AutismKB 2.0

Annotation Detail for MLST8


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Basic Information Top
Gene Symbol:MLST8 ( GBL,GbetaL,LST8,MGC111011,POP3,WAT1 )
Gene Full Name: MTOR associated protein, LST8 homolog (S. cerevisiae)
Band: 16p13.3
Quick LinksEntrez ID:64223; OMIM: 612190; Uniprot ID:LST8_HUMAN; ENSEMBL ID: ENSG00000167965; HGNC ID: 24825
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst7 / 62319112
fetus39 / 56401269
neonate1 / 3109732
infant3 / 23620127
juvenile10 / 55556179
adult149 / 193912176
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma2 / 8282324
colorectal tumor7 / 11424661
esophageal tumor4 / 17290231
gastrointestinal tumor6 / 11936950
germ cell tumor28 / 263845106
glioma10 / 10688393
head and neck tumor17 / 136302124
kidney tumor3 / 6895943
leukemia9 / 9584293
liver tumor0 / 963590 
lung tumor14 / 103127135
lymphoma15 / 71755209
non-neoplasia6 / 9725061
normal267 / 336030779
ovarian tumor7 / 7668291
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS41 / 125680326
prostate cancer11 / 102680107
retinoblastoma8 / 46356172
skin tumor15 / 124949120
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites5 / 40015124
bladder1 / 2975733
blood13 / 123478105
bone3 / 7165541
bone marrow1 / 4880120
brain111 / 1100989100
cervix9 / 48171186
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus4 / 20209197
eye28 / 211054132
heart6 / 8962666
intestine14 / 23447259
kidney11 / 21177751
larynx1 / 2414541
liver2 / 2077439
lung23 / 33697468
lymph6 / 44270135
lymph node2 / 9161021
mammary gland6 / 15327139
mouth1 / 6705214
muscle8 / 10771574
nerve0 / 157680 
ovary11 / 102051107
pancreas20 / 21481293
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta30 / 280825106
prostate13 / 18934568
salivary gland3 / 20155148
skin18 / 21057485
spleen8 / 53952148
stomach3 / 9661931
testis18 / 33044254
thymus11 / 81131135
thyroid11 / 47473231
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord1 / 1368073
uterus14 / 23287860
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220587_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts49.05
Adipocyte17.95
AdrenalCortex18.8
Adrenalgland15.3
Amygdala22.6
Appendix9.75
AtrioventricularNode10.8
BDCA4+_DentriticCells17.95
Bonemarrow18.15
BronchialEpithelialCells20.1
CD105+_Endothelial26.1
CD14+_Monocytes17.6
CD19+_BCells(neg._sel.)19.8
CD33+_Myeloid30.3
CD34+46.3
CD4+_Tcells19.35
CD56+_NKCells21.3
CD71+_EarlyErythroid17.05
CD8+_Tcells17.35
CardiacMyocytes17.45
Caudatenucleus16.8
Cerebellum14.75
CerebellumPeduncles26.3
CiliaryGanglion10.2
CingulateCortex18.6
Colorectaladenocarcinoma26.75
DorsalRootGanglion10.95
FetalThyroid17.75
Fetalbrain16.05
Fetalliver16.25
Fetallung12.8
GlobusPallidus11.7
Heart35.4
Hypothalamus20.2
Kidney14.75
Leukemia_chronicMyelogenousK-56221
Leukemia_promyelocytic-HL-6036.3
Leukemialymphoblastic(MOLT-4)20.35
Liver45.85
Lung32.35
Lymphnode14.95
Lymphoma_burkitts(Daudi)17.65
Lymphoma_burkitts(Raji)89.3
MedullaOblongata16.8
OccipitalLobe17.25
OlfactoryBulb11.2
Ovary12.05
Pancreas8.65
PancreaticIslet17.75
ParietalLobe19.3
Pituitary18.45
Placenta21.35
Pons15.3
PrefrontalCortex50.85
Prostate53.75
Salivarygland10.6
SkeletalMuscle12.85
Skin11.4
SmoothMuscle20.05
Spinalcord19.45
SubthalamicNucleus16
SuperiorCervicalGanglion11
TemporalLobe17.1
Testis30.3
TestisGermCell17.3
TestisIntersitial15.25
TestisLeydigCell17.9
TestisSeminiferousTubule20.65
Thalamus16.15
Thymus17.3
Thyroid41.9
Tongue15
Tonsil14.55
Trachea14.9
TrigeminalGanglion15.4
Uterus14.8
UterusCorpus12.7
WholeBlood17
Wholebrain43.45
colon16.35
pineal_day38.44
pineal_night27.4
retina27.125
small_intestine14.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6153_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.83 ± 0.63
Basal Forebrain4.1 ± 0.32
Basal Part of Pons4.77 ± 0.41
Cerebellar Cortex4.81 ± 0.54
Cerebellar Nuclei4.68 ± 0.37
Claustrum4.44 ± 0.76
Epithalamus4.36 ± 0.49
Frontal Lobe4.79 ± 0.48
Globus Pallidus4.08 ± 0.42
Hypothalamus4.09 ± 0.35
Insula4.69 ± 0.37
Limbic Lobe4.63 ± 0.57
Mesencephalon4.51 ± 0.58
Myelencephalon4.58 ± 0.57
Occipital Lobe4.31 ± 0.4
Parietal Lobe4.61 ± 0.53
Pontine Tegmentum4.44 ± 0.5
Striatum4.12 ± 0.45
Subthalamus4.65 ± 0.36
Temporal Lobe4.67 ± 0.58
Thalamus4.48 ± 0.48
White Matter4.12 ± 0.45
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00079660 18 37 54 TVQHQDSQVNALEVTPDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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