AutismKB 2.0

Annotation Detail for TRA2B


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Basic Information Top
Gene Symbol:TRA2B ( DKFZp686F18120,Htra2-beta,SFRS10,SRFS10,TRA2-BETA,TRAN2B )
Gene Full Name: transformer 2 beta homolog (Drosophila)
Band: 3q27.2
Quick LinksEntrez ID:6434; OMIM: 602719; Uniprot ID:TRA2B_HUMAN; ENSEMBL ID: ENSG00000136527; HGNC ID: 10781
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst17 / 62319272
fetus87 / 564012154
neonate6 / 31097192
infant19 / 23620804
juvenile29 / 55556521
adult340 / 1939121175
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor28 / 94178297
cervical tumor8 / 34366232
chondrosarcoma7 / 8282384
colorectal tumor12 / 114246105
esophageal tumor5 / 17290289
gastrointestinal tumor19 / 119369159
germ cell tumor72 / 263845272
glioma14 / 106883130
head and neck tumor28 / 136302205
kidney tumor11 / 68959159
leukemia16 / 95842166
liver tumor15 / 96359155
lung tumor17 / 103127164
lymphoma14 / 71755195
non-neoplasia20 / 97250205
normal590 / 3360307175
ovarian tumor15 / 76682195
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS61 / 125680485
prostate cancer29 / 102680282
retinoblastoma10 / 46356215
skin tumor32 / 124949256
soft tissue/muscle tissue tumor19 / 125191151
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland10 / 33197301
ascites5 / 40015124
bladder9 / 29757302
blood21 / 123478170
bone14 / 71655195
bone marrow11 / 48801225
brain190 / 1100989172
cervix11 / 48171228
connective tissue24 / 149255160
ear8 / 16212493
embryonic tissue52 / 215722241
esophagus5 / 20209247
eye33 / 211054156
heart17 / 89626189
intestine54 / 234472230
kidney38 / 211777179
larynx5 / 24145207
liver29 / 207743139
lung55 / 336974163
lymph4 / 4427090
lymph node15 / 91610163
mammary gland35 / 153271228
mouth4 / 6705259
muscle12 / 107715111
nerve2 / 15768126
ovary17 / 102051166
pancreas19 / 21481288
parathyroid3 / 20539146
pharynx10 / 41328241
pituitary gland1 / 1658560
placenta67 / 280825238
prostate42 / 189345221
salivary gland2 / 2015599
skin42 / 210574199
spleen14 / 53952259
stomach23 / 96619238
testis80 / 330442242
thymus36 / 81131443
thyroid9 / 47473189
tonsil0 / 169990 
trachea15 / 52413286
umbilical cord0 / 136800 
uterus47 / 232878201
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210180_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts34.5
Adipocyte5.35
AdrenalCortex6.2
Adrenalgland4.7
Amygdala5.6
Appendix5.9
AtrioventricularNode4.45
BDCA4+_DentriticCells74.15
Bonemarrow5.6
BronchialEpithelialCells5.4
CD105+_Endothelial30.15
CD14+_Monocytes21.45
CD19+_BCells(neg._sel.)87.5
CD33+_Myeloid81.8
CD34+23.65
CD4+_Tcells41.05
CD56+_NKCells68.05
CD71+_EarlyErythroid28.1
CD8+_Tcells36.35
CardiacMyocytes7.85
Caudatenucleus4.85
Cerebellum4.4
CerebellumPeduncles6.3
CiliaryGanglion4.05
CingulateCortex5.6
Colorectaladenocarcinoma5.55
DorsalRootGanglion4.4
FetalThyroid5.5
Fetalbrain5.35
Fetalliver4.75
Fetallung4.35
GlobusPallidus4.15
Heart7.65
Hypothalamus5.8
Kidney4.6
Leukemia_chronicMyelogenousK-5624.95
Leukemia_promyelocytic-HL-604.9
Leukemialymphoblastic(MOLT-4)5.7
Liver7.45
Lung7.65
Lymphnode4.65
Lymphoma_burkitts(Daudi)7.1
Lymphoma_burkitts(Raji)8.1
MedullaOblongata4.9
OccipitalLobe4.9
OlfactoryBulb4.35
Ovary3.75
Pancreas4.4
PancreaticIslet5.9
ParietalLobe5.9
Pituitary6.25
Placenta5.6
Pons5.25
PrefrontalCortex6.65
Prostate9.15
Salivarygland4.45
SkeletalMuscle6.95
Skin4.5
SmoothMuscle6.2
Spinalcord5.75
SubthalamicNucleus5.05
SuperiorCervicalGanglion7.15
TemporalLobe5.05
Testis4.7
TestisGermCell4.5
TestisIntersitial4.65
TestisLeydigCell5.7
TestisSeminiferousTubule4.65
Thalamus5.55
Thymus4.4
Thyroid6.8
Tongue5.55
Tonsil5.4
Trachea4.6
TrigeminalGanglion5.9
Uterus4.7
UterusCorpus5.45
WholeBlood5.85
Wholebrain4.35
colon5.55
pineal_day6.76
pineal_night6.62
retina6.625
small_intestine5.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11806_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.58 ± 0.56
Basal Forebrain6.91 ± 0.2
Basal Part of Pons7.03 ± 0.34
Cerebellar Cortex7.17 ± 0.25
Cerebellar Nuclei6.81 ± 0.37
Claustrum6.29 ± 0.6
Epithalamus7.12 ± 0.33
Frontal Lobe6.9 ± 0.35
Globus Pallidus6.69 ± 0.2
Hypothalamus6.93 ± 0.31
Insula6.94 ± 0.27
Limbic Lobe6.68 ± 0.42
Mesencephalon6.77 ± 0.39
Myelencephalon6.81 ± 0.4
Occipital Lobe6.69 ± 0.43
Parietal Lobe6.79 ± 0.35
Pontine Tegmentum6.8 ± 0.33
Striatum6.53 ± 0.32
Subthalamus7.07 ± 0.23
Temporal Lobe6.98 ± 0.32
Thalamus6.9 ± 0.3
White Matter7.23 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sfrs10CBCerebellum2.08
2.55
Sfrs10CTXCerebral cortex4.8
3.67
Sfrs10HIPHippocampal region7.7
8.96
Sfrs10HPFHippocampal formation6.27
7.01
Sfrs10HYHypothalamus2.05
1.43
Sfrs10LSXLateral septal complex0.84
0.64
Sfrs10MBMidbrain1.62
2.08
Sfrs10MYMedulla1.5
1.98
Sfrs10OLFOlfactory bulb4.52
4.15
Sfrs10PPons2.03
2.65
Sfrs10PALPallidum0.86
0.66
Sfrs10RHPRetrohippocampal region3.58
4.18
Sfrs10sAMYStriatum-like amygdalar nuclei0.38
0.29
Sfrs10STRStriatum0.86
0.76
Sfrs10STRdStriatum dorsal region0.68
0.71
Sfrs10STRvStriatum ventral region1.78
1.3
Sfrs10THThalamus2.44
2.32
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00081600 16 141 156 YGPIADVSIVYDQQSR Peptide Atlas
TRA2B_HUMAN_179 9 179 187 ANGMELDGR PRIDE
TRA2B_HUMAN_199 12 199 210 PHTPTPGIYMGR PRIDE
TRA2B_HUMAN_2 11 2 12 SDSGEQNYGER PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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