AutismKB 2.0

Annotation Detail for PDLIM2


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Basic Information Top
Gene Symbol:PDLIM2 ( FLJ34715,MYSTIQUE,SLIM )
Gene Full Name: PDZ and LIM domain 2 (mystique)
Band: 8p21.3
Quick LinksEntrez ID:64236; OMIM: 609722; Uniprot ID:PDLI2_HUMAN; ENSEMBL ID: ENSG00000120913; HGNC ID: 13992
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus15 / 56401226
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal131 / 336030738
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood7 / 12347856
bone2 / 7165527
bone marrow1 / 4880120
brain21 / 110098919
cervix3 / 4817162
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye12 / 21105456
heart1 / 8962611
intestine4 / 23447217
kidney6 / 21177728
larynx1 / 2414541
liver6 / 20774328
lung12 / 33697435
lymph0 / 442700 
lymph node8 / 9161087
mammary gland4 / 15327126
mouth1 / 6705214
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta24 / 28082585
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen10 / 53952185
stomach2 / 9661920
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219165_at
Cell line Expression level Expression bar
721_B_lymphoblasts43.45
Adipocyte136.75
AdrenalCortex13.15
Adrenalgland11.75
Amygdala14.4
Appendix11.55
AtrioventricularNode11.9
BDCA4+_DentriticCells189.55
Bonemarrow21.6
BronchialEpithelialCells52.85
CD105+_Endothelial22.55
CD14+_Monocytes271.95
CD19+_BCells(neg._sel.)226.9
CD33+_Myeloid219.75
CD34+30.35
CD4+_Tcells152
CD56+_NKCells337.95
CD71+_EarlyErythroid6.7
CD8+_Tcells164.4
CardiacMyocytes138.95
Caudatenucleus8.6
Cerebellum46.35
CerebellumPeduncles64.85
CiliaryGanglion9.65
CingulateCortex13.1
Colorectaladenocarcinoma58.35
DorsalRootGanglion18.65
FetalThyroid14.25
Fetalbrain10
Fetalliver12.1
Fetallung22.15
GlobusPallidus10.5
Heart193.2
Hypothalamus19.95
Kidney20.55
Leukemia_chronicMyelogenousK-5628.5
Leukemia_promyelocytic-HL-607.6
Leukemialymphoblastic(MOLT-4)9.3
Liver170.65
Lung592.2
Lymphnode39.3
Lymphoma_burkitts(Daudi)13.5
Lymphoma_burkitts(Raji)18.35
MedullaOblongata8.95
OccipitalLobe8.2
OlfactoryBulb101.75
Ovary12.25
Pancreas13.95
PancreaticIslet10.55
ParietalLobe9.9
Pituitary17.8
Placenta348.95
Pons9.6
PrefrontalCortex20.65
Prostate87.75
Salivarygland8.55
SkeletalMuscle17.65
Skin15.5
SmoothMuscle372.35
Spinalcord24.45
SubthalamicNucleus19.35
SuperiorCervicalGanglion15.85
TemporalLobe16.75
Testis13.5
TestisGermCell18.85
TestisIntersitial8.35
TestisLeydigCell10.3
TestisSeminiferousTubule12.6
Thalamus20.5
Thymus32.4
Thyroid28.25
Tongue77.95
Tonsil23.05
Trachea14.25
TrigeminalGanglion13.7
Uterus130.15
UterusCorpus14.65
WholeBlood245.9
Wholebrain48.2
colon22.55
pineal_day26.32
pineal_night31.26
retina96.925
small_intestine34.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P20285
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.57 ± 0.68
Basal Forebrain4.94 ± 0.4
Basal Part of Pons5.63 ± 0.7
Cerebellar Cortex5.79 ± 0.48
Cerebellar Nuclei5 ± 0.57
Claustrum4.1 ± 1.09
Epithalamus5.15 ± 0.81
Frontal Lobe5.23 ± 0.74
Globus Pallidus5.06 ± 0.58
Hypothalamus5.08 ± 0.55
Insula5.18 ± 0.61
Limbic Lobe4.63 ± 0.69
Mesencephalon5.29 ± 0.68
Myelencephalon5.12 ± 0.73
Occipital Lobe4.64 ± 0.67
Parietal Lobe4.98 ± 0.67
Pontine Tegmentum4.79 ± 0.69
Striatum4.81 ± 0.75
Subthalamus5.77 ± 0.22
Temporal Lobe5.13 ± 0.6
Thalamus5.29 ± 0.64
White Matter5.48 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pdlim2CBCerebellum19.95
15.89
Pdlim2CTXCerebral cortex5.79
3.71
Pdlim2HIPHippocampal region8.79
5.53
Pdlim2HPFHippocampal formation12.79
8.44
Pdlim2HYHypothalamus8.23
4.7
Pdlim2LSXLateral septal complex6.88
4.68
Pdlim2MBMidbrain11.14
7.82
Pdlim2MYMedulla23.49
15.87
Pdlim2OLFOlfactory bulb9.72
5.69
Pdlim2PPons26.29
18.83
Pdlim2PALPallidum5.33
3.78
Pdlim2RHPRetrohippocampal region18.95
12.01
Pdlim2sAMYStriatum-like amygdalar nuclei4.58
2.83
Pdlim2STRStriatum4.21
2.76
Pdlim2STRdStriatum dorsal region4.27
2.94
Pdlim2STRvStriatum ventral region3.19
1.73
Pdlim2THThalamus6.09
4.08
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007090 16 154 169 SFQSLACSPGLPAADR Peptide Atlas
PDLI2_HUMAN_243 11 243 253 LLQEALEAEER PRIDE
PDLI2_HUMAN_288 11 288 298 CSTSIANQAVR PRIDE
PDLI2_HUMAN_341 10 341 350 YSAPATLSSR PRIDE
PDLI2_HUMAN_341 11 341 351 YSAPATLSSRA PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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