AutismKB 2.0

Annotation Detail for ZNF674


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Basic Information Top
Gene Symbol:ZNF674 ( DKFZp686H0940,MRX92,ZNF673B )
Gene Full Name: zinc finger protein 674
Band: Xp11.3
Quick LinksEntrez ID:641339; OMIM: 300573; Uniprot ID:ZN674_HUMAN; ENSEMBL ID: ENSG00000251192; HGNC ID: 17625
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult6 / 19391213
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain7 / 11009896
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215309_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.45
Adipocyte8.05
AdrenalCortex13.7
Adrenalgland7.8
Amygdala8
Appendix11.9
AtrioventricularNode12.45
BDCA4+_DentriticCells7.55
Bonemarrow9.8
BronchialEpithelialCells7.7
CD105+_Endothelial8.15
CD14+_Monocytes8.95
CD19+_BCells(neg._sel.)8.35
CD33+_Myeloid9.7
CD34+9.6
CD4+_Tcells7.9
CD56+_NKCells8.75
CD71+_EarlyErythroid8.1
CD8+_Tcells7.1
CardiacMyocytes17.6
Caudatenucleus7.5
Cerebellum6.85
CerebellumPeduncles10.7
CiliaryGanglion9.85
CingulateCortex9.1
Colorectaladenocarcinoma8.2
DorsalRootGanglion9.95
FetalThyroid9.6
Fetalbrain7.75
Fetalliver7.3
Fetallung5.9
GlobusPallidus7.9
Heart15.9
Hypothalamus8.2
Kidney8.05
Leukemia_chronicMyelogenousK-5627.3
Leukemia_promyelocytic-HL-607.25
Leukemialymphoblastic(MOLT-4)6.1
Liver14.1
Lung8.9
Lymphnode6.55
Lymphoma_burkitts(Daudi)11.35
Lymphoma_burkitts(Raji)13.45
MedullaOblongata7.15
OccipitalLobe7.3
OlfactoryBulb6.3
Ovary6.7
Pancreas7.25
PancreaticIslet9.05
ParietalLobe9.95
Pituitary9.8
Placenta7.9
Pons8.6
PrefrontalCortex9.3
Prostate9.2
Salivarygland7.4
SkeletalMuscle14.75
Skin8.9
SmoothMuscle9.3
Spinalcord8.7
SubthalamicNucleus9.15
SuperiorCervicalGanglion19.9
TemporalLobe8.1
Testis7
TestisGermCell6.4
TestisIntersitial7.7
TestisLeydigCell9.05
TestisSeminiferousTubule7.1
Thalamus8.8
Thymus6.1
Thyroid9.45
Tongue10.4
Tonsil8.45
Trachea6.8
TrigeminalGanglion20.2
Uterus6.35
UterusCorpus9.25
WholeBlood8.9
Wholebrain6.3
colon8.15
pineal_day9.96
pineal_night9.68
retina9.9
small_intestine7.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P92558
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.52 ± 0.76
Basal Forebrain3.37 ± 0.33
Basal Part of Pons3.05 ± 0.65
Cerebellar Cortex3.25 ± 0.59
Cerebellar Nuclei3.22 ± 0.59
Claustrum3.37 ± 0.54
Epithalamus3.33 ± 0.27
Frontal Lobe3.01 ± 0.67
Globus Pallidus3.15 ± 0.55
Hypothalamus3.16 ± 0.84
Insula2.94 ± 0.83
Limbic Lobe3.1 ± 0.59
Mesencephalon3.25 ± 0.65
Myelencephalon3.07 ± 0.64
Occipital Lobe3.01 ± 0.73
Parietal Lobe3.22 ± 0.62
Pontine Tegmentum3.14 ± 0.68
Striatum3.07 ± 0.7
Subthalamus3.54 ± 0.58
Temporal Lobe3.11 ± 0.57
Thalamus3.02 ± 0.63
White Matter3.13 ± 0.91
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018