AutismKB 2.0

Annotation Detail for DPEP2


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Basic Information Top
Gene Symbol:DPEP2 ( MBD2 )
Gene Full Name: dipeptidase 2
Band: 16q22.1
Quick LinksEntrez ID:64174; OMIM: 609925; Uniprot ID:DPEP2_HUMAN; ENSEMBL ID: ENSG00000167261; HGNC ID: 23028
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal65 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood17 / 123478137
bone1 / 7165513
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine4 / 23447217
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node2 / 9161021
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta10 / 28082535
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen6 / 53952111
stomach0 / 966190 
testis2 / 3304426
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219452_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.35
Adipocyte3.45
AdrenalCortex3.6
Adrenalgland2.9
Amygdala3.6
Appendix3.5
AtrioventricularNode2.65
BDCA4+_DentriticCells38.35
Bonemarrow3.45
BronchialEpithelialCells3.45
CD105+_Endothelial3.65
CD14+_Monocytes382.1
CD19+_BCells(neg._sel.)171.95
CD33+_Myeloid233.15
CD34+5.9
CD4+_Tcells149.5
CD56+_NKCells161.05
CD71+_EarlyErythroid3.25
CD8+_Tcells139.55
CardiacMyocytes4.45
Caudatenucleus3.1
Cerebellum2.8
CerebellumPeduncles3.95
CiliaryGanglion2.55
CingulateCortex3.5
Colorectaladenocarcinoma3.45
DorsalRootGanglion2.65
FetalThyroid3.35
Fetalbrain3.5
Fetalliver3
Fetallung2.9
GlobusPallidus2.5
Heart4.4
Hypothalamus3.8
Kidney2.8
Leukemia_chronicMyelogenousK-5623.15
Leukemia_promyelocytic-HL-603.1
Leukemialymphoblastic(MOLT-4)2.8
Liver4.55
Lung4.25
Lymphnode6.6
Lymphoma_burkitts(Daudi)4.4
Lymphoma_burkitts(Raji)4.85
MedullaOblongata3.15
OccipitalLobe3.1
OlfactoryBulb2.75
Ovary2.25
Pancreas2.75
PancreaticIslet3.7
ParietalLobe3.65
Pituitary4.05
Placenta21.75
Pons3.3
PrefrontalCortex4.3
Prostate4.1
Salivarygland2.75
SkeletalMuscle4
Skin2.7
SmoothMuscle3.95
Spinalcord3.7
SubthalamicNucleus3.15
SuperiorCervicalGanglion3.9
TemporalLobe3.15
Testis3
TestisGermCell2.9
TestisIntersitial2.9
TestisLeydigCell3.45
TestisSeminiferousTubule2.95
Thalamus3.55
Thymus2.8
Thyroid4.4
Tongue4
Tonsil3.35
Trachea2.9
TrigeminalGanglion3.45
Uterus2.85
UterusCorpus3.1
WholeBlood501.8
Wholebrain2.95
colon3.5
pineal_day4.34
pineal_night4.26
retina4.2
small_intestine3.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9364_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.24 ± 0.92
Basal Forebrain1.7 ± 0.33
Basal Part of Pons1.78 ± 0.83
Cerebellar Cortex1.78 ± 0.84
Cerebellar Nuclei2.35 ± 0.8
Claustrum2.81 ± 1.02
Epithalamus1.82 ± 0.83
Frontal Lobe1.81 ± 0.74
Globus Pallidus2.37 ± 0.54
Hypothalamus1.84 ± 0.54
Insula1.59 ± 0.47
Limbic Lobe1.89 ± 0.8
Mesencephalon2.18 ± 0.77
Myelencephalon1.99 ± 0.69
Occipital Lobe2.14 ± 0.74
Parietal Lobe2.04 ± 0.81
Pontine Tegmentum2.03 ± 0.73
Striatum2.36 ± 0.71
Subthalamus2.54 ± 1.23
Temporal Lobe1.92 ± 0.78
Thalamus2.01 ± 0.58
White Matter2.27 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpep2CBCerebellum0.27
0.54
Dpep2CTXCerebral cortex0.39
0.62
Dpep2HIPHippocampal region0.3
0.39
Dpep2HPFHippocampal formation0.22
0.28
Dpep2HYHypothalamus0.36
0.33
Dpep2LSXLateral septal complex0.16
0.18
Dpep2MBMidbrain0.42
0.51
Dpep2MYMedulla0.16
0.28
Dpep2OLFOlfactory bulb0.74
2.39
Dpep2PPons0.14
0.23
Dpep2PALPallidum0.28
0.24
Dpep2RHPRetrohippocampal region0.08
0.14
Dpep2sAMYStriatum-like amygdalar nuclei0.74
0.55
Dpep2STRStriatum0.26
0.21
Dpep2STRdStriatum dorsal region0.22
0.17
Dpep2STRvStriatum ventral region0.24
0.27
Dpep2THThalamus0.28
0.37
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025593 18 228 245 GVHSFYNNISGLTDFGEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018