AutismKB 2.0

Annotation Detail for NFKBIZ


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Basic Information Top
Gene Symbol:NFKBIZ ( FLJ30225,FLJ34463,IKBZ,INAP,MAIL )
Gene Full Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Band: 3q12.3
Quick LinksEntrez ID:64332; OMIM: 608004; Uniprot ID:IKBZ_HUMAN; ENSEMBL ID: ENSG00000144802; HGNC ID: 29805
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus20 / 56401235
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult96 / 193912149
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor10 / 11936983
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma2 / 7175527
non-neoplasia8 / 9725082
normal121 / 336030736
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood7 / 12347856
bone2 / 7165527
bone marrow3 / 4880161
brain6 / 11009895
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye11 / 21105452
heart3 / 8962633
intestine9 / 23447238
kidney3 / 21177714
larynx1 / 2414541
liver6 / 20774328
lung33 / 33697497
lymph0 / 442700 
lymph node5 / 9161054
mammary gland9 / 15327158
mouth1 / 6705214
muscle4 / 10771537
nerve0 / 157680 
ovary3 / 10205129
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta6 / 28082521
prostate0 / 1893450 
salivary gland1 / 2015549
skin10 / 21057447
spleen2 / 5395237
stomach11 / 96619113
testis1 / 3304423
thymus4 / 8113149
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15937_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.58 ± 0.48
Basal Forebrain4.44 ± 0.41
Basal Part of Pons5.2 ± 0.31
Cerebellar Cortex4.63 ± 0.44
Cerebellar Nuclei4.91 ± 0.44
Claustrum4.54 ± 0.68
Epithalamus4.29 ± 0.45
Frontal Lobe4.55 ± 0.51
Globus Pallidus5.25 ± 0.49
Hypothalamus4.22 ± 0.71
Insula4.34 ± 0.54
Limbic Lobe4.57 ± 0.65
Mesencephalon4.36 ± 0.55
Myelencephalon4.61 ± 0.59
Occipital Lobe4.85 ± 0.51
Parietal Lobe4.58 ± 0.52
Pontine Tegmentum4.34 ± 0.47
Striatum4.72 ± 0.58
Subthalamus4.64 ± 0.11
Temporal Lobe4.4 ± 0.55
Thalamus4.65 ± 0.48
White Matter5.08 ± 0.07
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NfkbizCBCerebellum1.77
1.64
NfkbizCTXCerebral cortex3.5
2.36
NfkbizHIPHippocampal region9.1
9.71
NfkbizHPFHippocampal formation7.51
7.33
NfkbizHYHypothalamus1.43
1.11
NfkbizLSXLateral septal complex0.81
0.93
NfkbizMBMidbrain1.12
1.2
NfkbizMYMedulla1.75
2.04
NfkbizOLFOlfactory bulb5.58
4.18
NfkbizPPons3.35
4.45
NfkbizPALPallidum2.1
1.64
NfkbizRHPRetrohippocampal region4.35
3.47
NfkbizsAMYStriatum-like amygdalar nuclei0.52
0.4
NfkbizSTRStriatum1.56
1.19
NfkbizSTRdStriatum dorsal region0.86
0.75
NfkbizSTRvStriatum ventral region5.49
3.23
NfkbizTHThalamus4.47
3.82
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018