AutismKB 2.0

Annotation Detail for IFIH1


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Basic Information Top
Gene Symbol:IFIH1 ( Hlcd,IDDM19,MDA-5,MDA5,MGC133047 )
Gene Full Name: interferon induced with helicase C domain 1
Band: 2q24.2
Quick LinksEntrez ID:64135; OMIM: 606951; Uniprot ID:IFIH1_HUMAN; ENSEMBL ID: ENSG00000115267; HGNC ID: 18873
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate3 / 3109796
infant0 / 236200 
juvenile2 / 5555635
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor3 / 3436687
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal60 / 336030717
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood6 / 12347848
bone2 / 7165527
bone marrow0 / 488010 
brain10 / 11009899
cervix3 / 4817162
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine8 / 23447234
kidney3 / 21177714
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph1 / 4427022
lymph node3 / 9161032
mammary gland11 / 15327171
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach3 / 9661931
testis4 / 33044212
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus27 / 232878115
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219209_at
Cell line Expression level Expression bar
721_B_lymphoblasts144.3
Adipocyte10.8
AdrenalCortex20.7
Adrenalgland11.35
Amygdala9.7
Appendix18.8
AtrioventricularNode19.3
BDCA4+_DentriticCells41.15
Bonemarrow15
BronchialEpithelialCells10
CD105+_Endothelial15.4
CD14+_Monocytes35.95
CD19+_BCells(neg._sel.)45.35
CD33+_Myeloid18.05
CD34+15.2
CD4+_Tcells24.6
CD56+_NKCells17.5
CD71+_EarlyErythroid12.6
CD8+_Tcells42.85
CardiacMyocytes26.15
Caudatenucleus10.15
Cerebellum9.25
CerebellumPeduncles17
CiliaryGanglion15.2
CingulateCortex12.6
Colorectaladenocarcinoma12.35
DorsalRootGanglion16
FetalThyroid13.25
Fetalbrain11.55
Fetalliver10.45
Fetallung7.8
GlobusPallidus11.45
Heart23.35
Hypothalamus11.45
Kidney12.5
Leukemia_chronicMyelogenousK-56210.6
Leukemia_promyelocytic-HL-6013.5
Leukemialymphoblastic(MOLT-4)9.55
Liver20.3
Lung11.85
Lymphnode23.8
Lymphoma_burkitts(Daudi)40.7
Lymphoma_burkitts(Raji)20.7
MedullaOblongata11.45
OccipitalLobe10.2
OlfactoryBulb14.65
Ovary10.55
Pancreas10.95
PancreaticIslet16.15
ParietalLobe15.05
Pituitary26.2
Placenta11
Pons15.55
PrefrontalCortex12.85
Prostate12
Salivarygland10.5
SkeletalMuscle27.1
Skin17.5
SmoothMuscle12.55
Spinalcord11.8
SubthalamicNucleus13.25
SuperiorCervicalGanglion22.85
TemporalLobe11.55
Testis9.05
TestisGermCell8.05
TestisIntersitial10.2
TestisLeydigCell14.2
TestisSeminiferousTubule9.7
Thalamus13.05
Thymus8.1
Thyroid14.2
Tongue18
Tonsil15.6
Trachea10.1
TrigeminalGanglion21.9
Uterus11.75
UterusCorpus14.85
WholeBlood36.1
Wholebrain8.5
colon11.5
pineal_day13.9
pineal_night12.66
retina13.425
small_intestine9.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16012_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.27 ± 0.36
Basal Forebrain5.53 ± 0.4
Basal Part of Pons4.79 ± 0.54
Cerebellar Cortex4.74 ± 0.33
Cerebellar Nuclei5.7 ± 0.26
Claustrum5.06 ± 0.55
Epithalamus6.18 ± 0.54
Frontal Lobe5.41 ± 0.62
Globus Pallidus6.82 ± 0.32
Hypothalamus5.27 ± 0.64
Insula5.13 ± 0.24
Limbic Lobe4.94 ± 0.62
Mesencephalon5.54 ± 0.46
Myelencephalon5.48 ± 0.67
Occipital Lobe5.54 ± 0.52
Parietal Lobe5.22 ± 0.54
Pontine Tegmentum5.37 ± 0.67
Striatum5.86 ± 0.42
Subthalamus5.41 ± 0.71
Temporal Lobe5.09 ± 0.53
Thalamus5.67 ± 0.41
White Matter6.54 ± 0.41
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00026938 17 909 925 NCSVLACSGEDIHVIEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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