AutismKB 2.0

Annotation Detail for SRSF3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SRSF3 ( SFRS3,SRp20 )
Gene Full Name: serine/arginine-rich splicing factor 3
Band: 6p21.31-p21.2
Quick LinksEntrez ID:6428; OMIM: 603364; Uniprot ID:SRSF3_HUMAN; ENSEMBL ID: ENSG00000112081; HGNC ID: 10785
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body27 / 70761381
blastocyst38 / 62319609
fetus122 / 564012216
neonate3 / 3109796
infant23 / 23620973
juvenile32 / 55556575
adult394 / 1939121203
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor7 / 12794547
bladder carcinoma33 / 174751888
breast (mammary gland) tumor33 / 94178350
cervical tumor15 / 34366436
chondrosarcoma27 / 82823325
colorectal tumor24 / 114246210
esophageal tumor11 / 17290636
gastrointestinal tumor34 / 119369284
germ cell tumor158 / 263845598
glioma15 / 106883140
head and neck tumor24 / 136302176
kidney tumor24 / 68959348
leukemia52 / 95842542
liver tumor41 / 96359425
lung tumor30 / 103127290
lymphoma27 / 71755376
non-neoplasia13 / 97250133
normal788 / 3360307234
ovarian tumor14 / 76682182
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS45 / 125680358
prostate cancer32 / 102680311
retinoblastoma21 / 46356453
skin tumor43 / 124949344
soft tissue/muscle tissue tumor35 / 125191279
uterine tumor23 / 90257254
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland13 / 33197391
ascites9 / 40015224
bladder42 / 297571411
blood39 / 123478315
bone21 / 71655293
bone marrow42 / 48801860
brain245 / 1100989222
cervix18 / 48171373
connective tissue25 / 149255167
ear4 / 16212246
embryonic tissue120 / 215722556
esophagus14 / 20209692
eye45 / 211054213
heart27 / 89626301
intestine54 / 234472230
kidney68 / 211777321
larynx6 / 24145248
liver66 / 207743317
lung108 / 336974320
lymph14 / 44270316
lymph node26 / 91610283
mammary gland37 / 153271241
mouth9 / 67052134
muscle28 / 107715259
nerve2 / 15768126
ovary24 / 102051235
pancreas56 / 214812260
parathyroid4 / 20539194
pharynx14 / 41328338
pituitary gland5 / 16585301
placenta53 / 280825188
prostate48 / 189345253
salivary gland9 / 20155446
skin57 / 210574270
spleen14 / 53952259
stomach26 / 96619269
testis141 / 330442426
thymus32 / 81131394
thyroid7 / 47473147
tonsil2 / 16999117
trachea15 / 52413286
umbilical cord2 / 13680146
uterus79 / 232878339
vascular23 / 51780444
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202899_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts2539.15
Adipocyte145.95
AdrenalCortex144.6
Adrenalgland113.25
Amygdala81.85
Appendix123.5
AtrioventricularNode72.55
BDCA4+_DentriticCells1223.55
Bonemarrow501.75
BronchialEpithelialCells881.35
CD105+_Endothelial1086.7
CD14+_Monocytes845.75
CD19+_BCells(neg._sel.)1012.35
CD33+_Myeloid1056.8
CD34+1405.8
CD4+_Tcells1127.75
CD56+_NKCells1104.95
CD71+_EarlyErythroid1547.05
CD8+_Tcells1179.9
CardiacMyocytes434.45
Caudatenucleus171.2
Cerebellum155.85
CerebellumPeduncles191.7
CiliaryGanglion103.15
CingulateCortex111.8
Colorectaladenocarcinoma154.9
DorsalRootGanglion81.6
FetalThyroid220.55
Fetalbrain201
Fetalliver293.3
Fetallung318
GlobusPallidus142.4
Heart58.2
Hypothalamus184.25
Kidney77.75
Leukemia_chronicMyelogenousK-562466.95
Leukemia_promyelocytic-HL-60611.8
Leukemialymphoblastic(MOLT-4)1151.8
Liver92.6
Lung96.85
Lymphnode333.15
Lymphoma_burkitts(Daudi)1383.3
Lymphoma_burkitts(Raji)104.75
MedullaOblongata169.75
OccipitalLobe219.4
OlfactoryBulb228.55
Ovary189.1
Pancreas103.85
PancreaticIslet270.15
ParietalLobe160.95
Pituitary421.7
Placenta348.35
Pons109.45
PrefrontalCortex108.9
Prostate82.6
Salivarygland174.3
SkeletalMuscle54.5
Skin72.95
SmoothMuscle616.3
Spinalcord119.9
SubthalamicNucleus171.4
SuperiorCervicalGanglion76.85
TemporalLobe117.65
Testis261.35
TestisGermCell278.25
TestisIntersitial296.85
TestisLeydigCell429.5
TestisSeminiferousTubule183.55
Thalamus179.2
Thymus832.9
Thyroid114.1
Tongue87.5
Tonsil647.3
Trachea217.25
TrigeminalGanglion74.15
Uterus99.5
UterusCorpus193.6
WholeBlood224.4
Wholebrain115.65
colon450.3
pineal_day370.76
pineal_night379.7
retina332.15
small_intestine577.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P68516
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.76 ± 0.97
Basal Forebrain2.19 ± 0.28
Basal Part of Pons2.16 ± 0.55
Cerebellar Cortex2.9 ± 0.44
Cerebellar Nuclei2.76 ± 0.82
Claustrum2.88 ± 0.72
Epithalamus3.28 ± 0.54
Frontal Lobe2.31 ± 0.73
Globus Pallidus2.81 ± 0.7
Hypothalamus2.25 ± 0.72
Insula2.04 ± 0.69
Limbic Lobe2.24 ± 0.69
Mesencephalon2.63 ± 0.75
Myelencephalon2.41 ± 0.68
Occipital Lobe2.25 ± 0.74
Parietal Lobe2.38 ± 0.8
Pontine Tegmentum2.39 ± 0.72
Striatum2.42 ± 0.76
Subthalamus2.4 ± 0.64
Temporal Lobe2.19 ± 0.68
Thalamus2.38 ± 0.64
White Matter2.72 ± 0.86
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sfrs3CBCerebellum41.23
52.22
Sfrs3CTXCerebral cortex98.15
85.79
Sfrs3HIPHippocampal region74.79
100
Sfrs3HPFHippocampal formation80.42
100
Sfrs3HYHypothalamus74.74
69.09
Sfrs3LSXLateral septal complex100
93.58
Sfrs3MBMidbrain64.71
64.92
Sfrs3MYMedulla49.02
58.32
Sfrs3OLFOlfactory bulb85.21
85.53
Sfrs3PPons49.56
56.53
Sfrs3PALPallidum66.3
67.83
Sfrs3RHPRetrohippocampal region91.51
87.48
Sfrs3sAMYStriatum-like amygdalar nuclei71.3
60.71
Sfrs3STRStriatum70.12
59.03
Sfrs3STRdStriatum dorsal region64.73
54.07
Sfrs3STRvStriatum ventral region74.74
59.58
Sfrs3THThalamus66.15
63.78
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
B2R6F3_HUMAN_12 12 12 23 VYVGNLGNNGNK PRIDE
B2R6F3_HUMAN_43 14 43 56 NPPGFAFVEFEDPR PRIDE
B2R6F3_HUMAN_43 21 43 63 NPPGFAFVEFEDPRDAADAVR PRIDE
PAp00008584 10 76 85 VRVELSNGEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved