AutismKB 2.0

Annotation Detail for ZFP106


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Basic Information Top
Gene Symbol:ZFP106 ( DKFZp451A239,FLJ34610,FLJ45841,SH3BP3,ZNF474 )
Gene Full Name: zinc finger protein 106 homolog (mouse)
Band: 15q15.1
Quick LinksEntrez ID:64397; OMIM: NA; Uniprot ID:ZF106_HUMAN; ENSEMBL ID: ENSG00000103994; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst7 / 62319112
fetus67 / 564012118
neonate3 / 3109796
infant1 / 2362042
juvenile7 / 55556125
adult216 / 1939121111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor20 / 94178212
cervical tumor5 / 34366145
chondrosarcoma8 / 8282396
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor25 / 26384594
glioma1 / 1068839
head and neck tumor10 / 13630273
kidney tumor3 / 6895943
leukemia11 / 95842114
liver tumor8 / 9635983
lung tumor2 / 10312719
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal447 / 3360307133
ovarian tumor5 / 7668265
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor34 / 124949272
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland3 / 3319790
ascites1 / 4001524
bladder0 / 297570 
blood16 / 123478129
bone3 / 7165541
bone marrow3 / 4880161
brain81 / 110098973
cervix5 / 48171103
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue27 / 215722125
esophagus1 / 2020949
eye14 / 21105466
heart41 / 89626457
intestine8 / 23447234
kidney22 / 211777103
larynx3 / 24145124
liver19 / 20774391
lung16 / 33697447
lymph3 / 4427067
lymph node34 / 91610371
mammary gland30 / 153271195
mouth15 / 67052223
muscle59 / 107715547
nerve2 / 15768126
ovary6 / 10205158
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta14 / 28082549
prostate17 / 18934589
salivary gland1 / 2015549
skin57 / 210574270
spleen3 / 5395255
stomach5 / 9661951
testis41 / 330442124
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord1 / 1368073
uterus28 / 232878120
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217781_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts91.2
Adipocyte586.15
AdrenalCortex47.45
Adrenalgland65.35
Amygdala218.6
Appendix29.8
AtrioventricularNode25.5
BDCA4+_DentriticCells121.05
Bonemarrow35.8
BronchialEpithelialCells65.05
CD105+_Endothelial78.5
CD14+_Monocytes309.3
CD19+_BCells(neg._sel.)81.3
CD33+_Myeloid456.6
CD34+158.55
CD4+_Tcells43.45
CD56+_NKCells157.6
CD71+_EarlyErythroid27.3
CD8+_Tcells46.15
CardiacMyocytes24.6
Caudatenucleus230.6
Cerebellum52.55
CerebellumPeduncles65.3
CiliaryGanglion22.45
CingulateCortex149.55
Colorectaladenocarcinoma64.1
DorsalRootGanglion40.1
FetalThyroid65.1
Fetalbrain59.05
Fetalliver17.9
Fetallung70.5
GlobusPallidus158.75
Heart58.65
Hypothalamus230.25
Kidney30.75
Leukemia_chronicMyelogenousK-56250.35
Leukemia_promyelocytic-HL-60151.7
Leukemialymphoblastic(MOLT-4)49.2
Liver25.35
Lung21.95
Lymphnode51.7
Lymphoma_burkitts(Daudi)27.75
Lymphoma_burkitts(Raji)109.65
MedullaOblongata198.5
OccipitalLobe151.5
OlfactoryBulb216.05
Ovary36.5
Pancreas26.4
PancreaticIslet45.1
ParietalLobe156.25
Pituitary188.25
Placenta66.7
Pons208.45
PrefrontalCortex409.6
Prostate46.4
Salivarygland92.5
SkeletalMuscle856.3
Skin16.65
SmoothMuscle82.55
Spinalcord146.45
SubthalamicNucleus120.65
SuperiorCervicalGanglion26.45
TemporalLobe123.4
Testis32
TestisGermCell87.95
TestisIntersitial39.15
TestisLeydigCell57.05
TestisSeminiferousTubule77
Thalamus190.45
Thymus30.15
Thyroid166.1
Tongue442.6
Tonsil88.7
Trachea39.75
TrigeminalGanglion24.1
Uterus109.3
UterusCorpus19.85
WholeBlood302.6
Wholebrain62.25
colon38.15
pineal_day421.46
pineal_night405.96
retina245.225
small_intestine46.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1837_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.09 ± 0.36
Basal Forebrain6.87 ± 0.27
Basal Part of Pons6.55 ± 0.25
Cerebellar Cortex6.36 ± 0.27
Cerebellar Nuclei6.83 ± 0.24
Claustrum7.25 ± 0.48
Epithalamus7.03 ± 0.13
Frontal Lobe6.66 ± 0.39
Globus Pallidus6.98 ± 0.19
Hypothalamus6.48 ± 0.48
Insula6.73 ± 0.31
Limbic Lobe6.77 ± 0.36
Mesencephalon6.9 ± 0.33
Myelencephalon6.73 ± 0.41
Occipital Lobe6.9 ± 0.25
Parietal Lobe6.85 ± 0.43
Pontine Tegmentum6.8 ± 0.5
Striatum7.16 ± 0.41
Subthalamus6.77 ± 0.32
Temporal Lobe6.69 ± 0.36
Thalamus6.64 ± 0.3
White Matter6.56 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp106CBCerebellum12.55
12.79
Zfp106CTXCerebral cortex75.1
48.14
Zfp106HIPHippocampal region50.17
74.8
Zfp106HPFHippocampal formation55.47
62.21
Zfp106HYHypothalamus47.29
28.54
Zfp106LSXLateral septal complex7.02
4.16
Zfp106MBMidbrain49.37
33.69
Zfp106MYMedulla55.7
46.08
Zfp106OLFOlfactory bulb51.66
33.6
Zfp106PPons57.55
44.5
Zfp106PALPallidum49.99
33.06
Zfp106RHPRetrohippocampal region68.97
44.83
Zfp106sAMYStriatum-like amygdalar nuclei41.82
22.87
Zfp106STRStriatum41.33
23.4
Zfp106STRdStriatum dorsal region45.27
25.92
Zfp106STRvStriatum ventral region46.6
25.32
Zfp106THThalamus58.55
42.21
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00077359 15 1470 1484 SGCDEVSSTSEIGTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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