AutismKB 2.0

Annotation Detail for ANO3


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Basic Information Top
Gene Symbol:ANO3 ( C11orf25,TMEM16C )
Gene Full Name: anoctamin 3
Band: 11p14.2
Quick LinksEntrez ID:63982; OMIM: 610110; Uniprot ID:ANO3_HUMAN; ENSEMBL ID: ENSG00000134343; HGNC ID: 14004
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal35 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain24 / 110098921
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215241_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.6
Adipocyte5.65
AdrenalCortex6.45
Adrenalgland5.05
Amygdala87.1
Appendix6.55
AtrioventricularNode5
BDCA4+_DentriticCells5.85
Bonemarrow6.2
BronchialEpithelialCells5.6
CD105+_Endothelial5.7
CD14+_Monocytes6.1
CD19+_BCells(neg._sel.)5.95
CD33+_Myeloid7.1
CD34+6.9
CD4+_Tcells5.95
CD56+_NKCells6.55
CD71+_EarlyErythroid5.5
CD8+_Tcells5.25
CardiacMyocytes8.45
Caudatenucleus1711.45
Cerebellum4.7
CerebellumPeduncles6.75
CiliaryGanglion4.4
CingulateCortex17.85
Colorectaladenocarcinoma5.8
DorsalRootGanglion4.85
FetalThyroid5.65
Fetalbrain11.05
Fetalliver5.2
Fetallung4.5
GlobusPallidus4.55
Heart8.3
Hypothalamus6.85
Kidney5
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.1
Leukemialymphoblastic(MOLT-4)4.45
Liver8.1
Lung6.3
Lymphnode4.8
Lymphoma_burkitts(Daudi)7.5
Lymphoma_burkitts(Raji)8.55
MedullaOblongata504.5
OccipitalLobe48.95
OlfactoryBulb4.6
Ovary4.1
Pancreas4.8
PancreaticIslet6.2
ParietalLobe7.25
Pituitary6.65
Placenta5.75
Pons246
PrefrontalCortex153.5
Prostate6.65
Salivarygland4.75
SkeletalMuscle7.35
Skin4.95
SmoothMuscle6.5
Spinalcord6.15
SubthalamicNucleus6.45
SuperiorCervicalGanglion7.5
TemporalLobe23.85
Testis4.9
TestisGermCell4.65
TestisIntersitial4.85
TestisLeydigCell17.9
TestisSeminiferousTubule4.95
Thalamus6.8
Thymus5.3
Thyroid7.15
Tongue6
Tonsil5.65
Trachea4.8
TrigeminalGanglion6.6
Uterus4.6
UterusCorpus5.45
WholeBlood6.25
Wholebrain19.65
colon5.8
pineal_day7.06
pineal_night6.92
retina6.975
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15930_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.93 ± 1.31
Basal Forebrain7.49 ± 1.15
Basal Part of Pons8.33 ± 0.6
Cerebellar Cortex4.47 ± 0.55
Cerebellar Nuclei5.24 ± 0.83
Claustrum4.46 ± 1.61
Epithalamus5 ± 1
Frontal Lobe6.42 ± 0.71
Globus Pallidus5.2 ± 1.5
Hypothalamus5.23 ± 1.27
Insula6.19 ± 0.45
Limbic Lobe6.68 ± 1.27
Mesencephalon5.52 ± 1.08
Myelencephalon6 ± 1.41
Occipital Lobe4.4 ± 1.91
Parietal Lobe5.82 ± 1.08
Pontine Tegmentum5.45 ± 1.1
Striatum9.81 ± 1.16
Subthalamus5.19 ± 0.94
Temporal Lobe6.21 ± 0.89
Thalamus4.76 ± 1
White Matter2.87 ± 1.4
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ANO3_HUMAN_189 8 189 196 AEGLMLEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018