminiferousTubule47.5
Thalamus101.4
Thymus28.4
Thyroid73.3
Tongue51.8
Tonsil25.1
Trachea30.5
TrigeminalGanglion46.7
Uterus23.6
UterusCorpus52.3
WholeBlood24.45
Wholebrain251.75
colon40.1
pineal_day87.44
pineal_night49.32
retina66.925
small_intestine37.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11211_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.02 ± 0.83
Basal Forebrain2.56 ± 0.36
Basal Part of Pons2.33 ± 0.43
Cerebellar Cortex2.39 ± 0.59
Cerebellar Nuclei2.87 ± 0.61
Claustrum2.94 ± 0.68
Epithalamus2.61 ± 0.63
Frontal Lobe2.8 ± 0.62
Globus Pallidus2.49 ± 0.49
Hypothalamus2.35 ± 0.67
Insula2.86 ± 0.52
Limbic Lobe2.61 ± 0.63
Mesencephalon2.72 ± 0.71
Myelencephalon2.73 ± 0.6
Occipital Lobe2.53 ± 0.64
Parietal Lobe2.77 ± 0.66
Pontine Tegmentum2.73 ± 0.68
Striatum2.14 ± 0.82
Subthalamus2.98 ± 0.3
Temporal Lobe2.86 ± 0.62
Thalamus2.57 ± 0.62
White Matter1.72 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Apba2bpCBCerebellum13.87
18.18
Apba2bpCTXCerebral cortex48.84
40.93
Apba2bpHIPHippocampal region8.21
8.86
Apba2bpHPFHippocampal formation11.3
10.98
Apba2bpHYHypothalamus6.24
5.6
Apba2bpLSXLateral septal complex1.84
1.5
Apba2bpMBMidbrain7.66
9.14
Apba2bpMYMedulla15.54
22.16
Apba2bpOLFOlfactory bulb41.06
44.7
Apba2bpPPons8.1
12.18
Apba2bpPALPallidum6.05
5.81
Apba2bpRHPRetrohippocampal region16.43
13.99
Apba2bpsAMYStriatum-like amygdalar nuclei6.42
5.08
Apba2bpSTRStriatum6.31
5.04
Apba2bpSTRdStriatum dorsal region5.9
4.5
Apba2bpSTRvStriatum ventral region9.43
7.59
Apba2bpTHThalamus25.24
27.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved