AutismKB 2.0

Annotation Detail for TSPYL2


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Basic Information Top
Gene Symbol:TSPYL2 ( CDA1,CINAP,CTCL,DENTT,HRIHFB2216,NP79,SE204,TSPX )
Gene Full Name: TSPY-like 2
Band: Xp11.22
Quick LinksEntrez ID:64061; OMIM: 300564; Uniprot ID:TSYL2_HUMAN; ENSEMBL ID: ENSG00000184205; HGNC ID: 24358
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus0 / 5640120 
neonate0 / 310970 
infant1 / 2362042
juvenile6 / 55556107
adult182 / 193912193
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor4 / 26384515
glioma7 / 10688365
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia34 / 95842354
liver tumor0 / 963590 
lung tumor13 / 103127126
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal132 / 336030739
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood34 / 123478275
bone0 / 716550 
bone marrow1 / 4880120
brain39 / 110098935
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye19 / 21105490
heart0 / 896260 
intestine13 / 23447255
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung24 / 33697471
lymph2 / 4427045
lymph node0 / 916100 
mammary gland10 / 15327165
mouth3 / 6705244
muscle0 / 1077150 
nerve6 / 15768380
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta2 / 2808257
prostate17 / 18934589
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach8 / 9661982
testis37 / 330442111
thymus1 / 8113112
thyroid5 / 47473105
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218012_at
Cell line Expression level Expression bar
721_B_lymphoblasts22.4
Adipocyte8.75
AdrenalCortex154.7
Adrenalgland48.15
Amygdala182.55
Appendix6.2
AtrioventricularNode20.85
BDCA4+_DentriticCells86.75
Bonemarrow27.25
BronchialEpithelialCells11.3
CD105+_Endothelial12.25
CD14+_Monocytes5.8
CD19+_BCells(neg._sel.)42.65
CD33+_Myeloid7.45
CD34+24.7
CD4+_Tcells126.65
CD56+_NKCells39
CD71+_EarlyErythroid23.7
CD8+_Tcells128.65
CardiacMyocytes9.45
Caudatenucleus108.3
Cerebellum94.95
CerebellumPeduncles135.45
CiliaryGanglion8.25
CingulateCortex135.55
Colorectaladenocarcinoma25.8
DorsalRootGanglion7.65
FetalThyroid12.8
Fetalbrain25.05
Fetalliver11.1
Fetallung17.75
GlobusPallidus81
Heart13.7
Hypothalamus125.75
Kidney6.65
Leukemia_chronicMyelogenousK-56212
Leukemia_promyelocytic-HL-6017.85
Leukemialymphoblastic(MOLT-4)19.9
Liver17.65
Lung27.25
Lymphnode39.2
Lymphoma_burkitts(Daudi)22.55
Lymphoma_burkitts(Raji)18.6
MedullaOblongata102.6
OccipitalLobe78
OlfactoryBulb58.85
Ovary106.85
Pancreas11.85
PancreaticIslet62
ParietalLobe83.9
Pituitary125.3
Placenta6.65
Pons74.45
PrefrontalCortex418.15
Prostate90.45
Salivarygland14.4
SkeletalMuscle5.1
Skin4.45
SmoothMuscle13.4
Spinalcord48.85
SubthalamicNucleus112.15
SuperiorCervicalGanglion23.8
TemporalLobe76.15
Testis122.35
TestisGermCell196.7
TestisIntersitial49.75
TestisLeydigCell59.85
TestisSeminiferousTubule88.25
Thalamus77.1
Thymus20.45
Thyroid36.15
Tongue5.05
Tonsil9.9
Trachea30.25
TrigeminalGanglion21.75
Uterus84.85
UterusCorpus25.95
WholeBlood12.2
Wholebrain147.65
colon6.8
pineal_day50.04
pineal_night47.04
retina45.95
small_intestine8.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P170608
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.94 ± 0.33
Basal Forebrain8.33 ± 0.32
Basal Part of Pons8.02 ± 0.33
Cerebellar Cortex7.97 ± 0.25
Cerebellar Nuclei7.35 ± 0.59
Claustrum8.85 ± 0.55
Epithalamus7.17 ± 0.58
Frontal Lobe7.84 ± 0.41
Globus Pallidus7.16 ± 0.42
Hypothalamus8.16 ± 0.38
Insula8.08 ± 0.42
Limbic Lobe8.62 ± 0.43
Mesencephalon8.18 ± 0.61
Myelencephalon8.11 ± 0.55
Occipital Lobe8.83 ± 0.57
Parietal Lobe8.31 ± 0.5
Pontine Tegmentum8.09 ± 0.57
Striatum8.8 ± 0.5
Subthalamus7.7 ± 0.63
Temporal Lobe8.2 ± 0.44
Thalamus7.77 ± 0.45
White Matter6.18 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tspyl2CBCerebellum64.71
75.36
Tspyl2CTXCerebral cortex100
100
Tspyl2HIPHippocampal region100
100
Tspyl2HPFHippocampal formation100
100
Tspyl2HYHypothalamus100
100
Tspyl2LSXLateral septal complex100
100
Tspyl2MBMidbrain90.77
100
Tspyl2MYMedulla70.79
79.4
Tspyl2OLFOlfactory bulb100
100
Tspyl2PPons78.57
91.83
Tspyl2PALPallidum100
100
Tspyl2RHPRetrohippocampal region100
100
Tspyl2sAMYStriatum-like amygdalar nuclei100
100
Tspyl2STRStriatum100
100
Tspyl2STRdStriatum dorsal region100
100
Tspyl2STRvStriatum ventral region100
100
Tspyl2THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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