AutismKB 2.0

Annotation Detail for FBRS


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Basic Information Top
Gene Symbol:FBRS ( FBS,FBS1,FLJ11618 )
Gene Full Name: fibrosin
Band: 16p11.2
Quick LinksEntrez ID:64319; OMIM: 608601; Uniprot ID:FBSH_HUMAN; ENSEMBL ID: ENSG00000156860; HGNC ID: 20442
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus24 / 56401242
neonate0 / 310970 
infant2 / 2362084
juvenile2 / 5555635
adult111 / 193912157
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor15 / 26384556
glioma4 / 10688337
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor3 / 9635931
lung tumor10 / 10312796
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal172 / 336030751
ovarian tumor4 / 7668252
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer10 / 10268097
retinoblastoma1 / 4635621
skin tumor10 / 12494980
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone5 / 7165569
bone marrow2 / 4880140
brain28 / 110098925
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye12 / 21105456
heart2 / 8962622
intestine11 / 23447246
kidney7 / 21177733
larynx1 / 2414541
liver3 / 20774314
lung22 / 33697465
lymph2 / 4427045
lymph node7 / 9161076
mammary gland10 / 15327165
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary6 / 10205158
pancreas20 / 21481293
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta20 / 28082571
prostate12 / 18934563
salivary gland4 / 20155198
skin13 / 21057461
spleen6 / 53952111
stomach2 / 9661920
testis37 / 330442111
thymus5 / 8113161
thyroid3 / 4747363
tonsil3 / 16999176
trachea2 / 5241338
umbilical cord0 / 136800 
uterus15 / 23287864
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218255_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts177.3
Adipocyte83.05
AdrenalCortex126.45
Adrenalgland86.7
Amygdala51.15
Appendix98.8
AtrioventricularNode91.45
BDCA4+_DentriticCells134
Bonemarrow84.45
BronchialEpithelialCells51.7
CD105+_Endothelial67.4
CD14+_Monocytes87.15
CD19+_BCells(neg._sel.)138
CD33+_Myeloid107.15
CD34+105.85
CD4+_Tcells107
CD56+_NKCells82.4
CD71+_EarlyErythroid69.9
CD8+_Tcells121.5
CardiacMyocytes95.15
Caudatenucleus91.65
Cerebellum80.95
CerebellumPeduncles109.85
CiliaryGanglion90.4
CingulateCortex92.45
Colorectaladenocarcinoma96.55
DorsalRootGanglion86.75
FetalThyroid101.1
Fetalbrain98.5
Fetalliver85.7
Fetallung53.4
GlobusPallidus97.9
Heart165.85
Hypothalamus101.6
Kidney84.9
Leukemia_chronicMyelogenousK-56295.7
Leukemia_promyelocytic-HL-60100.6
Leukemialymphoblastic(MOLT-4)88.35
Liver136.65
Lung127.45
Lymphnode93.9
Lymphoma_burkitts(Daudi)144.45
Lymphoma_burkitts(Raji)217.15
MedullaOblongata91.45
OccipitalLobe73.85
OlfactoryBulb74.85
Ovary78.75
Pancreas75.25
PancreaticIslet96.4
ParietalLobe92.9
Pituitary124.7
Placenta151
Pons160.3
PrefrontalCortex113.7
Prostate99.25
Salivarygland88.6
SkeletalMuscle171.25
Skin84.85
SmoothMuscle105.9
Spinalcord106.95
SubthalamicNucleus107.2
SuperiorCervicalGanglion128.75
TemporalLobe117.6
Testis266
TestisGermCell226.65
TestisIntersitial271.85
TestisLeydigCell234.85
TestisSeminiferousTubule185.9
Thalamus100.35
Thymus85.85
Thyroid102.9
Tongue125.7
Tonsil152.05
Trachea86.35
TrigeminalGanglion102.75
Uterus79.5
UterusCorpus61.45
WholeBlood117.35
Wholebrain55.7
colon89.7
pineal_day107.46
pineal_night106.02
retina120.425
small_intestine56.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P38015
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.4 ± 0.23
Basal Forebrain10.42 ± 0.1
Basal Part of Pons10.5 ± 0.28
Cerebellar Cortex10.74 ± 0.28
Cerebellar Nuclei10.51 ± 0.3
Claustrum10.14 ± 0.34
Epithalamus10.71 ± 0.44
Frontal Lobe10.52 ± 0.27
Globus Pallidus10.51 ± 0.19
Hypothalamus10.31 ± 0.38
Insula10.66 ± 0.2
Limbic Lobe10.54 ± 0.29
Mesencephalon10.44 ± 0.34
Myelencephalon10.59 ± 0.28
Occipital Lobe10.76 ± 0.3
Parietal Lobe10.58 ± 0.24
Pontine Tegmentum10.51 ± 0.3
Striatum10.76 ± 0.3
Subthalamus10.35 ± 0.11
Temporal Lobe10.54 ± 0.21
Thalamus10.58 ± 0.24
White Matter11.45 ± 0.03
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fbs1CBCerebellum100
100
Fbs1CTXCerebral cortex100
100
Fbs1HIPHippocampal region100
100
Fbs1HPFHippocampal formation100
100
Fbs1HYHypothalamus100
100
Fbs1LSXLateral septal complex100
100
Fbs1MBMidbrain100
100
Fbs1MYMedulla100
100
Fbs1OLFOlfactory bulb100
100
Fbs1PPons100
100
Fbs1PALPallidum100
100
Fbs1RHPRetrohippocampal region100
100
Fbs1sAMYStriatum-like amygdalar nuclei100
100
Fbs1STRStriatum100
100
Fbs1STRdStriatum dorsal region100
100
Fbs1STRvStriatum ventral region100
100
Fbs1THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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