AutismKB 2.0

Annotation Detail for SET


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Basic Information Top
Gene Symbol:SET ( 2PP2A,I2PP2A,IGAAD,IPP2A2,PHAPII,TAF-I,TAF-IBETA )
Gene Full Name: SET nuclear oncogene
Band: 9q34.11
Quick LinksEntrez ID:6418; OMIM: 600960; Uniprot ID:SET_HUMAN; ENSEMBL ID: ENSG00000119335; HGNC ID: 10760
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body11 / 70761155
blastocyst14 / 62319224
fetus65 / 564012115
neonate1 / 3109732
infant0 / 236200 
juvenile6 / 55556107
adult237 / 1939121122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor12 / 94178127
cervical tumor7 / 34366203
chondrosarcoma43 / 82823519
colorectal tumor15 / 114246131
esophageal tumor1 / 1729057
gastrointestinal tumor14 / 119369117
germ cell tumor43 / 263845162
glioma12 / 106883112
head and neck tumor8 / 13630258
kidney tumor12 / 68959174
leukemia12 / 95842125
liver tumor12 / 96359124
lung tumor26 / 103127252
lymphoma7 / 7175597
non-neoplasia3 / 9725030
normal266 / 336030779
ovarian tumor5 / 7668265
pancreatic tumor35 / 104616334
primitive neuroectodermal tumor of the CNS24 / 125680190
prostate cancer19 / 102680185
retinoblastoma5 / 46356107
skin tumor19 / 124949152
soft tissue/muscle tissue tumor21 / 125191167
uterine tumor24 / 90257265
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites6 / 40015149
bladder7 / 29757235
blood12 / 12347897
bone29 / 71655404
bone marrow6 / 48801122
brain62 / 110098956
cervix7 / 48171145
connective tissue24 / 149255160
ear11 / 16212678
embryonic tissue45 / 215722208
esophagus1 / 2020949
eye24 / 211054113
heart11 / 89626122
intestine26 / 234472110
kidney24 / 211777113
larynx2 / 2414582
liver30 / 207743144
lung65 / 336974192
lymph3 / 4427067
lymph node4 / 9161043
mammary gland17 / 153271110
mouth2 / 6705229
muscle6 / 10771555
nerve1 / 1576863
ovary7 / 10205168
pancreas43 / 214812200
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta14 / 28082549
prostate26 / 189345137
salivary gland2 / 2015599
skin23 / 210574109
spleen4 / 5395274
stomach11 / 96619113
testis28 / 33044284
thymus1 / 8113112
thyroid4 / 4747384
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord2 / 13680146
uterus44 / 232878188
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215780_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts951.9
Adipocyte23.8
AdrenalCortex13
Adrenalgland20.6
Amygdala105.35
Appendix18.55
AtrioventricularNode14.4
BDCA4+_DentriticCells425.55
Bonemarrow49.25
BronchialEpithelialCells339.6
CD105+_Endothelial176.15
CD14+_Monocytes96.7
CD19+_BCells(neg._sel.)240.1
CD33+_Myeloid91
CD34+405.8
CD4+_Tcells161.75
CD56+_NKCells335.7
CD71+_EarlyErythroid117
CD8+_Tcells158.7
CardiacMyocytes32.35
Caudatenucleus21.85
Cerebellum14.6
CerebellumPeduncles18.9
CiliaryGanglion11.9
CingulateCortex26.9
Colorectaladenocarcinoma410.8
DorsalRootGanglion10.55
FetalThyroid22.7
Fetalbrain88.85
Fetalliver45.8
Fetallung74.1
GlobusPallidus8.1
Heart13.2
Hypothalamus25.95
Kidney18.05
Leukemia_chronicMyelogenousK-562268.75
Leukemia_promyelocytic-HL-60255.85
Leukemialymphoblastic(MOLT-4)416.1
Liver12.55
Lung67.15
Lymphnode41.55
Lymphoma_burkitts(Daudi)95.25
Lymphoma_burkitts(Raji)210.9
MedullaOblongata18.45
OccipitalLobe19.15
OlfactoryBulb45.1
Ovary19.95
Pancreas36.15
PancreaticIslet36.9
ParietalLobe19
Pituitary29.95
Placenta72.7
Pons17.95
PrefrontalCortex55.95
Prostate143.05
Salivarygland20.4
SkeletalMuscle22.05
Skin11.5
SmoothMuscle37.65
Spinalcord16.55
SubthalamicNucleus15.85
SuperiorCervicalGanglion11.4
TemporalLobe13.4
Testis17.9
TestisGermCell26.9
TestisIntersitial15.6
TestisLeydigCell17.9
TestisSeminiferousTubule25.3
Thalamus14.15
Thymus253.4
Thyroid103.7
Tongue18.65
Tonsil113.15
Trachea78.75
TrigeminalGanglion8.75
Uterus112.4
UterusCorpus15.35
WholeBlood116.1
Wholebrain83.55
colon162.45
pineal_day76.84
pineal_night72.82
retina34.975
small_intestine167.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P217015
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.67 ± 0.27
Basal Forebrain8.68 ± 0.16
Basal Part of Pons8.34 ± 0.25
Cerebellar Cortex8.48 ± 0.48
Cerebellar Nuclei8.57 ± 0.28
Claustrum8.77 ± 0.24
Epithalamus8.62 ± 0.46
Frontal Lobe8.45 ± 0.34
Globus Pallidus9.07 ± 0.27
Hypothalamus8.33 ± 0.34
Insula8.41 ± 0.29
Limbic Lobe8.59 ± 0.34
Mesencephalon8.53 ± 0.27
Myelencephalon8.52 ± 0.33
Occipital Lobe8.55 ± 0.27
Parietal Lobe8.53 ± 0.28
Pontine Tegmentum8.62 ± 0.29
Striatum8.69 ± 0.24
Subthalamus8.46 ± 0.19
Temporal Lobe8.58 ± 0.31
Thalamus8.48 ± 0.31
White Matter9.31 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
SetCBCerebellum32.59
59.93
SetCTXCerebral cortex100
100
SetHIPHippocampal region100
100
SetHPFHippocampal formation100
100
SetHYHypothalamus100
100
SetLSXLateral septal complex94.31
100
SetMBMidbrain82.84
97.6
SetMYMedulla56.52
83.78
SetOLFOlfactory bulb93.99
100
SetPPons65.49
91.08
SetPALPallidum91.73
100
SetRHPRetrohippocampal region100
100
SetsAMYStriatum-like amygdalar nuclei100
100
SetSTRStriatum100
100
SetSTRdStriatum dorsal region100
95.91
SetSTRvStriatum ventral region100
100
SetTHThalamus88.46
96.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002189 29 27 55 EQQEAIEHIDEVQNEIDRLNEQASEEILK Peptide Atlas
SET_HUMAN_0 0 0 0 EFHLNESGDPSSK PRIDE
SET_HUMAN_0 0 0 0 IPNFWVTTFVNHPQVSALLGEEDEEALHYLTR PRIDE
SET_HUMAN_0 0 0 0 VEVTEFEDIK PRIDE
SET_HUMAN_122 10 122 131 VEVTEFEDIK PRIDE
SET_HUMAN_13 22 13 34 KKPRPPPALGPEETSASAGLPK PRIDE
SET_HUMAN_136 14 136 149 IDFYFDENPYFENK PRIDE
SET_HUMAN_14 21 14 34 KPRPPPALGPEETSASAGLPK PRIDE
SET_HUMAN_154 13 154 166 EFHLNESGDPSSK PRIDE
SET_HUMAN_170 10 170 179 SSQTQNKASR PRIDE
SET_HUMAN_183 10 183 192 SSQTQNKASR PRIDE
SET_HUMAN_19 26 19 44 GADETSEKEQQEAIEHIDEVQNEIDR PRIDE
SET_HUMAN_57 15 57 71 LNEQASEEILKVEQK PRIDE
SET_HUMAN_65 7 65 71 QPFFQKR PRIDE
SET_HUMAN_78 7 78 84 QPFFQKR PRIDE
SET_HUMAN_90 32 90 121 IPNFWVTTFVNHPQVSALLGEEDEEALHYLTR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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