AutismKB 2.0

Annotation Detail for HHIP


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Basic Information Top
Gene Symbol:HHIP ( FLJ20992,FLJ90230,HIP )
Gene Full Name: hedgehog interacting protein
Band: 4q31.21
Quick LinksEntrez ID:64399; OMIM: 606178; Uniprot ID:HHIP_HUMAN; ENSEMBL ID: ENSG00000164161; HGNC ID: 14866
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate5 / 31097160
infant1 / 2362042
juvenile1 / 5555617
adult60 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal126 / 336030737
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor49 / 125191391
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain34 / 110098930
cervix0 / 481710 
connective tissue45 / 149255301
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine1 / 2344724
kidney26 / 211777122
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph1 / 4427022
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle10 / 10771592
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord5 / 13680365
uterus2 / 2328788
vascular64 / 517801235
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14024_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.14 ± 1.35
Basal Forebrain4.99 ± 0.8
Basal Part of Pons4.94 ± 0.95
Cerebellar Cortex4.6 ± 0.6
Cerebellar Nuclei5.83 ± 0.52
Claustrum4.28 ± 0.8
Epithalamus4.48 ± 1.21
Frontal Lobe5.12 ± 1.2
Globus Pallidus7.19 ± 0.44
Hypothalamus4.69 ± 0.56
Insula4.42 ± 1.01
Limbic Lobe4.99 ± 1.25
Mesencephalon5.21 ± 0.84
Myelencephalon5.3 ± 0.99
Occipital Lobe5.13 ± 1.06
Parietal Lobe5.03 ± 1.15
Pontine Tegmentum5.36 ± 0.9
Striatum6.2 ± 0.91
Subthalamus5.75 ± 0.51
Temporal Lobe4.94 ± 1
Thalamus5.91 ± 0.7
White Matter8.69 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
HhipCBCerebellum6.58
7.72
HhipCTXCerebral cortex3.25
2.74
HhipHIPHippocampal region3.31
4.26
HhipHPFHippocampal formation4.07
4.2
HhipHYHypothalamus1
0.86
HhipLSXLateral septal complex5.15
4.37
HhipMBMidbrain3.27
3.27
HhipMYMedulla6.06
7.56
HhipOLFOlfactory bulb5.51
4.83
HhipPPons5.1
6.28
HhipPALPallidum5.4
5.11
HhipRHPRetrohippocampal region5.39
4.21
HhipsAMYStriatum-like amygdalar nuclei2.29
2.09
HhipSTRStriatum6.83
7.85
HhipSTRdStriatum dorsal region7.34
9.2
HhipSTRvStriatum ventral region8.5
8.45
HhipTHThalamus2.24
3.52
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018