AutismKB 2.0

Annotation Detail for POPDC2


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Basic Information Top
Gene Symbol:POPDC2 ( POP2 )
Gene Full Name: popeye domain containing 2
Band: 3q13.33
Quick LinksEntrez ID:64091; OMIM: 605823; Uniprot ID:POPD2_HUMAN; ENSEMBL ID: ENSG00000121577; HGNC ID: 17648
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus31 / 56401254
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal84 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain3 / 11009892
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye5 / 21105423
heart48 / 89626535
intestine8 / 23447234
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219647_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.15
Adipocyte5.15
AdrenalCortex5.8
Adrenalgland4.65
Amygdala5.3
Appendix5.8
AtrioventricularNode4.4
BDCA4+_DentriticCells5.5
Bonemarrow5.45
BronchialEpithelialCells5.05
CD105+_Endothelial5.25
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid6.4
CD34+6.4
CD4+_Tcells5.85
CD56+_NKCells6.05
CD71+_EarlyErythroid5
CD8+_Tcells4.8
CardiacMyocytes7.45
Caudatenucleus4.7
Cerebellum4.35
CerebellumPeduncles6.1
CiliaryGanglion4.3
CingulateCortex5.55
Colorectaladenocarcinoma5.25
DorsalRootGanglion4.3
FetalThyroid5.1
Fetalbrain5.05
Fetalliver4.65
Fetallung4.2
GlobusPallidus4
Heart194.6
Hypothalamus5.55
Kidney4.45
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4.15
Liver7.4
Lung5.7
Lymphnode5.65
Lymphoma_burkitts(Daudi)6.8
Lymphoma_burkitts(Raji)7.6
MedullaOblongata4.75
OccipitalLobe4.6
OlfactoryBulb4.1
Ovary3.6
Pancreas4.25
PancreaticIslet5.65
ParietalLobe5.7
Pituitary6.05
Placenta5.25
Pons5.1
PrefrontalCortex6.35
Prostate6.15
Salivarygland4.3
SkeletalMuscle16.3
Skin4.55
SmoothMuscle5.85
Spinalcord5.6
SubthalamicNucleus4.9
SuperiorCervicalGanglion6.65
TemporalLobe5.05
Testis4.5
TestisGermCell4.3
TestisIntersitial4.45
TestisLeydigCell5.65
TestisSeminiferousTubule4.5
Thalamus5.45
Thymus4.05
Thyroid6.55
Tongue5.4
Tonsil5.1
Trachea4.35
TrigeminalGanglion5.65
Uterus4.25
UterusCorpus5
WholeBlood5.75
Wholebrain4.2
colon9
pineal_day6.5
pineal_night7.32
retina6.35
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P257336
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.47 ± 1.06
Basal Forebrain1.97 ± 0.21
Basal Part of Pons1.72 ± 0.35
Cerebellar Cortex2.31 ± 0.69
Cerebellar Nuclei2.36 ± 0.75
Claustrum2.9 ± 0.84
Epithalamus1.76 ± 0.77
Frontal Lobe1.86 ± 0.6
Globus Pallidus2.31 ± 0.43
Hypothalamus2.14 ± 0.66
Insula1.95 ± 0.87
Limbic Lobe1.97 ± 0.6
Mesencephalon2.21 ± 0.67
Myelencephalon2.04 ± 0.65
Occipital Lobe1.96 ± 0.45
Parietal Lobe2.03 ± 0.8
Pontine Tegmentum2.09 ± 0.74
Striatum2 ± 0.63
Subthalamus2.19 ± 0.67
Temporal Lobe1.97 ± 0.75
Thalamus1.97 ± 0.59
White Matter2.55 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Popdc2CBCerebellum4.24
6.62
Popdc2CTXCerebral cortex2.37
2.75
Popdc2HIPHippocampal region0.79
1.54
Popdc2HPFHippocampal formation0.75
1.24
Popdc2HYHypothalamus0.44
0.54
Popdc2LSXLateral septal complex0.46
1.71
Popdc2MBMidbrain0.71
1.25
Popdc2MYMedulla1.6
2.18
Popdc2OLFOlfactory bulb3.31
2.4
Popdc2PPons1.27
1.66
Popdc2PALPallidum0.49
0.54
Popdc2RHPRetrohippocampal region0.65
0.85
Popdc2sAMYStriatum-like amygdalar nuclei0.43
0.53
Popdc2STRStriatum0.66
0.88
Popdc2STRdStriatum dorsal region0.6
0.81
Popdc2STRvStriatum ventral region1.1
0.99
Popdc2THThalamus0.45
0.61
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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