AutismKB 2.0

Annotation Detail for SEC13


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Basic Information Top
Gene Symbol:SEC13 ( D3S1231E,SEC13L1,SEC13R,npp-20 )
Gene Full Name: SEC13 homolog (S. cerevisiae)
Band: 3p25.3
Quick LinksEntrez ID:6396; OMIM: 600152; Uniprot ID:SEC13_HUMAN; ENSEMBL ID: ENSG00000157020; HGNC ID: 10697
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst8 / 62319128
fetus71 / 564012125
neonate2 / 3109764
infant0 / 236200 
juvenile4 / 5555671
adult195 / 1939121100
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma8 / 17475457
breast (mammary gland) tumor6 / 9417863
cervical tumor2 / 3436658
chondrosarcoma12 / 82823144
colorectal tumor13 / 114246113
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor20 / 26384575
glioma12 / 106883112
head and neck tumor30 / 136302220
kidney tumor7 / 68959101
leukemia8 / 9584283
liver tumor14 / 96359145
lung tumor3 / 10312729
lymphoma13 / 71755181
non-neoplasia3 / 9725030
normal379 / 3360307112
ovarian tumor7 / 7668291
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer4 / 10268038
retinoblastoma7 / 46356151
skin tumor14 / 124949112
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland3 / 3319790
ascites6 / 40015149
bladder4 / 29757134
blood10 / 12347880
bone11 / 71655153
bone marrow8 / 48801163
brain74 / 110098967
cervix9 / 48171186
connective tissue8 / 14925553
ear2 / 16212123
embryonic tissue37 / 215722171
esophagus0 / 202090 
eye21 / 21105499
heart14 / 89626156
intestine26 / 234472110
kidney32 / 211777151
larynx0 / 241450 
liver27 / 207743129
lung32 / 33697494
lymph7 / 44270158
lymph node5 / 9161054
mammary gland9 / 15327158
mouth0 / 670520 
muscle8 / 10771574
nerve1 / 1576863
ovary8 / 10205178
pancreas30 / 214812139
parathyroid1 / 2053948
pharynx39 / 41328943
pituitary gland2 / 16585120
placenta30 / 280825106
prostate8 / 18934542
salivary gland2 / 2015599
skin62 / 210574294
spleen4 / 5395274
stomach10 / 96619103
testis22 / 33044266
thymus2 / 8113124
thyroid3 / 4747363
tonsil2 / 16999117
trachea2 / 5241338
umbilical cord2 / 13680146
uterus37 / 232878158
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207707_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts905.6
Adipocyte257.3
AdrenalCortex108.5
Adrenalgland166.5
Amygdala164.1
Appendix67.05
AtrioventricularNode40.2
BDCA4+_DentriticCells804.45
Bonemarrow182.9
BronchialEpithelialCells639.7
CD105+_Endothelial344.3
CD14+_Monocytes799.95
CD19+_BCells(neg._sel.)474.8
CD33+_Myeloid624.85
CD34+543.1
CD4+_Tcells412.15
CD56+_NKCells519.05
CD71+_EarlyErythroid165
CD8+_Tcells294.05
CardiacMyocytes711.65
Caudatenucleus99.3
Cerebellum121.9
CerebellumPeduncles130.55
CiliaryGanglion47.9
CingulateCortex108.95
Colorectaladenocarcinoma478.7
DorsalRootGanglion56
FetalThyroid331
Fetalbrain135.05
Fetalliver220.8
Fetallung317.45
GlobusPallidus68.45
Heart191.05
Hypothalamus237.4
Kidney138.55
Leukemia_chronicMyelogenousK-562644.5
Leukemia_promyelocytic-HL-60175.7
Leukemialymphoblastic(MOLT-4)191.45
Liver463.95
Lung432.55
Lymphnode189.7
Lymphoma_burkitts(Daudi)385.25
Lymphoma_burkitts(Raji)341.75
MedullaOblongata91.2
OccipitalLobe112.9
OlfactoryBulb147.9
Ovary87.85
Pancreas211.75
PancreaticIslet536.85
ParietalLobe84.15
Pituitary444.25
Placenta364.05
Pons61.25
PrefrontalCortex172.4
Prostate506.2
Salivarygland133.5
SkeletalMuscle107.55
Skin58.9
SmoothMuscle1091.25
Spinalcord178.8
SubthalamicNucleus53.9
SuperiorCervicalGanglion55.8
TemporalLobe46.55
Testis294.1
TestisGermCell235.95
TestisIntersitial172.25
TestisLeydigCell155.35
TestisSeminiferousTubule171.35
Thalamus128.2
Thymus344.75
Thyroid496.1
Tongue88
Tonsil212.6
Trachea226.3
TrigeminalGanglion53.2
Uterus359.85
UterusCorpus181.65
WholeBlood267.65
Wholebrain209.25
colon348.95
pineal_day273.16
pineal_night307.38
retina344.425
small_intestine519.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P29555
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.17 ± 0.27
Basal Forebrain10.43 ± 0.22
Basal Part of Pons10.48 ± 0.21
Cerebellar Cortex10.46 ± 0.23
Cerebellar Nuclei10.66 ± 0.18
Claustrum10.02 ± 0.35
Epithalamus10.58 ± 0.25
Frontal Lobe10.55 ± 0.23
Globus Pallidus10.77 ± 0.17
Hypothalamus10.74 ± 0.25
Insula10.67 ± 0.27
Limbic Lobe10.33 ± 0.32
Mesencephalon10.51 ± 0.29
Myelencephalon10.45 ± 0.25
Occipital Lobe10.22 ± 0.25
Parietal Lobe10.43 ± 0.29
Pontine Tegmentum10.51 ± 0.28
Striatum10.61 ± 0.26
Subthalamus10.69 ± 0.18
Temporal Lobe10.45 ± 0.22
Thalamus10.45 ± 0.2
White Matter11.21 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sec13l1CBCerebellum0
0
Sec13l1CTXCerebral cortex0
0
Sec13l1HIPHippocampal region0
0
Sec13l1HPFHippocampal formation0
0
Sec13l1HYHypothalamus0
0
Sec13l1LSXLateral septal complex0
0
Sec13l1MBMidbrain0
0
Sec13l1MYMedulla0
0
Sec13l1OLFOlfactory bulb0
0
Sec13l1PPons0
0
Sec13l1PALPallidum0
0
Sec13l1RHPRetrohippocampal region0
0
Sec13l1sAMYStriatum-like amygdalar nuclei0
0
Sec13l1STRStriatum0
0
Sec13l1STRdStriatum dorsal region0
0
Sec13l1STRvStriatum ventral region0
0
Sec13l1THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002325 11 182 192 FASGGCDNLIK Peptide Atlas
SEC13_HUMAN_1 26 1 26 VSVINTVDTSHEDMIHDAQMDYYGTR PRIDE
SEC13_HUMAN_181 11 181 191 FASGGCDNLIK PRIDE
SEC13_HUMAN_305 17 305 321 GQGSVSASVTEGQQNEQ PRIDE
SEC13_HUMAN_36 8 36 43 SVKIFDVR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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