AutismKB 2.0

Annotation Detail for SELPLG


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Basic Information Top
Gene Symbol:SELPLG ( CD162,CLA,PSGL-1,PSGL1 )
Gene Full Name: selectin P ligand
Band: 12q24.11
Quick LinksEntrez ID:6404; OMIM: 600738; Uniprot ID:SELPL_HUMAN; ENSEMBL ID: ENSG00000110876; HGNC ID: 10722
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate7 / 31097225
infant0 / 236200 
juvenile4 / 5555671
adult77 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma5 / 10688346
head and neck tumor0 / 1363020 
kidney tumor8 / 68959116
leukemia24 / 95842250
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma5 / 7175569
non-neoplasia16 / 97250164
normal255 / 336030775
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood68 / 123478550
bone2 / 7165527
bone marrow10 / 48801204
brain99 / 110098989
cervix0 / 481710 
connective tissue16 / 149255107
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart3 / 8962633
intestine9 / 23447238
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung25 / 33697474
lymph1 / 4427022
lymph node3 / 9161032
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen44 / 53952815
stomach1 / 9661910
testis0 / 3304420 
thymus27 / 81131332
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus19 / 23287881
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209879_at
Cell line Expression level Expression bar
721_B_lymphoblasts78.1
Adipocyte4.3
AdrenalCortex4.55
Adrenalgland3.65
Amygdala8
Appendix4.35
AtrioventricularNode3.45
BDCA4+_DentriticCells912.25
Bonemarrow75.7
BronchialEpithelialCells4
CD105+_Endothelial5.2
CD14+_Monocytes728.35
CD19+_BCells(neg._sel.)24.6
CD33+_Myeloid410.95
CD34+91.05
CD4+_Tcells696.25
CD56+_NKCells767.65
CD71+_EarlyErythroid4
CD8+_Tcells510.75
CardiacMyocytes5.45
Caudatenucleus5.1
Cerebellum3.55
CerebellumPeduncles5.35
CiliaryGanglion3.35
CingulateCortex4.45
Colorectaladenocarcinoma4.4
DorsalRootGanglion3.4
FetalThyroid4.2
Fetalbrain4.35
Fetalliver3.7
Fetallung3.65
GlobusPallidus3.2
Heart6.3
Hypothalamus10.7
Kidney3.5
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-603.8
Leukemialymphoblastic(MOLT-4)4.55
Liver5.65
Lung56.35
Lymphnode21.05
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)6.05
MedullaOblongata4
OccipitalLobe4.95
OlfactoryBulb5.3
Ovary2.8
Pancreas3.5
PancreaticIslet4.7
ParietalLobe4.7
Pituitary5.9
Placenta5.45
Pons4.1
PrefrontalCortex5.3
Prostate5.1
Salivarygland3.65
SkeletalMuscle5.15
Skin3.35
SmoothMuscle4.8
Spinalcord22
SubthalamicNucleus4
SuperiorCervicalGanglion5
TemporalLobe4.15
Testis3.75
TestisGermCell3.5
TestisIntersitial3.6
TestisLeydigCell4.25
TestisSeminiferousTubule3.75
Thalamus9.3
Thymus33.5
Thyroid5.4
Tongue4.35
Tonsil5.65
Trachea3.85
TrigeminalGanglion4.3
Uterus3.5
UterusCorpus3.85
WholeBlood1255.4
Wholebrain8.1
colon4.15
pineal_day5.52
pineal_night5.34
retina6.425
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15833_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.39 ± 0.8
Basal Forebrain3.83 ± 0.37
Basal Part of Pons3.39 ± 0.73
Cerebellar Cortex2.72 ± 0.64
Cerebellar Nuclei3.89 ± 0.57
Claustrum3.6 ± 0.65
Epithalamus3.84 ± 0.69
Frontal Lobe3.26 ± 0.83
Globus Pallidus4.95 ± 0.44
Hypothalamus2.83 ± 0.97
Insula3.37 ± 0.92
Limbic Lobe3.6 ± 0.77
Mesencephalon3.57 ± 0.87
Myelencephalon3.54 ± 0.85
Occipital Lobe3.35 ± 1.06
Parietal Lobe3.42 ± 0.71
Pontine Tegmentum3.22 ± 0.76
Striatum3.76 ± 0.71
Subthalamus3.65 ± 0.48
Temporal Lobe3.49 ± 0.79
Thalamus3.24 ± 0.75
White Matter5.34 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SelplCBCerebellum16.27
16.33
SelplCTXCerebral cortex45.54
29.59
SelplHIPHippocampal region37.35
33.78
SelplHPFHippocampal formation43.45
34.05
SelplHYHypothalamus29.12
18.31
SelplLSXLateral septal complex25.76
18.35
SelplMBMidbrain18.69
13.8
SelplMYMedulla18.86
13.7
SelplOLFOlfactory bulb54.92
34.68
SelplPPons22.25
14.54
SelplPALPallidum32.2
23.34
SelplRHPRetrohippocampal region51.44
34.02
SelplsAMYStriatum-like amygdalar nuclei38.83
26.54
SelplSTRStriatum34.35
23.21
SelplSTRdStriatum dorsal region32.91
22.17
SelplSTRvStriatum ventral region39.81
25.82
SelplTHThalamus26.41
14.73
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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