AutismKB 2.0

Annotation Detail for ZFYVE20


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Basic Information Top
Gene Symbol:ZFYVE20 ( FLJ34993,MGC126210,Rabenosyn-5 )
Gene Full Name: zinc finger, FYVE domain containing 20
Band: 3p25.1
Quick LinksEntrez ID:64145; OMIM: 609511; Uniprot ID:RBNS5_HUMAN; ENSEMBL ID: ENSG00000131381; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus37 / 56401265
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor15 / 26384556
glioma7 / 10688365
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal107 / 336030731
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma4 / 4635686
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone1 / 7165513
bone marrow0 / 488010 
brain46 / 110098941
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye15 / 21105471
heart4 / 8962644
intestine5 / 23447221
kidney5 / 21177723
larynx1 / 2414541
liver1 / 2077434
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate9 / 18934547
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P85181
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.1 ± 0.4
Basal Forebrain8.23 ± 0.12
Basal Part of Pons8.4 ± 0.24
Cerebellar Cortex8.18 ± 0.68
Cerebellar Nuclei8.15 ± 0.38
Claustrum7.95 ± 0.78
Epithalamus7.92 ± 0.54
Frontal Lobe8.39 ± 0.39
Globus Pallidus8.32 ± 0.17
Hypothalamus8.18 ± 0.58
Insula8.51 ± 0.29
Limbic Lobe8.06 ± 0.52
Mesencephalon8.26 ± 0.49
Myelencephalon8.2 ± 0.52
Occipital Lobe7.79 ± 0.52
Parietal Lobe8.26 ± 0.4
Pontine Tegmentum8.26 ± 0.33
Striatum7.98 ± 0.32
Subthalamus8.8 ± 0.15
Temporal Lobe8.4 ± 0.41
Thalamus8.23 ± 0.41
White Matter8.49 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfyve20CBCerebellum53.02
80.29
Zfyve20CTXCerebral cortex100
100
Zfyve20HIPHippocampal region95.53
100
Zfyve20HPFHippocampal formation100
100
Zfyve20HYHypothalamus92.07
83.1
Zfyve20LSXLateral septal complex100
100
Zfyve20MBMidbrain93.8
92.12
Zfyve20MYMedulla72.08
83.73
Zfyve20OLFOlfactory bulb100
100
Zfyve20PPons80.42
91.68
Zfyve20PALPallidum89.42
88.22
Zfyve20RHPRetrohippocampal region100
100
Zfyve20sAMYStriatum-like amygdalar nuclei94.44
73.31
Zfyve20STRStriatum100
87.14
Zfyve20STRdStriatum dorsal region100
87.21
Zfyve20STRvStriatum ventral region100
89.14
Zfyve20THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
RBNS5_HUMAN_2 10 2 11 ASLDDPGEVR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018