AutismKB 2.0

Annotation Detail for SFTPB


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Basic Information Top
Gene Symbol:SFTPB ( PSP-B,SFTB3,SFTP3,SMDP1,SP-B )
Gene Full Name: surfactant protein B
Band: 2p11.2
Quick LinksEntrez ID:6439; OMIM: 178640; Uniprot ID:PSPB_HUMAN; ENSEMBL ID: ENSG00000168878; HGNC ID: 10801
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult191 / 193912198
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma28 / 82823338
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor47 / 103127455
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal161 / 336030747
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain1 / 11009890 
cervix0 / 481710 
connective tissue28 / 149255187
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine5 / 23447221
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung214 / 336974635
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid9 / 47473189
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213936_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.4
Adipocyte5.2
AdrenalCortex5.8
Adrenalgland4.45
Amygdala5.35
Appendix6
AtrioventricularNode5.6
BDCA4+_DentriticCells5.7
Bonemarrow5.2
BronchialEpithelialCells5
CD105+_Endothelial5.65
CD14+_Monocytes5.6
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid6.7
CD34+6.55
CD4+_Tcells5.8
CD56+_NKCells6.25
CD71+_EarlyErythroid4.8
CD8+_Tcells5.1
CardiacMyocytes6.45
Caudatenucleus4.6
Cerebellum4.3
CerebellumPeduncles6.1
CiliaryGanglion3.9
CingulateCortex5.5
Colorectaladenocarcinoma5.35
DorsalRootGanglion4.3
FetalThyroid5.05
Fetalbrain5.2
Fetalliver4.55
Fetallung1232.7
GlobusPallidus3.9
Heart6.7
Hypothalamus5.6
Kidney4.2
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.7
Leukemialymphoblastic(MOLT-4)4.2
Liver6.85
Lung5440.6
Lymphnode4.55
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)7.45
MedullaOblongata4.8
OccipitalLobe4.75
OlfactoryBulb4.15
Ovary3.55
Pancreas4.35
PancreaticIslet5.7
ParietalLobe5.7
Pituitary6.15
Placenta5.3
Pons5.05
PrefrontalCortex6.6
Prostate6.25
Salivarygland4.15
SkeletalMuscle5.9
Skin4.35
SmoothMuscle5.85
Spinalcord5.5
SubthalamicNucleus4.85
SuperiorCervicalGanglion7.05
TemporalLobe4.75
Testis4.5
TestisGermCell4.35
TestisIntersitial4.5
TestisLeydigCell5.25
TestisSeminiferousTubule4.5
Thalamus5.25
Thymus4.2
Thyroid6.55
Tongue5.9
Tonsil5.5
Trachea4.45
TrigeminalGanglion5.85
Uterus4.4
UterusCorpus4.65
WholeBlood5.6
Wholebrain4.25
colon5.5
pineal_day7.58
pineal_night7.4
retina6.45
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P188065
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.76 ± 1
Basal Forebrain2 ± 0.22
Basal Part of Pons1.78 ± 0.59
Cerebellar Cortex1.95 ± 0.76
Cerebellar Nuclei2.44 ± 0.71
Claustrum3.06 ± 0.95
Epithalamus2.04 ± 1.1
Frontal Lobe2.06 ± 0.9
Globus Pallidus2.86 ± 0.67
Hypothalamus2.12 ± 0.7
Insula1.89 ± 0.69
Limbic Lobe2.17 ± 0.76
Mesencephalon2.29 ± 0.73
Myelencephalon2.17 ± 0.83
Occipital Lobe2.34 ± 0.88
Parietal Lobe2.07 ± 0.73
Pontine Tegmentum2.25 ± 0.74
Striatum2.26 ± 0.61
Subthalamus2.22 ± 0.71
Temporal Lobe1.96 ± 0.63
Thalamus2.04 ± 0.64
White Matter2.26 ± 0.15
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00037866 19 145 163 SRQPEPEQEPGMSDPLPKP Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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