AutismKB 2.0

Annotation Detail for DUS1L


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Basic Information Top
Gene Symbol:DUS1L ( DUS1,PP3111 )
Gene Full Name: dihydrouridine synthase 1-like (S. cerevisiae)
Band: 17q25.3
Quick LinksEntrez ID:64118; OMIM: NA; Uniprot ID:DUS1L_HUMAN; ENSEMBL ID: ENSG00000169718; HGNC ID: 30086
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus28 / 56401249
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult152 / 193912178
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor7 / 34366203
chondrosarcoma6 / 8282372
colorectal tumor17 / 114246148
esophageal tumor0 / 172900 
gastrointestinal tumor17 / 119369142
germ cell tumor17 / 26384564
glioma15 / 106883140
head and neck tumor12 / 13630288
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor15 / 96359155
lung tumor15 / 103127145
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal164 / 336030748
ovarian tumor11 / 76682143
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer7 / 10268068
retinoblastoma6 / 46356129
skin tumor19 / 124949152
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites14 / 40015349
bladder0 / 297570 
blood7 / 12347856
bone2 / 7165527
bone marrow4 / 4880181
brain46 / 110098941
cervix10 / 48171207
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus2 / 2020998
eye15 / 21105471
heart3 / 8962633
intestine25 / 234472106
kidney5 / 21177723
larynx1 / 2414541
liver19 / 20774391
lung22 / 33697465
lymph2 / 4427045
lymph node6 / 9161065
mammary gland7 / 15327145
mouth1 / 6705214
muscle6 / 10771555
nerve0 / 157680 
ovary19 / 102051186
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta28 / 28082599
prostate12 / 18934563
salivary gland4 / 20155198
skin22 / 210574104
spleen4 / 5395274
stomach5 / 9661951
testis14 / 33044242
thymus1 / 8113112
thyroid8 / 47473168
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus24 / 232878103
vascular1 / 5178019
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217912_at
Cell line Expression level Expression bar
721_B_lymphoblasts111.65
Adipocyte12.2
AdrenalCortex14.25
Adrenalgland10.9
Amygdala12.95
Appendix12.8
AtrioventricularNode10.7
BDCA4+_DentriticCells121.55
Bonemarrow13.55
BronchialEpithelialCells12.85
CD105+_Endothelial119.65
CD14+_Monocytes44.45
CD19+_BCells(neg._sel.)99.15
CD33+_Myeloid62.6
CD34+123.15
CD4+_Tcells144.85
CD56+_NKCells78.05
CD71+_EarlyErythroid98.05
CD8+_Tcells178.05
CardiacMyocytes15.35
Caudatenucleus11.35
Cerebellum10.35
CerebellumPeduncles14.45
CiliaryGanglion9.25
CingulateCortex13.1
Colorectaladenocarcinoma55.6
DorsalRootGanglion9.95
FetalThyroid12.6
Fetalbrain12.95
Fetalliver11.15
Fetallung10.2
GlobusPallidus9.65
Heart16.55
Hypothalamus13.95
Kidney13.7
Leukemia_chronicMyelogenousK-56218
Leukemia_promyelocytic-HL-6019.7
Leukemialymphoblastic(MOLT-4)35.3
Liver52.15
Lung16.95
Lymphnode15.9
Lymphoma_burkitts(Daudi)42.7
Lymphoma_burkitts(Raji)22.95
MedullaOblongata11.6
OccipitalLobe10.8
OlfactoryBulb9.95
Ovary8.4
Pancreas12.6
PancreaticIslet14.15
ParietalLobe13.5
Pituitary14.4
Placenta11.9
Pons11.9
PrefrontalCortex18.35
Prostate15.8
Salivarygland11.25
SkeletalMuscle14.95
Skin10.4
SmoothMuscle11.15
Spinalcord13.2
SubthalamicNucleus14.7
SuperiorCervicalGanglion14.55
TemporalLobe11.55
Testis19.35
TestisGermCell17.35
TestisIntersitial11.5
TestisLeydigCell12.9
TestisSeminiferousTubule22.45
Thalamus13.1
Thymus15.95
Thyroid16.3
Tongue12.95
Tonsil14.3
Trachea10.5
TrigeminalGanglion12.6
Uterus9.5
UterusCorpus11.3
WholeBlood17.05
Wholebrain13.55
colon13.4
pineal_day16.74
pineal_night15.78
retina15.525
small_intestine12.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1542_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.15 ± 0.8
Basal Forebrain9.61 ± 0.38
Basal Part of Pons10.14 ± 0.45
Cerebellar Cortex9.87 ± 0.54
Cerebellar Nuclei9.89 ± 0.72
Claustrum9.76 ± 0.39
Epithalamus9.41 ± 1.53
Frontal Lobe9.03 ± 0.8
Globus Pallidus10.61 ± 0.89
Hypothalamus8.51 ± 0.99
Insula8.56 ± 0.69
Limbic Lobe8.88 ± 0.7
Mesencephalon9.51 ± 0.93
Myelencephalon9.37 ± 0.83
Occipital Lobe10.15 ± 0.8
Parietal Lobe9.44 ± 0.9
Pontine Tegmentum9.2 ± 0.96
Striatum9.86 ± 1.17
Subthalamus10.26 ± 0.13
Temporal Lobe8.92 ± 0.95
Thalamus9.65 ± 0.52
White Matter10 ± 0.77
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dus1lCBCerebellum29.01
33.79
Dus1lCTXCerebral cortex71.73
56.12
Dus1lHIPHippocampal region61.7
84.8
Dus1lHPFHippocampal formation73.8
83.78
Dus1lHYHypothalamus52.76
43.48
Dus1lLSXLateral septal complex18.35
11.76
Dus1lMBMidbrain40.03
37.9
Dus1lMYMedulla49.89
63.33
Dus1lOLFOlfactory bulb64.68
57.98
Dus1lPPons52.34
62.31
Dus1lPALPallidum44.29
44.56
Dus1lRHPRetrohippocampal region100
87.95
Dus1lsAMYStriatum-like amygdalar nuclei81.78
66.89
Dus1lSTRStriatum45.48
36.11
Dus1lSTRdStriatum dorsal region36.71
28.69
Dus1lSTRvStriatum ventral region55.16
42.73
Dus1lTHThalamus54.43
46.33
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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