AutismKB 2.0

Annotation Detail for SEC14L1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SEC14L1 ( DKFZp686C06176,PRELID4A,SEC14L )
Gene Full Name: SEC14-like 1 (S. cerevisiae)
Band: 17q25.2-q25.3
Quick LinksEntrez ID:6397; OMIM: 601504; Uniprot ID:S14L1_HUMAN; ENSEMBL ID: ENSG00000129657; HGNC ID: 10698
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus44 / 56401278
neonate3 / 3109796
infant0 / 236200 
juvenile2 / 5555635
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma15 / 82823181
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor9 / 26384534
glioma13 / 106883121
head and neck tumor9 / 13630266
kidney tumor7 / 68959101
leukemia10 / 95842104
liver tumor1 / 9635910
lung tumor10 / 10312796
lymphoma11 / 71755153
non-neoplasia3 / 9725030
normal297 / 336030788
ovarian tumor5 / 7668265
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites0 / 400150 
bladder2 / 2975767
blood15 / 123478121
bone12 / 71655167
bone marrow4 / 4880181
brain98 / 110098989
cervix1 / 4817120
connective tissue20 / 149255133
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye16 / 21105475
heart7 / 8962678
intestine14 / 23447259
kidney19 / 21177789
larynx0 / 241450 
liver1 / 2077434
lung42 / 336974124
lymph5 / 44270112
lymph node7 / 9161076
mammary gland10 / 15327165
mouth4 / 6705259
muscle10 / 10771592
nerve1 / 1576863
ovary6 / 10205158
pancreas11 / 21481251
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta14 / 28082549
prostate2 / 18934510
salivary gland2 / 2015599
skin15 / 21057471
spleen7 / 53952129
stomach4 / 9661941
testis42 / 330442127
thymus12 / 81131147
thyroid4 / 4747384
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord2 / 13680146
uterus13 / 23287855
vascular14 / 51780270
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202084_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts242.25
Adipocyte59.15
AdrenalCortex236.65
Adrenalgland652.7
Amygdala249.05
Appendix113.3
AtrioventricularNode123.85
BDCA4+_DentriticCells511.05
Bonemarrow263.45
BronchialEpithelialCells119.1
CD105+_Endothelial177.8
CD14+_Monocytes436.85
CD19+_BCells(neg._sel.)184.3
CD33+_Myeloid478.05
CD34+197.95
CD4+_Tcells83.4
CD56+_NKCells329.35
CD71+_EarlyErythroid1153.3
CD8+_Tcells68.8
CardiacMyocytes142.9
Caudatenucleus310.7
Cerebellum503.8
CerebellumPeduncles318.2
CiliaryGanglion86.55
CingulateCortex292.4
Colorectaladenocarcinoma249.4
DorsalRootGanglion113.85
FetalThyroid141.7
Fetalbrain484.4
Fetalliver121.5
Fetallung442.85
GlobusPallidus101.45
Heart133
Hypothalamus293
Kidney182.1
Leukemia_chronicMyelogenousK-562156.55
Leukemia_promyelocytic-HL-60131.8
Leukemialymphoblastic(MOLT-4)77.2
Liver60.95
Lung661.25
Lymphnode203.95
Lymphoma_burkitts(Daudi)937.3
Lymphoma_burkitts(Raji)133.7
MedullaOblongata223
OccipitalLobe209.35
OlfactoryBulb343.95
Ovary43.85
Pancreas77.95
PancreaticIslet162.15
ParietalLobe174.5
Pituitary340.4
Placenta896.75
Pons116.9
PrefrontalCortex819.1
Prostate155.95
Salivarygland133.25
SkeletalMuscle64.5
Skin116.7
SmoothMuscle131.35
Spinalcord247
SubthalamicNucleus193.45
SuperiorCervicalGanglion118.2
TemporalLobe134.3
Testis275.75
TestisGermCell295
TestisIntersitial119.75
TestisLeydigCell153.8
TestisSeminiferousTubule194.35
Thalamus181.05
Thymus148.85
Thyroid166.45
Tongue86.85
Tonsil199
Trachea172.05
TrigeminalGanglion39.15
Uterus142.8
UterusCorpus105
WholeBlood2752.8
Wholebrain460
colon53.25
pineal_day230.14
pineal_night213.94
retina459.2
small_intestine111.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P206960
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.6 ± 0.4
Basal Forebrain9.81 ± 0.16
Basal Part of Pons9.36 ± 0.21
Cerebellar Cortex9.89 ± 0.2
Cerebellar Nuclei9.96 ± 0.36
Claustrum9.2 ± 0.2
Epithalamus9.76 ± 0.31
Frontal Lobe9.85 ± 0.29
Globus Pallidus10.59 ± 0.43
Hypothalamus9.22 ± 0.13
Insula9.84 ± 0.21
Limbic Lobe10.09 ± 0.39
Mesencephalon10.03 ± 0.42
Myelencephalon9.98 ± 0.49
Occipital Lobe10.53 ± 0.54
Parietal Lobe9.97 ± 0.3
Pontine Tegmentum10.19 ± 0.37
Striatum10.91 ± 0.48
Subthalamus9.96 ± 0.43
Temporal Lobe9.85 ± 0.26
Thalamus10.06 ± 0.36
White Matter10.03 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sec14l1CBCerebellum62.5
94.27
Sec14l1CTXCerebral cortex100
100
Sec14l1HIPHippocampal region100
100
Sec14l1HPFHippocampal formation100
100
Sec14l1HYHypothalamus8.17
6.19
Sec14l1LSXLateral septal complex90.86
97.58
Sec14l1MBMidbrain28.43
25.9
Sec14l1MYMedulla24.88
26.99
Sec14l1OLFOlfactory bulb100
100
Sec14l1PPons19.21
20.5
Sec14l1PALPallidum26.06
25.22
Sec14l1RHPRetrohippocampal region100
100
Sec14l1sAMYStriatum-like amygdalar nuclei45.16
40.33
Sec14l1STRStriatum100
100
Sec14l1STRdStriatum dorsal region100
100
Sec14l1STRvStriatum ventral region100
100
Sec14l1THThalamus33.92
31.18
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
S14L1_HUMAN_2 9 2 10 VQKYQSPVR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved