AutismKB 2.0

Annotation Detail for RNF25


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Basic Information Top
Gene Symbol:RNF25 ( AO7,FLJ13906 )
Gene Full Name: ring finger protein 25
Band: 2q35
Quick LinksEntrez ID:64320; OMIM: NA; Uniprot ID:RNF25_HUMAN; ENSEMBL ID: ENSG00000163481; HGNC ID: 14662
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst3 / 6231948
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor12 / 94178127
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal94 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone3 / 7165541
bone marrow0 / 488010 
brain25 / 110098922
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye8 / 21105437
heart2 / 8962622
intestine5 / 23447221
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node5 / 9161054
mammary gland12 / 15327178
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta11 / 28082539
prostate2 / 18934510
salivary gland1 / 2015549
skin2 / 2105749
spleen1 / 5395218
stomach3 / 9661931
testis8 / 33044224
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218861_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.15
Adipocyte15.5
AdrenalCortex19.55
Adrenalgland13.15
Amygdala16.1
Appendix15.65
AtrioventricularNode13.75
BDCA4+_DentriticCells17.4
Bonemarrow16.25
BronchialEpithelialCells15.65
CD105+_Endothelial15.85
CD14+_Monocytes16.55
CD19+_BCells(neg._sel.)16.5
CD33+_Myeloid20.35
CD34+20.05
CD4+_Tcells16.95
CD56+_NKCells25.75
CD71+_EarlyErythroid14.3
CD8+_Tcells15.55
CardiacMyocytes20.25
Caudatenucleus14.05
Cerebellum12.95
CerebellumPeduncles17.65
CiliaryGanglion14.35
CingulateCortex15.95
Colorectaladenocarcinoma13.95
DorsalRootGanglion15.75
FetalThyroid19.9
Fetalbrain15.5
Fetalliver12.2
Fetallung11.3
GlobusPallidus14.5
Heart19.95
Hypothalamus16.65
Kidney14.65
Leukemia_chronicMyelogenousK-56214.25
Leukemia_promyelocytic-HL-6013.75
Leukemialymphoblastic(MOLT-4)12.6
Liver20.5
Lung15.3
Lymphnode13.65
Lymphoma_burkitts(Daudi)20
Lymphoma_burkitts(Raji)21.5
MedullaOblongata14.3
OccipitalLobe13.95
OlfactoryBulb12.4
Ovary10.3
Pancreas11.8
PancreaticIslet16.35
ParietalLobe19.05
Pituitary30.35
Placenta16.5
Pons15.05
PrefrontalCortex19.1
Prostate18.3
Salivarygland12.5
SkeletalMuscle21.9
Skin12
SmoothMuscle19.45
Spinalcord16.5
SubthalamicNucleus18.05
SuperiorCervicalGanglion17.6
TemporalLobe14.25
Testis13.7
TestisGermCell13.05
TestisIntersitial12.95
TestisLeydigCell15.5
TestisSeminiferousTubule13.55
Thalamus15.9
Thymus12.6
Thyroid16.5
Tongue15.3
Tonsil15.35
Trachea13.15
TrigeminalGanglion15.45
Uterus12.75
UterusCorpus13.8
WholeBlood16.6
Wholebrain13.3
colon12.5
pineal_day21.14
pineal_night18.82
retina18.675
small_intestine11.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1858_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.79 ± 0.44
Basal Forebrain6.54 ± 0.27
Basal Part of Pons6.15 ± 0.38
Cerebellar Cortex6.22 ± 0.35
Cerebellar Nuclei6.33 ± 0.41
Claustrum6.85 ± 0.59
Epithalamus5.95 ± 0.51
Frontal Lobe6.33 ± 0.37
Globus Pallidus6.65 ± 0.25
Hypothalamus6.49 ± 0.39
Insula6.23 ± 0.37
Limbic Lobe6.75 ± 0.46
Mesencephalon6.6 ± 0.4
Myelencephalon6.52 ± 0.39
Occipital Lobe6.8 ± 0.48
Parietal Lobe6.5 ± 0.43
Pontine Tegmentum6.44 ± 0.44
Striatum6.59 ± 0.42
Subthalamus6.13 ± 0.12
Temporal Lobe6.42 ± 0.37
Thalamus6.45 ± 0.3
White Matter6.93 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rnf25CBCerebellum100
100
Rnf25CTXCerebral cortex100
100
Rnf25HIPHippocampal region100
100
Rnf25HPFHippocampal formation100
100
Rnf25HYHypothalamus100
100
Rnf25LSXLateral septal complex100
100
Rnf25MBMidbrain100
100
Rnf25MYMedulla90.12
100
Rnf25OLFOlfactory bulb100
100
Rnf25PPons87.38
100
Rnf25PALPallidum100
100
Rnf25RHPRetrohippocampal region100
100
Rnf25sAMYStriatum-like amygdalar nuclei100
100
Rnf25STRStriatum100
100
Rnf25STRdStriatum dorsal region100
100
Rnf25STRvStriatum ventral region100
100
Rnf25THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
RNF25_HUMAN_78 10 78 87 VPQISIRNPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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