Annotation Detail for LRRC4
Basic Information Top
| Gene Symbol: | LRRC4 ( MGC133342,MGC133343,NGL-2 ) |
|---|---|
| Gene Full Name: | leucine rich repeat containing 4 |
| Band: | 7q32.1 |
| Quick Links | Entrez ID:64101; OMIM: 610486; Uniprot ID:LRRC4_HUMAN; ENSEMBL ID: ENSG00000128594; HGNC ID: 15586 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.655003
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 15 / 564012 | 26 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 24 / 1939121 | 12 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 2 / 17290 | 115 |  |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 63 / 3360307 | 18 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 |  |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 38 / 1100989 | 34 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 8 / 211054 | 37 | |
| heart | 1 / 89626 | 11 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 9 / 336974 | 26 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 5 / 330442 | 15 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 3 / 51780 | 57 | |
Microarray in - Probe name: CUST_62_PI416383280
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 9.52 ± 0.54 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.97 ± 0.27 | |
| Basal Part of Pons | 8.83 ± 0.39 | |
| Cerebellar Cortex | 9.63 ± 0.16 | |
| Cerebellar Nuclei | 8.67 ± 0.92 | |
| Claustrum | 9.13 ± 0.58 | |
| Epithalamus | 8.63 ± 0.62 | |
| Frontal Lobe | 9.23 ± 0.46 | |
| Globus Pallidus | 7.64 ± 0.52 | |
| Hypothalamus | 8.29 ± 0.6 | |
| Insula | 9.33 ± 0.47 | |
| Limbic Lobe | 9.42 ± 0.71 | |
| Mesencephalon | 8.88 ± 0.66 | |
| Myelencephalon | 9.15 ± 0.55 | |
| Occipital Lobe | 9.97 ± 0.43 | |
| Parietal Lobe | 9.46 ± 0.46 | |
| Pontine Tegmentum | 9.2 ± 0.58 | |
| Striatum | 8.43 ± 0.64 | |
| Subthalamus | 9.01 ± 0.18 | |
| Temporal Lobe | 9.41 ± 0.41 | |
| Thalamus | 8.92 ± 0.44 | |
| White Matter | 6.97 ± 0.29 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Lrrc4 | CB | Cerebellum | 64.79 | |
| 77.35 | | |||
| Lrrc4 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Lrrc4 | HIP | Hippocampal region | 93.22 | |
| 100 | | |||
| Lrrc4 | HPF | Hippocampal formation | 98.36 | |
| 100 | | |||
| Lrrc4 | HY | Hypothalamus | 11.74 | |
| 5.99 | | |||
| Lrrc4 | LSX | Lateral septal complex | 48.22 | |
| 23.76 | | |||
| Lrrc4 | MB | Midbrain | 22.23 | |
| 16.79 | | |||
| Lrrc4 | MY | Medulla | 26.08 | |
| 22.55 | | |||
| Lrrc4 | OLF | Olfactory bulb | 88.25 | |
| 77.04 | | |||
| Lrrc4 | P | Pons | 16.08 | |
| 13.29 | | |||
| Lrrc4 | PAL | Pallidum | 25.98 | |
| 16.69 | | |||
| Lrrc4 | RHP | Retrohippocampal region | 100 | |
| 90.67 | | |||
| Lrrc4 | sAMY | Striatum-like amygdalar nuclei | 44.32 | |
| 25.44 | | |||
| Lrrc4 | STR | Striatum | 45.12 | |
| 24.4 | | |||
| Lrrc4 | STRd | Striatum dorsal region | 46.39 | |
| 25.59 | | |||
| Lrrc4 | STRv | Striatum ventral region | 43.07 | |
| 21.86 | | |||
| Lrrc4 | TH | Thalamus | 19.14 | |
| 16.71 | |