AutismKB 2.0

Annotation Detail for SMOC2


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Basic Information Top
Gene Symbol:SMOC2 ( MST117,MSTP117,MSTP140,SMAP2,bA270C4A.1,bA37D8.1,dJ421D16.1 )
Gene Full Name: SPARC related modular calcium binding 2
Band: 6q27
Quick LinksEntrez ID:64094; OMIM: 607223; Uniprot ID:SMOC2_HUMAN; ENSEMBL ID: ENSG00000112562; HGNC ID: 20323
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult134 / 193912169
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma11 / 82823132
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor4 / 26384515
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia14 / 97250143
normal174 / 336030751
ovarian tumor2 / 7668226
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow0 / 488010 
brain21 / 110098919
cervix0 / 481710 
connective tissue29 / 149255194
ear6 / 16212370
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye28 / 211054132
heart12 / 89626133
intestine21 / 23447289
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary3 / 10205129
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta17 / 28082560
prostate15 / 18934579
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach13 / 96619134
testis47 / 330442142
thymus8 / 8113198
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus35 / 232878150
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5459_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.76 ± 0.99
Basal Forebrain3.6 ± 0.41
Basal Part of Pons4.05 ± 0.44
Cerebellar Cortex2.95 ± 0.41
Cerebellar Nuclei4.44 ± 0.54
Claustrum3.57 ± 0.62
Epithalamus3.16 ± 1.2
Frontal Lobe3.28 ± 0.87
Globus Pallidus4.77 ± 0.57
Hypothalamus2.93 ± 0.89
Insula3.36 ± 0.63
Limbic Lobe3.42 ± 0.79
Mesencephalon3.76 ± 0.86
Myelencephalon3.68 ± 0.92
Occipital Lobe4.02 ± 0.84
Parietal Lobe3.7 ± 0.85
Pontine Tegmentum3.75 ± 0.79
Striatum5.95 ± 0.79
Subthalamus4.18 ± 0.59
Temporal Lobe3.35 ± 0.64
Thalamus3.74 ± 0.72
White Matter3.87 ± 1.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Smoc2CBCerebellum1.93
3.29
Smoc2CTXCerebral cortex12.57
11.56
Smoc2HIPHippocampal region29.93
54.01
Smoc2HPFHippocampal formation18.76
30.43
Smoc2HYHypothalamus0.48
0.51
Smoc2LSXLateral septal complex0.21
0.14
Smoc2MBMidbrain1.35
1.89
Smoc2MYMedulla3.85
4.52
Smoc2OLFOlfactory bulb7.52
7.12
Smoc2PPons1.3
1.74
Smoc2PALPallidum0.2
0.21
Smoc2RHPRetrohippocampal region3.94
4.03
Smoc2sAMYStriatum-like amygdalar nuclei0.79
0.95
Smoc2STRStriatum1.67
1.58
Smoc2STRdStriatum dorsal region2.25
2.18
Smoc2STRvStriatum ventral region0.22
0.19
Smoc2THThalamus2.95
5.51
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018