Annotation Detail for NPAS3
Basic Information Top
| Gene Symbol: | NPAS3 ( FLJ10003,FLJ11138,FLJ11605,MOP6,PASD6,bHLHe12 ) |
|---|---|
| Gene Full Name: | neuronal PAS domain protein 3 |
| Band: | 14q13.1 |
| Quick Links | Entrez ID:64067; OMIM: 609430; Uniprot ID:NPAS3_HUMAN; ENSEMBL ID: ENSG00000151322; HGNC ID: 19311 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.675475
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 10 / 564012 | 17 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 17 / 1939121 | 8 |  |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 2 / 564012 | 3 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 0 / 1939121 | 0 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 2 / 564012 | 3 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 1 / 1939121 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 11 / 106883 | 102 |  |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 31 / 3360307 | 9 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 9 / 90257 | 99 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 2 / 3360307 | 0 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 3 / 3360307 | 0 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 35 / 1100989 | 31 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 4 / 215722 | 18 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 6 / 102051 | 58 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 0 / 1100989 | 0 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 0 / 330442 | 0 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 220316_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 25.35 | |
| Adipocyte | 25.8 | |
| AdrenalCortex | 29.9 | |
| Adrenalgland | 23 | |
| Amygdala | 85.3 | |
| Appendix | 41.7 | |
| AtrioventricularNode | 28 | |
| BDCA4+_DentriticCells | 24.15 | |
| Bonemarrow | 27.05 | |
| BronchialEpithelialCells | 23.75 | |
| CD105+_Endothelial | 25.15 | |
| CD14+_Monocytes | 28.1 | |
| CD19+_BCells(neg._sel.) | 26.8 | |
| CD33+_Myeloid | 30.4 | |
| CD34+ | 29.5 | |
| CD4+_Tcells | 27.3 | |
| CD56+_NKCells | 29.7 | |
| CD71+_EarlyErythroid | 25.45 | |
| CD8+_Tcells | 21.95 | |
| CardiacMyocytes | 36.2 | |
| Caudatenucleus | 30.15 | |
| Cerebellum | 37.8 | |
| CerebellumPeduncles | 31.6 | |
| CiliaryGanglion | 34.75 | |
| CingulateCortex | 27.4 | |
| Colorectaladenocarcinoma | 27.15 | |
| DorsalRootGanglion | 28 | |
| FetalThyroid | 27.3 | |
| Fetalbrain | 40.6 | |
| Fetalliver | 23.65 | |
| Fetallung | 22.15 | |
| GlobusPallidus | 20.8 | |
| Heart | 35.55 | |
| Hypothalamus | 32.75 | |
| Kidney | 22.35 | |
| Leukemia_chronicMyelogenousK-562 | 24.5 | |
| Leukemia_promyelocytic-HL-60 | 24 | |
| Leukemialymphoblastic(MOLT-4) | 20.3 | |
| Liver | 36.55 | |
| Lung | 28.9 | |
| Lymphnode | 22.4 | |
| Lymphoma_burkitts(Daudi) | 35 | |
| Lymphoma_burkitts(Raji) | 38.65 | |
| MedullaOblongata | 28.4 | |
| OccipitalLobe | 25 | |
| OlfactoryBulb | 21.5 | |
| Ovary | 19.1 | |
| Pancreas | 21.9 | |
| PancreaticIslet | 28.85 | |
| ParietalLobe | 43.85 | |
| Pituitary | 31.7 | |
| Placenta | 27.6 | |
| Pons | 27.15 | |
| PrefrontalCortex | 88.9 | |
| Prostate | 31.45 | |
| Salivarygland | 22.45 | |
| SkeletalMuscle | 31.95 | |
| Skin | 24.35 | |
| SmoothMuscle | 27.6 | |
| Spinalcord | 33.05 | |
| SubthalamicNucleus | 26.8 | |
| SuperiorCervicalGanglion | 46.65 | |
| TemporalLobe | 42.45 | |
| Testis | 22.65 | |
| TestisGermCell | 21.85 | |
| TestisIntersitial | 23.15 | |
| TestisLeydigCell | 28 | |
| TestisSeminiferousTubule | 23.1 | |
| Thalamus | 38.9 | |
| Thymus | 18.75 | |
| Thyroid | 32.45 | |
| Tongue | 27.8 | |
| Tonsil | 26.25 | |
| Trachea | 22.75 | |
| TrigeminalGanglion | 42.15 | |
| Uterus | 22.25 | |
| UterusCorpus | 28.2 | |
| WholeBlood | 27.55 | |
| Wholebrain | 33.5 | |
| colon | 26.75 | |
| pineal_day | 32.32 | |
| pineal_night | 30.68 | |
| retina | 48.4 | |
| small_intestine | 26.05 | |
- Probe name: A_23_P2942
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.46 ± 0.25 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.74 ± 0.26 | |
| Basal Part of Pons | 6.45 ± 0.19 | |
| Cerebellar Cortex | 6.79 ± 0.22 | |
| Cerebellar Nuclei | 6.85 ± 0.35 | |
| Claustrum | 6.67 ± 0.48 | |
| Epithalamus | 7.87 ± 0.27 | |
| Frontal Lobe | 7.14 ± 0.4 | |
| Globus Pallidus | 8.56 ± 0.34 | |
| Hypothalamus | 7.3 ± 0.24 | |
| Insula | 7.22 ± 0.33 | |
| Limbic Lobe | 7.11 ± 0.56 | |
| Mesencephalon | 7.51 ± 0.36 | |
| Myelencephalon | 7.34 ± 0.54 | |
| Occipital Lobe | 7.57 ± 0.48 | |
| Parietal Lobe | 7.28 ± 0.4 | |
| Pontine Tegmentum | 7.41 ± 0.28 | |
| Striatum | 7.59 ± 0.29 | |
| Subthalamus | 7.03 ± 0.22 | |
| Temporal Lobe | 7.19 ± 0.34 | |
| Thalamus | 7.49 ± 0.36 | |
| White Matter | 8.06 ± 0.2 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Npas3 | STRd | Striatum dorsal region | 0.59 | |
| 0.91 | |
Peptide