AutismKB 2.0

Annotation Detail for SEL1L


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Basic Information Top
Gene Symbol:SEL1L ( IBD2,PRO1063,SEL1-LIKE,SEL1L1 )
Gene Full Name: sel-1 suppressor of lin-12-like (C. elegans)
Band: 14q31
Quick LinksEntrez ID:6400; OMIM: 602329; Uniprot ID:SE1L1_HUMAN; ENSEMBL ID: ENSG00000071537; HGNC ID: 10717
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus47 / 56401283
neonate1 / 3109732
infant1 / 2362042
juvenile2 / 5555635
adult148 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma2 / 17475114
breast (mammary gland) tumor15 / 94178159
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor6 / 26384522
glioma3 / 10688328
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma2 / 7175527
non-neoplasia5 / 9725051
normal245 / 336030772
ovarian tumor4 / 7668252
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor9 / 12494972
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites1 / 4001524
bladder3 / 29757100
blood5 / 12347840
bone7 / 7165597
bone marrow5 / 48801102
brain32 / 110098929
cervix1 / 4817120
connective tissue5 / 14925533
ear6 / 16212370
embryonic tissue8 / 21572237
esophagus1 / 2020949
eye10 / 21105447
heart13 / 89626145
intestine11 / 23447246
kidney10 / 21177747
larynx0 / 241450 
liver18 / 20774386
lung33 / 33697497
lymph0 / 442700 
lymph node20 / 91610218
mammary gland21 / 153271137
mouth5 / 6705274
muscle12 / 107715111
nerve0 / 157680 
ovary7 / 10205168
pancreas22 / 214812102
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta34 / 280825121
prostate13 / 18934568
salivary gland0 / 201550 
skin14 / 21057466
spleen0 / 539520 
stomach4 / 9661941
testis5 / 33044215
thymus1 / 8113112
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus23 / 23287898
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202063_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte6.05
AdrenalCortex6.95
Adrenalgland5.1
Amygdala6.35
Appendix6.8
AtrioventricularNode5.5
BDCA4+_DentriticCells6.45
Bonemarrow6.1
BronchialEpithelialCells5.95
CD105+_Endothelial6.2
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.55
CD33+_Myeloid7.85
CD34+7.8
CD4+_Tcells6.6
CD56+_NKCells7.25
CD71+_EarlyErythroid5.7
CD8+_Tcells6
CardiacMyocytes9.4
Caudatenucleus5.5
Cerebellum4.95
CerebellumPeduncles7
CiliaryGanglion4.65
CingulateCortex6.25
Colorectaladenocarcinoma6.05
DorsalRootGanglion5.55
FetalThyroid5.95
Fetalbrain6.1
Fetalliver5.45
Fetallung4.7
GlobusPallidus4.55
Heart8.7
Hypothalamus6.7
Kidney4.9
Leukemia_chronicMyelogenousK-5625.5
Leukemia_promyelocytic-HL-605.4
Leukemialymphoblastic(MOLT-4)4.95
Liver8
Lung6.75
Lymphnode5.15
Lymphoma_burkitts(Daudi)7.9
Lymphoma_burkitts(Raji)8.7
MedullaOblongata5.65
OccipitalLobe5.5
OlfactoryBulb4.85
Ovary4.1
Pancreas5.65
PancreaticIslet6.65
ParietalLobe6.6
Pituitary7.15
Placenta6.15
Pons5.85
PrefrontalCortex7.5
Prostate7.15
Salivarygland5.05
SkeletalMuscle8.15
Skin4.9
SmoothMuscle6.95
Spinalcord6.55
SubthalamicNucleus5.6
SuperiorCervicalGanglion8.05
TemporalLobe5.7
Testis5.2
TestisGermCell5.05
TestisIntersitial5.1
TestisLeydigCell6.3
TestisSeminiferousTubule5.25
Thalamus6.25
Thymus4.8
Thyroid7.35
Tongue6.2
Tonsil5.95
Trachea5.1
TrigeminalGanglion6.9
Uterus5
UterusCorpus5.75
WholeBlood6.7
Wholebrain5.2
colon6.1
pineal_day7.5
pineal_night7.36
retina7.4
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P88411
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.87 ± 0.27
Basal Forebrain8.78 ± 0.19
Basal Part of Pons8.8 ± 0.32
Cerebellar Cortex8.82 ± 0.34
Cerebellar Nuclei8.97 ± 0.28
Claustrum8.98 ± 0.38
Epithalamus8.89 ± 0.33
Frontal Lobe8.93 ± 0.34
Globus Pallidus9 ± 0.17
Hypothalamus9.21 ± 0.38
Insula9.06 ± 0.23
Limbic Lobe8.94 ± 0.32
Mesencephalon9.03 ± 0.29
Myelencephalon8.9 ± 0.31
Occipital Lobe8.93 ± 0.26
Parietal Lobe8.97 ± 0.3
Pontine Tegmentum8.97 ± 0.31
Striatum8.82 ± 0.28
Subthalamus9.11 ± 0.41
Temporal Lobe8.9 ± 0.34
Thalamus8.87 ± 0.28
White Matter9.87 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sel1hCBCerebellum24.82
61.09
Sel1hCTXCerebral cortex78.57
71.88
Sel1hHIPHippocampal region34.85
52.55
Sel1hHPFHippocampal formation32.1
41.56
Sel1hHYHypothalamus13.34
11.84
Sel1hLSXLateral septal complex11.61
9.57
Sel1hMBMidbrain10.15
11.17
Sel1hMYMedulla32.11
40.21
Sel1hOLFOlfactory bulb51.19
49.4
Sel1hPPons17.23
21.18
Sel1hPALPallidum24.44
24.72
Sel1hRHPRetrohippocampal region27
26.08
Sel1hsAMYStriatum-like amygdalar nuclei30.19
22.86
Sel1hSTRStriatum23.02
18.1
Sel1hSTRdStriatum dorsal region22.36
17.59
Sel1hSTRvStriatum ventral region27.02
20.63
Sel1hTHThalamus24.17
24.68
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002754 18 371 388 GDVQAQVGLGQLHLHGGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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