AutismKB 2.0

Annotation Detail for MMP25


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MMP25 ( MMP-25,MMP20,MMP20A,MMPL1,MT-MMP 6,MT-MMP6,MT6-MMP,MT6MMP,MTMMP6 )
Gene Full Name: matrix metallopeptidase 25
Band: 16p13.3
Quick LinksEntrez ID:64386; OMIM: 608482; Uniprot ID:MMP25_HUMAN; ENSEMBL ID: ENSG00000008516; HGNC ID: 14246
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal35 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood10 / 12347880
bone0 / 716550 
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye1 / 2110544
heart2 / 8962622
intestine3 / 23447212
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen5 / 5395292
stomach0 / 966190 
testis2 / 3304426
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207890_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts19.85
Adipocyte27.05
AdrenalCortex36.15
Adrenalgland46.8
Amygdala28.1
Appendix40.3
AtrioventricularNode28.7
BDCA4+_DentriticCells13.8
Bonemarrow67.95
BronchialEpithelialCells26.1
CD105+_Endothelial15.2
CD14+_Monocytes34.5
CD19+_BCells(neg._sel.)23.95
CD33+_Myeloid28.5
CD34+33.2
CD4+_Tcells20.6
CD56+_NKCells17.7
CD71+_EarlyErythroid26.55
CD8+_Tcells17.9
CardiacMyocytes35.55
Caudatenucleus28.15
Cerebellum25
CerebellumPeduncles63.65
CiliaryGanglion22.4
CingulateCortex38.6
Colorectaladenocarcinoma27.55
DorsalRootGanglion23.25
FetalThyroid34.95
Fetalbrain28.55
Fetalliver23.9
Fetallung16.9
GlobusPallidus29.9
Heart45.25
Hypothalamus29.15
Kidney28.1
Leukemia_chronicMyelogenousK-56231.1
Leukemia_promyelocytic-HL-6027.05
Leukemialymphoblastic(MOLT-4)30.3
Liver42.15
Lung30.5
Lymphnode33.35
Lymphoma_burkitts(Daudi)43.15
Lymphoma_burkitts(Raji)31.5
MedullaOblongata26.35
OccipitalLobe25.55
OlfactoryBulb23.45
Ovary23.3
Pancreas23.7
PancreaticIslet30.2
ParietalLobe38.75
Pituitary58.6
Placenta22.2
Pons39
PrefrontalCortex26.55
Prostate24.5
Salivarygland30.9
SkeletalMuscle46.95
Skin24.9
SmoothMuscle32.3
Spinalcord40.25
SubthalamicNucleus28.25
SuperiorCervicalGanglion39.5
TemporalLobe26.1
Testis24.35
TestisGermCell22.4
TestisIntersitial24.15
TestisLeydigCell29.85
TestisSeminiferousTubule30.4
Thalamus53.2
Thymus22.9
Thyroid18.6
Tongue37.65
Tonsil35.8
Trachea31.8
TrigeminalGanglion34.4
Uterus18.5
UterusCorpus20.75
WholeBlood143.85
Wholebrain18.9
colon21.75
pineal_day22.56
pineal_night19.02
retina29.125
small_intestine16.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11519_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.7 ± 1.19
Basal Forebrain2.39 ± 0.45
Basal Part of Pons2.27 ± 0.75
Cerebellar Cortex2.54 ± 0.99
Cerebellar Nuclei3.09 ± 0.85
Claustrum3.1 ± 0.88
Epithalamus2.36 ± 1.14
Frontal Lobe2.36 ± 1.06
Globus Pallidus2.73 ± 0.66
Hypothalamus2.61 ± 1.04
Insula2.03 ± 0.63
Limbic Lobe2.47 ± 0.9
Mesencephalon2.59 ± 0.88
Myelencephalon2.51 ± 1.02
Occipital Lobe2.61 ± 1.11
Parietal Lobe2.46 ± 1.15
Pontine Tegmentum2.45 ± 0.87
Striatum2.41 ± 0.97
Subthalamus2.18 ± 0.74
Temporal Lobe2.36 ± 1.04
Thalamus2.32 ± 0.94
White Matter2.47 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mmp25CBCerebellum83.67
100
Mmp25CTXCerebral cortex15.98
12.57
Mmp25HIPHippocampal region4.41
4.95
Mmp25HPFHippocampal formation3.83
4.24
Mmp25HYHypothalamus0.86
0.98
Mmp25LSXLateral septal complex0.64
0.59
Mmp25MBMidbrain2.1
2.47
Mmp25MYMedulla6.42
6.87
Mmp25OLFOlfactory bulb25.66
31.46
Mmp25PPons0.71
0.84
Mmp25PALPallidum1.28
1.23
Mmp25RHPRetrohippocampal region2.74
3.04
Mmp25sAMYStriatum-like amygdalar nuclei1.42
2.05
Mmp25STRStriatum3.62
3.23
Mmp25STRdStriatum dorsal region2.93
2.49
Mmp25STRvStriatum ventral region8.21
6.85
Mmp25THThalamus0.94
1.08
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved